SCHEMBL3137897

SCHEMBL3137897

O=C(O)Oc1cc(OC(=O)O)oc(=O)c1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 9/20 0.37
GAA P10253 8/20 0.37
GLA P06280 7/20 0.37
ALDH1A1 P00352 7/20 0.37
MAPT P10636 6/20 0.37
CASP1 P29466 3/20 0.37
CASP7 P55210 3/20 0.37
HSD17B10 Q99714 3/20 0.37
TSHR P16473 1/20 0.37
LMNA P02545 1/20 0.36
TP53 P04637 1/20 0.36
MAPK1 P28482 1/20 0.36
HTT P42858 1/20 0.36
CA9 Q16790 7/20 0.35
CA12 O43570 6/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA3 P07451 1/20 0.35
CA4 P22748 1/20 0.35
CA5A P35218 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL377105 0.74 ALOX15 (0.39) ALOX15SMN1; SMN2
SCHEMBL322525 0.72 LMNA (0.40) KDM4EGAAALDH1A1MAPTHSD17B10
SCHEMBL9901826 0.67 KDM4E (0.54) KDM4EGAAGLAALDH1A1MAPT
SCHEMBL7258244 0.66 KDM4E (0.36) KDM4EGAAALDH1A1MAPTTSHR
SCHEMBL377017 0.66 KMT2A (0.32) ALDH1A1TSHRTP53TDP1KMT2A
SCHEMBL1001721 0.66 RXRA (0.42) KDM4EGAAMAPTHSD17B10LMNA
SCHEMBL9574620 0.65 GPR35 (0.32) KDM4ETDP1KMT2A
SCHEMBL2486195 0.65 CHRNA4 (0.32) ALDH1A1MAPTPOLB
SCHEMBL1730357 0.64 CYP3A4 (0.43) KDM4EALDH1A1MAPTHSD17B10LMNA
SCHEMBL1128210 0.64 CA12 (0.46) ALDH1A1MAPTHSD17B10LMNAMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1099755-B1 NOVEL GENE AND TRANSFORMANT CARRYING THE SAME COSMO RES INST (JP) 2004-09-22 EP claimed
EP-1092741-B1 POLYESTER AND PROCESS FOR PRODUCING THE SAME COSMO RES INST (JP) 2003-09-10 EP claimed
US-20100004469-A1 ANTIMICROBIAL AGENTS AND MICROBICIDAL AGENTS KABUSHIKI KAISHA TOYOTA JIDOSHOKKI (JP) 2010-01-07 US disclosed
EP-2103213-A1 ANTIBACTERIAL AGENT AND BACTERICIDAL AGENT Kabushiki Kaisha Toyota Jidoshokki (JP) 2009-09-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100004469-A1 ANTIMICROBIAL AGENTS AND MICROBICIDAL AGENTS MPO, ARG1, ARG2 KDM4E 4170/4885GAA 642/4885GLA 823/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.