SCHEMBL3083049

SCHEMBL3083049

O=C(O)c1occc1[N+](=O)[O-]

nearest known ligand 0.46

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CASP6 P55212 1/20 0.44
TSHR P16473 3/20 0.41
TDP1 Q9NUW8 2/20 0.41
LMNA P02545 2/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
DTYMK P23919 1/20 0.40
HCAR3 P49019 2/20 0.38
GPR35 Q9HC97 1/20 0.38
KMT2A Q03164 1/20 0.38
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL6429065 0.98 CASP6 (0.43) CASP6TSHRTDP1LMNAL3MBTL1
Ammonia Solution, Strong SCHEMBL30580416 0.98 CASP6 (0.43) CASP6TSHRTDP1LMNAL3MBTL1
SCHEMBL6429062 0.84 ALDH1A1 (0.42) CASP6TSHRTDP1LMNAGPR35
SCHEMBL30580417 0.82 CA1 (0.38) CASP6TDP1GPR35KMT2ACA1
SCHEMBL3264461 0.82 PARP1 (0.42) TSHRLMNAL3MBTL1GPR35KMT2A
SCHEMBL30580418 0.82 CA1 (0.38) CASP6TDP1L3MBTL1GPR35KMT2A
SCHEMBL12559304 0.82 MAPK1 (0.41) TSHRTDP1LMNAL3MBTL1GPR35
Potassium Ion SCHEMBL30721056 0.82 CA1 (0.38) CASP6TDP1GPR35KMT2ACA1
SCHEMBL11017953 0.82 CASP6 (0.36) CASP6TSHRTDP1LMNAL3MBTL1
SCHEMBL2039324 0.78 VCAM1 (0.43) TSHRTDP1LMNAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005007625-A2 HETEROCYCLIC AMIDES WITH ANTI-TUBERCULOSIS ACTIVITY THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) 2005-01-27 WO claimed
US-20250386828-A1 PLANT GROWTH PROMOTER NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2025-12-25 US disclosed
WO-2024024851-A1 AGENT FOR SUPPRESSING DECREASE IN YIELD AMOUNT デンカ株式会社 2024-02-01 WO disclosed
WO-2023176347-A1 METHOD FOR CULTIVATING CITRUS PLANT, AND LIQUID COMPOSITION デンカ株式会社 2023-09-21 WO disclosed
US-20110144321-A1 SYNTHETIC INTERMEDIATES AND PROCESSES BIOCRYST PHARMACEUTICALS, INC. (US) 2011-06-16 US disclosed
US-20110144321-A1 SYNTHETIC INTERMEDIATES AND PROCESSES BIOCRYST PHARMACEUTICALS, INC. (US) 2011-06-16 US disclosed
US-7833331-B2 Non-toxic corrosion-protection pigments based on cobalt UNIVERSITY OF DAYTON (US) 2010-11-16 US disclosed
US-7789958-B2 Non-toxic corrosion-protection pigments based on manganese UNIVERSITY OF DAYTON (US) 2010-09-07 US disclosed
WO-2010011748-A2 SYNTHETIC INTERMEDIATES AND PROCESSES BIOCRYST PHARMACEUTICALS, INC. (US) 2010-01-28 WO disclosed
US-20090163628-A1 NON-TOXIC CORROSION-PROTECTION PIGMENTS BASED ON COBALT STURGILL JEFFREY ALLEN 2009-06-25 US disclosed
WO-2003060192-A1 NON-TOXIC CORROSION-PROTECTION RINSES AND SEALS BASED ON COBALT UNIVERSITY OF DAYTON (US) 2003-07-24 WO disclosed
WO-2003060191-A2 NON-TOXIC CORROSION-PROTECTION CONVERSION COATINGES ABSED ON COBALT UNIVERSITY OF DAYTON (US) 2003-07-24 WO disclosed
WO-2003060019-A1 NON-TOXIC CORROSION PROTECTION PIGMENTS BASED ON COBALT UNIVERSITY OF DAYTON (US) 2003-07-24 WO disclosed
US-6448443-B1 GENERATED FROM DIVERSIFIABLE SCAFFOLDS SYNTHESIZED FROM THE PYRIDINE-BASED TEMPLATE ISONICOTINAMIDE; ALSO PROVIDES A NOVEL ORTHO-NITROBENZYL PHOTOLINKER; SYNTHESIZED FROM A SHIKIMIC ACID BASED EPOXYOL TEMPLATE PRESIDENT AND FELLOWS OF HARVARD COLLEGE 2002-09-10 US disclosed
US-6201013-B1 INOSINE MONOPHOSPHATE DEHYDROGENASE (IMPDH) INHIBITOR; SIDE EFFECT REDUCTION, NON-DRUG RESISTANT AMERICAN HOME PRODUCTS CORPORATION 2001-03-13 US disclosed
EP-0595995-A4 ARYLAMIDOALKYL-N-HYDROXYUREA COMPOUNDS HAVING LIPOXYGENASE INHIBITORY ACTIVITY ABBOTT LAB (US) 1994-08-24 EP disclosed
EP-0595995-A1 ARYLAMIDOALKYL-N-HYDROXYUREA COMPOUNDS HAVING LIPOXYGENASE INHIBITORY ACTIVITY. ABBOTT LAB (US) 1994-05-11 EP disclosed
WO-1993002037-A1 ARYLAMIDOALKYL-N-HYDROXYUREA COMPOUNDS HAVING LIPOXYGENASE INHIBITORY ACTIVITY ABBOTT LABORATORIES (US) 1993-02-04 WO disclosed
US-5153210-A Hypoglycemic agent, animal growth regulator; veterinary medicine BEECHAM GROUP P.L.C. (GB) 1992-10-06 US disclosed
EP-0236624-A2 Substituted phenyl ethanol amines, processes for their preparation and pharmaceutical compositions containing them BEECHAM GROUP PLC (GB) 1987-09-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110144321-A1 SYNTHETIC INTERMEDIATES AND PROCESSES G6PD, GALE, UGGT1 CASP6 2912/4885TSHR 1519/4885TDP1 1487/4885
US-20250386828-A1 PLANT GROWTH PROMOTER MYB, GHITM, PGLS CASP6 2133/4885TSHR 2129/4885TDP1 3007/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.