Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.53 |
| ▸ | ABL1 | P00519 | 1/20 | 0.52 |
| ▸ | CASP3 | P42574 | 1/20 | 0.51 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.51 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.51 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 7/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 6/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24542721 | 1.00 | KMT2A (0.53) | KMT2AABL1CASP3SENP8SENP7 | |
| SCHEMBL24542732 | 0.81 | EPHX2 (0.56) | KMT2AABL1MEN1ALDH1A1ADORA2A | |
| SCHEMBL24542730 | 0.80 | PDK1 (0.55) | KMT2ARAB9AMEN1ALDH1A1ADORA2A | |
| SCHEMBL24542766 | 0.78 | TRPV1 (0.54) | KMT2ARAB9AMEN1ADORA2AADORA2B | |
| SCHEMBL24542776 | 0.77 | ADORA2A (0.49) | ABL1ALDH1A1ADORA2AADORA2BMAOB | |
| SCHEMBL24543202 | 0.77 | EPHX2 (0.60) | — | |
| SCHEMBL24543109 | 0.77 | PPARA (0.54) | KMT2AMEN1ALDH1A1ADORA2AADORA2B | |
| SCHEMBL24543289 | 0.77 | ALDH1A1 (0.49) | KMT2AMEN1ALDH1A1ADORA2AADORA2B | |
| SCHEMBL2659983 | 0.77 | CASP3 (0.55) | KMT2AABL1CASP3SENP8SENP7 | |
| SCHEMBL24542749 | 0.76 | ABCC9 (0.49) | ADORA2AADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240132450-A1 | MODULATORS OF G PROTEIN-COUPLED RECEPTOR 88 | ACADIA PHARMACEUTICALS INC. | 2024-04-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240132450-A1 | MODULATORS OF G PROTEIN-COUPLED RECEPTOR 88 | GPR88, GPR65, GPR68 | KMT2A 1498/4885ABL1 994/4885CASP3 4865/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.