Perchlorate

Perchlorate

SCHEMBL3135944

Cc1ccc(-c2cccc(S)c2-c2ccc(C)cc2)cc1.[O-][Cl+3]([O-])([O-])O

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ENPP1 P22413 1/20 0.39
MEN1 O00255 1/20 0.36
POLB P06746 1/20 0.36
KMT2A Q03164 1/20 0.36
PTGS2 P35354 3/20 0.35
PTGS1 P23219 1/20 0.34
GPR84 Q9NQS5 1/20 0.33
MMP2 P08253 1/20 0.32
MMP9 P14780 1/20 0.32
EDNRB P24530 1/20 0.31
EDNRA P25101 1/20 0.31
LMNA P02545 2/20 0.31
MAPK1 P28482 2/20 0.31
TDP1 Q9NUW8 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
NPC1 O15118 2/20 0.31
RAB9A P51151 2/20 0.31
HPRT1 P00492 1/20 0.31
RCE1 Q9Y256 1/20 0.31
KDR P35968 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL482553 0.91 ENPP1 (0.44) ENPP1MEN1POLBKMT2APTGS2
Iodide SCHEMBL7090862 0.89 ENPP1 (0.43) ENPP1MEN1POLBKMT2APTGS2
Bromide SCHEMBL3139959 0.89 ENPP1 (0.43) ENPP1MEN1POLBKMT2APTGS2
Perchlorate SCHEMBL3126960 0.84 ABL1 (0.40) MEN1POLBKMT2AMMP2MMP9
SCHEMBL3144542 0.83 LMNA (0.44) MEN1POLBKMT2APTGS2PTGS1
Perchlorate SCHEMBL3132388 0.83 PTGS2 (0.38) POLBPTGS2PTGS1GPR84MMP2
Perchlorate SCHEMBL3140978 0.83 ENPP1 (0.40) ENPP1PTGS2PTGS1GPR84KDR
Perchlorate SCHEMBL3135201 0.82 HDAC4 (0.46) ENPP1KMT2APTGS2PTGS1GPR84
Perchlorate SCHEMBL3139518 0.82 GPR84 (0.36) MEN1KMT2AGPR84LMNAL3MBTL1
Perchlorate SCHEMBL3132416 0.80 KIF11 (0.40) ENPP1MEN1POLBKMT2AMMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7642368-B2 for use as acid generator in semiconductor manufacture; triarylsulfonium salt having a structure that only one aromatic ring of three is different, in a high yield and by-product inhibition; reacting a diaryl sulfoxide with an aryl Grignard reagent in presence of chlorotrialkylsilane and strong acid WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2010-01-05 US disclosed
US-20070083060-A1 for use as acid generator in semiconductor manufacture; triarylsulfonium salt having a structure that only one aromatic ring of three is different, in a high yield and by-product inhibition; reacting a diaryl sulfoxide with an aryl Grignard reagent in presence of chlorotrialkylsilane and strong acid FUJIFILM WAKO PURE CHEMICAL CORPORATION (JP) 2007-04-12 US disclosed
EP-1676835-A1 PROCESS FOR PRODUCING TRIARYLSULFONIUM SALT Wako Pure Chemical Industries, Ltd. (JP) 2006-07-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070083060-A1 for use as acid generator in semiconductor manufacture; triarylsulfonium salt having a structure that only one aromatic ring of three is different, in a high yield and by-product inhibition; reacting a diaryl sulfoxide with an aryl Grignard reagent in presence of chlorotrialkylsilane and strong acid ARSA, HAO2, HAO1 ENPP1 3425/4885MEN1 3088/4885POLB 3028/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.