Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.45 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.42 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 6/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | PPARD | Q03181 | 2/20 | 0.38 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.38 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL246134 | 0.85 | EPHX1 (0.45) | MEN1KMT2AKDM4EALDH1A1TSHR | |
| SCHEMBL1983184 | 0.85 | EPHX1 (0.45) | MEN1KMT2AKDM4EALDH1A1TSHR | |
| SCHEMBL6064920 | 0.81 | EPHX1 (0.53) | PLA2G2AKDM4EALDH1A1 | |
| SCHEMBL2012446 | 0.80 | MMP1 (0.39) | MEN1KMT2AKDM4EALDH1A1TDP1 | |
| SCHEMBL15541398 | 0.76 | CTH (0.40) | PLA2G2AMEN1KMT2AMAPTSLC6A5 | |
| SCHEMBL15541397 | 0.76 | CTH (0.40) | PLA2G2AMEN1KMT2AMAPTSLC6A5 | |
| Acrylic Acid SCHEMBL6129258 | 0.76 | ZDHHC20 (0.45) | MEN1KMT2AEPHX2KDM4EALDH1A1 | |
| SCHEMBL2634811 | 0.76 | ALDH1A1 (0.35) | MEN1KMT2AKDM4EALDH1A1TDP1 | |
| SCHEMBL9451088 | 0.76 | ALDH1A1 (0.35) | MEN1KMT2AKDM4EALDH1A1TDP1 | |
| SCHEMBL432886 | 0.76 | CASP2 (0.46) | PLA2G4APLA2G2AEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100069544-A1 | HYDROGEL CONTACT LENS COMPRISING A POLYMER COMPRISING A CARBOXY BETAINE ESTER MONOMER | PROCORNEA HOLDING B.V. | 2010-03-18 | — | — | US | disclosed |
| EP-2087397-A1 | HYDROGEL CONTACT LENS COMPRISING A POLYMER COMPRISING A CARBOXY BETAINE ESTER MONOMER | Procornea Holding B.V. (NL) | 2009-08-12 | — | — | EP | disclosed |
| WO-2008066381-A1 | HYDROGEL CONTACT LENS COMPRISING A POLYMER COMPRISING A CARBOXY BETAINE ESTER MONOMER | PROCORNEA HOLDING B.V. (NL) | 2008-06-05 | — | — | WO | disclosed |
| WO-2002064665-A1 | HYDROPHILIC POLYMER MATERIAL COMPRISING A POLYORGANOSILOXANE CROSSLINKED MATRIX AND METHOD FOR MAKING SAME | OCULAR SCIENCES S.A.S. (FR) | 2002-08-22 | — | — | WO | disclosed |
| US-6372815-B1 | IMMOBILIZED WATER SWELLING POLYMER | COOPERVISION INTERNATIONAL LIMITED (GB) | 2002-04-16 | — | — | US | disclosed |
| EP-1036102-A1 | METHOD FOR MAKING A TRANSPARENT POLYMER MATERIAL RESISTANT TO PROTEIN DEPOSIT, MATERIAL OBTAINED BY SAID METHOD, CONTACT LENSES AND INTRAOCULAR IMPLANTS MADE OF SAID MATERIAL | ESSILOR INTERNATIONAL COMPAGNIE GENERALE D'OPTIQUE (FR) | 2000-09-20 | — | — | EP | disclosed |
| WO-1999029750-A1 | METHOD FOR MAKING A TRANSPARENT POLYMER MATERIAL RESISTANT TO PROTEIN DEPOSIT, MATERIAL OBTAINED BY SAID METHOD, CONTACT LENSES AND INTRAOCULAR IMPLANTS MADE OF SAID MATERIAL | ESSILOR INTERNATIONAL COMPAGNIE GENERALE D'OPTIQUE (FR) | 1999-06-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100069544-A1 | HYDROGEL CONTACT LENS COMPRISING A POLYMER COMPRISING A CARBOXY BETAINE ESTER MONOMER | CRYAA, CRYZ, CRYAB | ADRA1A 2194/4885PLA2G4A 4495/4885PRMT1 234/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.