Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 known ✓ | P22748 | 2/20 | 0.50 |
| ▸ | CA1 known ✓ | P00915 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.62 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.62 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.62 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.62 |
| ▸ | FFAR3 | O14843 | 3/20 | 0.62 |
| ▸ | CES2 | O00748 | 2/20 | 0.48 |
| ▸ | CES1 | P23141 | 2/20 | 0.48 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | CTSD | P07339 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL230831 | 0.95 | HDAC3 (0.57) | HDAC3HDAC1HDAC2HDAC8FFAR3 | |
| SCHEMBL21219180 | 0.95 | HDAC3 (0.57) | HDAC3HDAC1HDAC2HDAC8FFAR3 | |
| SCHEMBL21219182 | 0.95 | HDAC3 (0.57) | HDAC3HDAC1HDAC2HDAC8FFAR3 | |
| SCHEMBL21219170 | 0.95 | HDAC3 (0.57) | HDAC3HDAC1HDAC2HDAC8FFAR3 | |
| SCHEMBL21219172 | 0.95 | HDAC3 (0.57) | HDAC3HDAC1HDAC2HDAC8FFAR3 | |
| SCHEMBL21219178 | 0.95 | HDAC3 (0.57) | HDAC3HDAC1HDAC2HDAC8FFAR3 | |
| SCHEMBL21236946 | 0.95 | HDAC3 (0.57) | HDAC3HDAC1HDAC2HDAC8FFAR3 | |
| SCHEMBL21219168 | 0.95 | HDAC3 (0.57) | HDAC3HDAC1HDAC2HDAC8FFAR3 | |
| SCHEMBL21219174 | 0.95 | HDAC3 (0.57) | HDAC3HDAC1HDAC2HDAC8FFAR3 | |
| SCHEMBL201915 | 0.95 | HDAC3 (0.57) | HDAC3HDAC1HDAC2HDAC8FFAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117603070-A | 2-difluoro acetyl-3-dimethylamino ethyl acrylate compound, and preparation method and application thereof | 安徽泓泽新材料科技有限公司 | 2024-02-27 | — | — | CN | claimed |
| US-7741478-B2 | Salts in the preparation of cephalosporin antibiotics | ORCHID CHEMICALS & PHARMACEUTICALS LIMITED (IN) | 2010-06-22 | — | — | US | claimed |
| US-20080306256-A1 | Salts in the Preparation of Cephalosporin Antibiodies | ORCHID CHEMICALS & PHARMACEUTICALS LIMITED (IN) | 2008-12-11 | — | — | US | claimed |
| EP-1765833-A2 | NEWS SALTS IN THE PREPARATION OF CEPHALOSPORIN ANTIBIOTICS | Orchid Chemicals and Pharmaceuticals Limited (IN) | 2007-03-28 | — | — | EP | claimed |
| WO-2006006040-A2 | NEWS DIAMINE SALTS OF CEPHALOSPORIN ANTIBIOTICS AND THEIR PREPARATION | ORCHID CHEMICALS & PHARMACEUTICALS LIMITED (IN) | 2006-01-19 | — | — | WO | claimed |
| US-4517301-A | URINALYSIS, METAL SALT OF BETA-KETO ACID/ESTER | MILES LABORATORIES, INC. (US) | 1985-05-14 | — | — | US | claimed |
| CN-119822940-A | Pd-TiO2Method for preparing ketone compounds by catalyzing cellulose hydrogenation with/C supported catalyst | 华南理工大学 | 2025-04-15 | — | — | CN | disclosed |
| CN-117603070-A | 2-difluoro acetyl-3-dimethylamino ethyl acrylate compound, and preparation method and application thereof | 安徽泓泽新材料科技有限公司 | 2024-02-27 | — | — | CN | disclosed |
| EP-3305778-B1 | INHIBITORS OF PLASMA KALLIKREIN | KALVISTA PHARMACEUTICALS LTD (GB) | 2022-01-19 | — | — | EP | disclosed |
| CN-112941145-A | Inactivating reagent for enveloped viruses and pathogenic bacteria and application thereof | 郑州安图生物工程股份有限公司 | 2021-06-11 | — | — | CN | disclosed |
| CN-111638106-A | Dry chemical analysis quality control substance for urine | 吉林基蛋生物科技有限公司 | 2020-09-08 | — | — | CN | disclosed |
| CN-105143201-B | Benzyl amine derivative | 卡尔维斯塔制药有限公司 | 2019-02-22 | — | — | CN | disclosed |
| CN-105452240-B | Hete rocyclic derivatives | 卡尔维斯塔制药有限公司 | 2018-06-26 | — | — | CN | disclosed |
| US-5591872-A | REGULATION OF GENE EXPRESSION IN PSEUDOMONAS, TREATMENT OF INFECTION | THE UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 1997-01-07 | — | — | US | disclosed |
| WO-1996016005-A1 | DUAL BED XYLENE ISOMERIZATION | MOBIL OIL CORPORATION (US) | 1996-05-30 | — | — | WO | disclosed |
| EP-0039536-B1 | SHAPE SELECTIVE REACTIONS WITH ZEOLITE CATALYSTS MODIFIED WITH GROUP 1A METALS | MOBIL OIL CORPORATION (US) | 1984-09-05 | — | — | EP | disclosed |
| US-4391739-A | Zeolite catalysts modified with group IA metals | MOBIL OIL CORPORATION (US) | 1983-07-05 | — | — | US | disclosed |
| US-4329533-A | Shape selective reactions with zeolite catalysts modified with group IA metals | MOBIL OIL CORPORATION (US) | 1982-05-11 | — | — | US | disclosed |
| EP-0039536-A1 | Shape selective reactions with zeolite catalysts modified with group 1A metals | MOBIL OIL CORPORATION (US) | 1981-11-11 | — | — | EP | disclosed |
| US-4181736-A | ANALGESICS; ANTIINFLAMMATORY AGENTS; RHEUMATIC DISEASES | LABORATOIRES JACQUES LOGEAIS (FR) | 1980-01-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080306256-A1 | Salts in the Preparation of Cephalosporin Antibiodies | ABCB11, SLC10A1, NISCH | CA4 544/4885CA1 2795/4885HDAC3 3021/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.