Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31388683 | 1.00 | MEN1 (0.42) | MEN1KMT2AKEAP1NPC1RAB9A | |
| SCHEMBL7436508 | 0.84 | ALDH1A1 (0.46) | KMT2AKEAP1ALDH1A1TDP1FFAR1 | |
| SCHEMBL31388685 | 0.77 | ALDH1A1 (0.41) | KEAP1ALDH1A1FFAR1 | |
| SCHEMBL16174891 | 0.76 | GLA (0.45) | NPC1RAB9AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL10191376 | 0.74 | ALDH1A1 (0.50) | KEAP1NPC1ALDH1A1TDP1FFAR1 | |
| SCHEMBL11730482 | 0.74 | KEAP1 (0.53) | KEAP1NPC1ALDH1A1TDP1FFAR1 | |
| SCHEMBL12290424 | 0.71 | NPSR1 (0.41) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL5642127 | 0.70 | BACE1 (0.42) | ALDH1A1FFAR1 | |
| SCHEMBL9869709 | 0.70 | CASP3 (0.41) | MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL31388686 | 0.69 | SLC25A5 (0.41) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250107525-A1 | CARBOXYLIC ACID-DERIVED KETO-DIESTERS AND USES THEREOF | UNIVERSITY OF MISSISSIPPI | 2025-04-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250107525-A1 | CARBOXYLIC ACID-DERIVED KETO-DIESTERS AND USES THEREOF | BCKDK, KYAT1, KYAT3 | MEN1 4609/4885KMT2A 541/4885KEAP1 1182/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.