Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.47 |
| ▸ | GP6 | Q9HCN6 | 2/20 | 0.44 |
| ▸ | XDH | P47989 | 1/20 | 0.44 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.43 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.41 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | AKT1 | P31749 | 1/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3778977 | 0.99 | SLC22A12 (0.47) | SLC22A12GP6XDHEGLN1CYSLTR2 | |
| SCHEMBL3150987 | 0.91 | XDH (0.46) | SLC22A12XDHALDH1A1AKT1 | |
| Hydrochloric Acid SCHEMBL3772959 | 0.90 | XDH (0.45) | SLC22A12XDHALDH1A1AKT1 | |
| Hydrochloric Acid SCHEMBL3774374 | 0.82 | IDO1 (0.40) | SLC22A12GP6XDHEGLN1ALDH1A1 | |
| SCHEMBL3150645 | 0.80 | CYP11B1 (0.47) | — | |
| SCHEMBL3142735 | 0.80 | S1PR1 (0.38) | SLC22A12XDH | |
| SCHEMBL3147229 | 0.80 | CHRNB2 (0.49) | — | |
| SCHEMBL3147306 | 0.79 | INPPL1 (0.43) | SLC22A12XDHAKT1 | |
| SCHEMBL3137054 | 0.79 | CYP11B2 (0.39) | AKT1 | |
| SCHEMBL3146014 | 0.79 | CHRNB1 (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1979321-B9 | NOVEL PYRIDINYLAMINOALKYLENE- AND PYRIDINYLOXYALKYLENE-CYCLOPROPANAMINES, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SERVIER LAB (FR) | 2010-02-17 | — | — | EP | disclosed |
| EP-1979321-B1 | NOVEL PYRIDINYLAMINOALKYLENE- AND PYRIDINYLOXYALKYLENE-CYCLOPROPANAMINES, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SERVIER LAB (FR) | 2009-07-29 | — | — | EP | disclosed |