Known targets — ChEMBL curated mechanism
GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQ
The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.50 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TGM2 | P21980 | 3/20 | 0.34 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.31 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3133989 | 0.98 | ZDHHC20 (0.52) | ZDHHC20ZDHHC2TSHRMAPK1ALDH1A1 | |
| Bromide SCHEMBL28656527 | 0.96 | ZDHHC20 (0.50) | ZDHHC20ZDHHC2TSHRMAPK1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL137143 | 0.96 | ZDHHC20 (0.50) | ZDHHC20ZDHHC2TSHRMAPK1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL5850624 | 0.96 | ZDHHC20 (0.50) | ZDHHC20ZDHHC2TSHRMAPK1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL27707483 | 0.92 | ZDHHC20 (0.47) | ZDHHC20ZDHHC2TSHRMAPK1ALDH1A1 | |
| Acrylamide SCHEMBL713794 | 0.89 | ZDHHC20 (0.44) | ZDHHC20ZDHHC2TSHRMAPK1ALDH1A1 | |
| Sulfuric Acid SCHEMBL6478258 | 0.89 | ZDHHC20 (0.44) | ZDHHC20ZDHHC2TSHRMAPK1ALDH1A1 | |
| Water SCHEMBL2355003 | 0.88 | ZDHHC20 (0.56) | ZDHHC20ZDHHC2TSHRMAPK1ALDH1A1 | |
| SCHEMBL29003384 | 0.87 | ZDHHC20 (0.51) | ZDHHC20ZDHHC2TSHRMAPK1ALDH1A1 | |
| SCHEMBL192702 | 0.86 | ZDHHC20 (0.58) | ZDHHC20ZDHHC2TSHRMAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12618000-B2 | Friction reduction of acidic treatment fluids | HALLIBURTON ENERGY SERVICES, INC. (US) | 2026-05-05 | — | — | US | disclosed |
| US-20260071533-A1 | TREATMENT FLUID SELECTION | HALLIBURTON ENERGY SERVICES, INC. (US) | 2026-03-12 | — | — | US | disclosed |
| US-12247165-B2 | Anti-syneresis agents for fracturing operations | HALLIBURTON ENERGY SERVICES, INC. (US) | 2025-03-11 | — | — | US | disclosed |
| US-20250075122-A1 | ADDITIVES TO PREVENT THERMAL THINNING IN POLYMER GEL SYSTEMS | HALLIBURTON ENERGY SERVICES, INC. (US) | 2025-03-06 | — | — | US | disclosed |
| US-20250051634-A1 | ANTI-SYNERESIS AGENTS FOR FRACTURING OPERATIONS | HALLIBURTON ENERGY SERVICES, INC. (US) | 2025-02-13 | — | — | US | disclosed |
| US-20250051635-A1 | FRICTION REDUCTION OF ACIDIC TREATMENT FLUIDS | HALLIBURTON ENERGY SERVICES, INC. (US) | 2025-02-13 | — | — | US | disclosed |
| WO-2025006003-A1 | FRICTION REDUCTION OF ACIDIC TREATMENT FLUIDS | HALLIBURTON ENERGY SERVICES, INC. (US) | 2025-01-02 | — | — | WO | disclosed |
| US-12139667-B1 | Friction reduction of acidic treatment fluids | HALLIBURTON ENERGY SERVICES, INC. (US) | 2024-11-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260071533-A1 | TREATMENT FLUID SELECTION | PLG, SOST, CSTB | ZDHHC20 1858/4885ZDHHC2 2501/4885TSHR 1255/4885 |
| US-12618000-B2 | Friction reduction of acidic treatment fluids | GFER, FGB, NSF | ZDHHC20 4132/4885ZDHHC2 4203/4885TSHR 1564/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.