Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.81 |
| ▸ | LMNA | P02545 | 3/20 | 0.81 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.81 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.58 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.54 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.54 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 6/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Octisalate SCHEMBL28468920 | 0.94 | LMNA (0.72) | ALDH1A1LMNAMAPK1CYP3A4CA2 | |
| Octocrylene SCHEMBL3216088 | 0.93 | ALDH1A1 (0.82) | ALDH1A1LMNAMAPK1CYP3A4CA2 | |
| Octocrylene SCHEMBL38659364 | 0.90 | ALDH1A1 (0.71) | ALDH1A1LMNAMAPK1CYP3A4CA2 | |
| Octocrylene SCHEMBL16483 | 0.90 | ALDH1A1 (1.00) | ALDH1A1LMNAMAPK1CYP3A4CA2 | |
| Octocrylene SCHEMBL1769135 | 0.90 | ALDH1A1 (1.00) | ALDH1A1LMNAMAPK1CYP3A4CA2 | |
| Octocrylene SCHEMBL28123035 | 0.89 | ALDH1A1 (0.98) | ALDH1A1LMNAMAPK1CYP3A4CA2 | |
| Octocrylene SCHEMBL19583477 | 0.88 | ALDH1A1 (0.95) | ALDH1A1LMNAMAPK1CYP3A4CA2 | |
| Octocrylene SCHEMBL29169910 | 0.87 | ALDH1A1 (0.67) | ALDH1A1LMNAMAPK1CYP3A4CA2 | |
| SCHEMBL16806267 | 0.87 | ALDH1A1 (0.89) | ALDH1A1LMNAMAPK1CYP3A4CA2 | |
| Octocrylene SCHEMBL818975 | 0.87 | ALDH1A1 (0.93) | ALDH1A1LMNAMAPK1CYP3A4CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1474099-B1 | LOW-VISCOSITY, SPRAYABLE W/O EMULSIONS | BEIERSDORF AG (DE) | 2009-09-09 | — | — | EP | claimed |
| EP-1474099-A1 | LOW-VISCOSITY, SPRAYABLE W/O EMULSIONS | Beiersdorf AG (DE) | 2004-11-10 | — | — | EP | claimed |
| EP-1443884-A1 | COSMETIC OR DERMATOLOGICAL IMPREGNATED TISSUES | Beiersdorf AG (DE) | 2004-08-11 | — | — | EP | claimed |
| WO-2003039492-A1 | COSMETIC OR DERMATOLOGICAL IMPREGNATED TISSUES | BEIERSDORF AG (DE) | 2003-05-15 | — | — | WO | claimed |
| WO-2003039508-A1 | LOW-VISCOSITY, SPRAYABLE W/O EMULSIONS | BEIERSDORF AG (DE) | 2003-05-15 | — | — | WO | claimed |
| EP-2925293-B1 | TETRACYCLINE TOPICAL FORMULATIONS, PREPARATION AND USES THEREOF | HOVIONE SCIENTIA LTD (IE) | 2017-08-02 | — | — | EP | disclosed |
| US-20170182071-A1 | TETRACYCLINE TOPICAL FORMULATIONS, PREPARATION AND USES THEREOF IN TREATING AN OCULAR CONDITION | HOVIONE INTERNATIONAL LTD. (HK) | 2017-06-29 | — | — | US | disclosed |
| US-9592246-B2 | Tetracycline topical formulations, preparation and uses thereof | HOVIONE INTERNATIONAL LTD. (HK) | 2017-03-14 | — | — | US | disclosed |
| EP-2925293-A1 | TETRACYCLINE TOPICAL FORMULATIONS, PREPARATION AND USES THEREOF | Hovione Scientia Limited (IE) | 2015-10-07 | — | — | EP | disclosed |
| WO-2014083311-A1 | TETRACYCLINE TOPICAL FORMULATIONS, PREPARATION AND USES THEREOF | HOVIONE INTERNATIONAL LTD (CN) | 2014-06-05 | — | — | WO | disclosed |
| US-20140147504-A1 | TETRACYCLINE TOPICAL FORMULATIONS, PREPARATION AND USES THEREOF | HOVIONE INTERNATIONAL LTD. (HK) | 2014-05-29 | — | — | US | disclosed |
| EP-1669061-B9 | Foam forming systems devoid of propellant gas, the production as well as the cosmetic, dermatological and hygienical use thereof | MERZ PHARMA GMBH & CO KGAA (DE) | 2010-03-10 | — | — | EP | disclosed |
| EP-1669061-B1 | Foam forming systems devoid of propellant gas, the production as well as the cosmetic, dermatological and hygienical use thereof | MERZ PHARMA GMBH & CO KGAA (DE) | 2009-11-18 | — | — | EP | disclosed |
| EP-1752137-A2 | Hydrophilic or ambiphilic bases and compositions | Merz Pharma GmbH & Co.KGaA (DE) | 2007-02-14 | — | — | EP | disclosed |
| EP-1669061-A1 | Foam forming systems devoid of propellant gas, the production as well as the cosmetic, dermatological and hygienical use thereof | Merz Pharma GmbH & Co. KGaA (DE) | 2006-06-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140147504-A1 | TETRACYCLINE TOPICAL FORMULATIONS, PREPARATION AND USES THEREOF | TET1, TUBB6, TET3 | ALDH1A1 3674/4885LMNA 2039/4885MAPK1 3189/4885 |
| US-20170182071-A1 | TETRACYCLINE TOPICAL FORMULATIONS, PREPARATION AND USES THEREOF IN TREATING AN OCULAR CONDITION | TCOF1, SHH, TUBB6 | ALDH1A1 3532/4885LMNA 2127/4885MAPK1 2654/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.