Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 16/20 | 0.66 |
| ▸ | NPC1 | O15118 | 14/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 14/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 14/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.66 |
| ▸ | HPGD | P15428 | 12/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 8/20 | 0.66 |
| ▸ | TP53 | P04637 | 6/20 | 0.66 |
| ▸ | MAPT | P10636 | 10/20 | 0.63 |
| ▸ | NFKB1 | P19838 | 5/20 | 0.63 |
| ▸ | NFKB2 | Q00653 | 5/20 | 0.63 |
| ▸ | RELA | Q04206 | 5/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.59 |
| ▸ | CASP3 | P42574 | 4/20 | 0.58 |
| ▸ | SENP7 | Q9BQF6 | 4/20 | 0.58 |
| ▸ | SENP6 | Q9GZR1 | 4/20 | 0.58 |
| ▸ | SENP8 | Q96LD8 | 3/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.58 |
| ▸ | MMP2 | P08253 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12643200 | 0.89 | RAB9A (0.69) | RAB9ANPC1KDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL2491813 | 0.83 | RAB9A (0.69) | RAB9ANPC1KDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL14947173 | 0.82 | ALDH1A1 (0.96) | RAB9ANPC1KDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL474369 | 0.81 | RAB9A (0.82) | RAB9ANPC1KDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL31154077 | 0.81 | RAB9A (0.82) | RAB9ANPC1KDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL22103734 | 0.81 | NPC1 (0.81) | RAB9ANPC1KDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL2245161 | 0.81 | RAB9A (0.66) | RAB9ANPC1KDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL15047797 | 0.80 | ALDH1A1 (0.93) | RAB9ANPC1KDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL3288386 | 0.80 | ALDH1A1 (1.00) | RAB9ANPC1KDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL13171393 | 0.78 | ALOX5 (0.78) | RAB9ANPC1KDM4ESMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100004301-A1 | Benzoxazoles Useful in the Treatment of Inflammation | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-01-07 | — | — | US | disclosed |
| EP-2102177-A1 | BENZOXAZOLES USEFUL IN THE TREATMENT OF INFLAMMATION | Boehringer Ingelheim International GmbH (DE) | 2009-09-23 | — | — | EP | disclosed |
| WO-2008071944-A1 | BENZOXAZOLES USEFUL IN THE TREATMENT OF INFLAMMATION | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-06-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100004301-A1 | Benzoxazoles Useful in the Treatment of Inflammation | IL4I1, EPX, IL4 | RAB9A 3680/4885NPC1 4501/4885KDM4E 1264/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.