Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | S100A4 | P26447 | 1/20 | 0.33 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11307986 | 0.67 | AKR1C1 (0.46) | MEN1KMT2AAKR1C1LMNA | |
| SCHEMBL28487473 | 0.65 | SLC6A4 (0.46) | OPRM1OPRL1MEN1KMT2AAKR1C1 | |
| SCHEMBL21439763 | 0.64 | SLC6A4 (0.40) | OPRM1MEN1KMT2ATSHRPOLB | |
| SCHEMBL29642400 | 0.63 | PNMT (0.42) | ALDH1A1MEN1KMT2AAKR1C1TSHR | |
| SCHEMBL2184245 | 0.63 | AKR1C1 (0.64) | ALDH1A1OPRL1MEN1KMT2AAKR1C1 | |
| SCHEMBL12397137 | 0.63 | LMNA (0.50) | ALDH1A1OPRM1OPRL1MEN1KMT2A | |
| SCHEMBL11325518 | 0.63 | OPRM1 (0.41) | ALDH1A1OPRM1MEN1KMT2AAKR1C1 | |
| SCHEMBL11064099 | 0.62 | ALDH1A1 (0.46) | ALDH1A1OPRM1OPRL1MEN1KMT2A | |
| SCHEMBL11064104 | 0.62 | ALDH1A1 (0.46) | ALDH1A1OPRM1OPRL1MEN1KMT2A | |
| SCHEMBL7973167 | 0.62 | MEN1 (0.44) | ALDH1A1OPRM1OPRL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112867705-B | Opioid receptor modulators and products and methods related thereto | 埃皮欧黛公司 | 2024-08-20 | — | — | CN | disclosed |