SCHEMBL3140759

SCHEMBL3140759

Cc1cc(C(F)(C(F)(F)F)C(F)(F)F)cc(C)c1I

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
AGBL2 Q5U5Z8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16703694 0.85
SCHEMBL22927041 0.81 RAPGEF4 (0.34) AGBL2
SCHEMBL531949 0.79 RAPGEF4 (0.42) AGBL2
SCHEMBL5355782 0.75 PTGS2 (0.31)
SCHEMBL698408 0.75 POLB (0.52)
SCHEMBL5355232 0.75 ESR1 (0.48)
SCHEMBL5360962 0.75 CYP3A4 (0.44)
SCHEMBL3137826 0.75 GAA (0.33)
SCHEMBL1842024 0.74 PGK1 (0.41)
SCHEMBL20868551 0.74 PGK1 (0.46)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10150737-B2 Compounds for controlling arthropods BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2018-12-11 US disclosed
US-9758485-B2 Compounds for controlling arthropods BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2017-09-12 US disclosed
US-20160297765-A1 NOVEL COMPOUNDS FOR CONTROLLING ARTHROPODS ELANCO ANIMAL HEALTH GMBH (DE) 2016-10-13 US disclosed
US-20160278379-A1 NOVEL COMPOUNDS FOR CONTROLLING ARTHROPODS ELANCO ANIMAL HEALTH GMBH (DE) 2016-09-29 US disclosed
EP-3066079-A1 SUBSTITUTED BENZAMIDES FOR TREATING ARTHROPODES Bayer CropScience Aktiengesellschaft (DE) 2016-09-14 EP disclosed
EP-3066080-A1 SUBSTITUTED BENZAMIDES FOR THE TREATMENT OF ARTHROPODS Bayer CropScience Aktiengesellschaft (DE) 2016-09-14 EP disclosed
WO-2015067647-A1 SUBSTITUTED BENZAMIDES FOR THE TREATMENT OF ARTHROPODS BAYER CROPSCIENCE AG (DE) 2015-05-14 WO disclosed
WO-2015067646-A1 SUBSTITUTED BENZAMIDES FOR TREATING ARTHROPODES BAYER CROPSCIENCE AG (DE) 2015-05-14 WO disclosed
US-8466180-B2 Insecticidal compounds SYNGENTA CROP PROTECTION LLC (US) 2013-06-18 US disclosed
US-8466180-B2 Insecticidal compounds SYNGENTA CROP PROTECTION LLC (US) 2013-06-18 US disclosed
US-8466180-B2 Insecticidal compounds SYNGENTA CROP PROTECTION LLC (US) 2013-06-18 US disclosed
US-20100076078-A1 INSECTICIDAL COMPOUNDS SYNGENTA CORP PROTECTION, INC. (US) 2010-03-25 US disclosed
US-20100076078-A1 INSECTICIDAL COMPOUNDS SYNGENTA CORP PROTECTION, INC. (US) 2010-03-25 US disclosed
CN-101578260-A Insecticidal compounds SYNGENTA PARTICIPATIONS AG (CH) 2009-11-11 CN disclosed
EP-2069287-A1 INSECTICIDAL COMPOUNDS Syngeta Participations AG (CH) 2009-06-17 EP disclosed
WO-2008031534-A1 INSECTICIDAL COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2008-03-20 WO disclosed
US-7169955-B2 Perfluoroisopropylbenzene derivative NIHON NOHYAKU CO., LTD. (JP) 2007-01-30 US disclosed
US-20050113567-A1 Perfluoroisopropylbenzene derivative NIHON NOHYAKU CO., LTD. (JP) 2005-05-26 US disclosed
US-20030187233-A1 PERFLUOROISOPROPYBENZENE DERIVATIVE NIHON NOHYAKU CO., LTD. (JP) 2003-10-02 US disclosed
EP-1253128-A1 PERFLUOROISOPROPYLBENZENE DERIVATIVES Nihon Nohyaku Co., Ltd. (JP) 2002-10-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030187233-A1 PERFLUOROISOPROPYBENZENE DERIVATIVE AFF1, CBR1, RER1 AGBL2 3041/4885
US-20100076078-A1 INSECTICIDAL COMPOUNDS ACHE, CHRM1, CHRM2 AGBL2 3604/4885
US-20160278379-A1 NOVEL COMPOUNDS FOR CONTROLLING ARTHROPODS CYP4X1, CYP4B1, SERPINB6 AGBL2 2104/4885
US-10150737-B2 Compounds for controlling arthropods SERPINB6, CYP4X1, C1S AGBL2 2349/4885
US-20050113567-A1 Perfluoroisopropylbenzene derivative FFAR3, CBR3, HCAR3 AGBL2 4000/4885
US-20160297765-A1 NOVEL COMPOUNDS FOR CONTROLLING ARTHROPODS CYP4X1, CYP4B1, SERPINB6 AGBL2 2104/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.