SCHEMBL30866535

SCHEMBL30866535

Cc1cncc([C@H]2CCCN2C)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRNB4 P30926 6/20 0.64
CHRNA3 P32297 6/20 0.64
CHRNB2 P17787 5/20 0.64
CHRNA4 P43681 5/20 0.64
CHRNA1 P02708 4/20 0.64
CHRNA2 Q15822 3/20 0.64
CHRNB1 P11230 3/20 0.64
CHRNG P07510 2/20 0.64
CHRND Q07001 2/20 0.64
ALDH1A1 P00352 2/20 0.58
CHRNA7 P36544 2/20 0.58
CHRNB3 Q05901 2/20 0.58
LMNA P02545 1/20 0.58
TDP1 Q9NUW8 1/20 0.58
HTR3E A5X5Y0 1/20 0.58
PSIP1 O75475 1/20 0.58
TRPA1 O75762 1/20 0.58
HTR3B O95264 1/20 0.58
MAPT P10636 1/20 0.58
CYP2A6 P11509 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31019621 1.00 CHRNB4 (0.64) CHRNB4CHRNA3CHRNB2CHRNA4CHRNA1
SCHEMBL159159 1.00 CHRNB4 (0.64) CHRNB4CHRNA3CHRNB2CHRNA4CHRNA1
SCHEMBL159158 1.00 CHRNB4 (0.64) CHRNB4CHRNA3CHRNB2CHRNA4CHRNA1
Acetic Acid SCHEMBL27199916 0.91 CHRNB4 (0.56) CHRNB4CHRNA3CHRNB2CHRNA4CHRNA1
SCHEMBL20164036 0.91 CHRNB4 (0.56) CHRNB4CHRNA3CHRNB2CHRNA4CHRNA1
Acetic Acid SCHEMBL31344159 0.91 CHRNB4 (0.56) CHRNB4CHRNA3CHRNB2CHRNA4CHRNA1
Cadaverine Tartrate SCHEMBL30866584 0.87 BLM (0.67) CHRNB4CHRNA3CHRNB2CHRNA4CHRNA1
Lactic Acid SCHEMBL31344162 0.87 BLM (0.57) CHRNB4CHRNA3CHRNB2CHRNA4CHRNA1
L-Lactic Acid SCHEMBL27199878 0.87 BLM (0.57) CHRNB4CHRNA3CHRNB2CHRNA4CHRNA1
Lactic Acid SCHEMBL27199874 0.87 BLM (0.57) CHRNB4CHRNA3CHRNB2CHRNA4CHRNA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4683527-A1 VAPORIZABLE ALKALOID COMPOSITIONS AND METHODS OF USE THEREOF Ready Mix Naturals, LLC (US) 2026-01-28 EP claimed
US-12497381-B2 Vaporizable alkaloid compositions and methods of use thereof Ready Mix Naturals, LLC (US) 2025-12-16 US claimed
US-12478091-B2 Vaporizable alkaloid compositions and methods of use thereof Ready Mix Naturals, LLC (US) 2025-11-25 US claimed
US-20250289796-A1 COMPOSITIONS AND METHODS OF USE THEREOF Ready Mix Naturals, LLC (US) 2025-09-18 US claimed
US-12358888-B2 Vaporizable alkaloid compositions and methods of use thereof Ready Mix Naturals, LLC (US) 2025-07-15 US claimed
WO-2025096261-A1 VAPORIZABLE ALKALOID COMPOSITIONS AND METHODS OF USE THEREOF Ready Mix Naturals, LLC (US) 2025-05-08 WO claimed
WO-2025058941-A1 TOBACCO HARM REDUCTION AND PAIN RELIEF PRODUCTS AND METHODS THEREOF Ready Mix Naturals, LLC (US) 2025-03-20 WO claimed
US-20250082627-A1 TOBACCO HARM REDUCTION AND PAIN RELIEF PRODUCTS AND METHODS THEREOF Ready Mix Naturals, LLC (US) 2025-03-13 US claimed
WO-2025049141-A1 VAPORIZABLE ALKALOID COMPOSITIONS AND METHODS OF USE THEREOF Ready Mix Naturals, LLC (US) 2025-03-06 WO claimed
US-20250049096-A1 VAPORIZABLE ALKALOID COMPOSITIONS AND METHODS OF USE THEREOF Ready Mix Naturals, LLC (US) 2025-02-13 US claimed
US-20240400539-A1 VAPORIZABLE ALKALOID COMPOSITIONS AND METHODS OF USE THEREOF Ready Mix Naturals, LLC (US) 2024-12-05 US claimed
US-20240270711-A1 VAPORIZABLE ALKALOID COMPOSITIONS AND METHODS OF USE THEREOF Ready Mix Naturals, LLC (US) 2024-08-15 US claimed
WO-2024155297-A1 VAPORIZABLE ALKALOID COMPOSITIONS AND METHODS OF USE THEREOF Ready Mix Naturals, LLC (US) 2024-07-25 WO claimed
US-20240245092-A1 VAPORIZABLE ALKALOID COMPOSITIONS AND METHODS OF USE THEREOF Ready Mix Naturals, LLC (US) 2024-07-25 US claimed
US-20240246930-A1 VAPORIZABLE ALKALOID COMPOSITIONS AND METHODS OF USE THEREOF Ready Mix Naturals, LLC (US) 2024-07-25 US claimed
US-11964958-B1 Vaporizable alkaloid compositions and methods of use thereof Ready Mix Naturals, LLC (US) 2024-04-23 US claimed
EP-4683527-A1 VAPORIZABLE ALKALOID COMPOSITIONS AND METHODS OF USE THEREOF Ready Mix Naturals, LLC (US) 2026-01-28 EP disclosed
US-12497381-B2 Vaporizable alkaloid compositions and methods of use thereof Ready Mix Naturals, LLC (US) 2025-12-16 US disclosed
WO-2024155297-A1 VAPORIZABLE ALKALOID COMPOSITIONS AND METHODS OF USE THEREOF Ready Mix Naturals, LLC (US) 2024-07-25 WO disclosed
US-11964958-B1 Vaporizable alkaloid compositions and methods of use thereof Ready Mix Naturals, LLC (US) 2024-04-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240246930-A1 VAPORIZABLE ALKALOID COMPOSITIONS AND METHODS OF USE THEREOF SRM, SCLY, SMOX CHRNB4 55/4885CHRNA3 116/4885CHRNB2 98/4885
US-20240400539-A1 VAPORIZABLE ALKALOID COMPOSITIONS AND METHODS OF USE THEREOF CHRM5, NNMT, CHRM1 CHRNB4 35/4885CHRNA3 51/4885CHRNB2 82/4885
US-11964958-B1 Vaporizable alkaloid compositions and methods of use thereof SRM, SCLY, SMOX CHRNB4 55/4885CHRNA3 116/4885CHRNB2 98/4885
US-20250082627-A1 TOBACCO HARM REDUCTION AND PAIN RELIEF PRODUCTS AND METHODS THEREOF OPRK1, SYMPK, TAS2R9 CHRNB4 244/4885CHRNA3 417/4885CHRNB2 245/4885
US-20240270711-A1 VAPORIZABLE ALKALOID COMPOSITIONS AND METHODS OF USE THEREOF CHRM5, NNMT, CHRM1 CHRNB4 35/4885CHRNA3 51/4885CHRNB2 82/4885
US-20250289796-A1 COMPOSITIONS AND METHODS OF USE THEREOF OR10J3, TRPA1, TAS2R3 CHRNB4 205/4885CHRNA3 173/4885CHRNB2 389/4885
US-12358888-B2 Vaporizable alkaloid compositions and methods of use thereof SRM, SCLY, SMOX CHRNB4 55/4885CHRNA3 116/4885CHRNB2 98/4885
US-12497381-B2 Vaporizable alkaloid compositions and methods of use thereof CHRM5, NNMT, CHRM1 CHRNB4 35/4885CHRNA3 51/4885CHRNB2 82/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.