Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | BACE1 | P56817 | 2/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 5/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.39 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31649113 | 0.90 | TACR1 (0.39) | SIGMAR1TACR1ALDH1A1KDM4E | |
| SCHEMBL31649336 | 0.85 | TACR1 (0.47) | TACR1HSD11B1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL31649427 | 0.83 | ALDH1A1 (0.46) | SIGMAR1TACR1NPC1ALDH1A1KDM4E | |
| SCHEMBL31649206 | 0.83 | OPRM1 (0.39) | SIGMAR1HSD11B1ALDH1A1KDM4EOPRM1 | |
| SCHEMBL31649442 | 0.83 | PRSS1 (0.41) | TACR1HSD11B1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL31649309 | 0.80 | ACHE (0.43) | ACHETACR1ALDH1A1OPRM1 | |
| SCHEMBL31649407 | 0.79 | ALDH1A1 (0.41) | TACR1HSD11B1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL31649269 | 0.75 | DPP4 (0.49) | TACR1HSD11B1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL31649413 | 0.75 | DPP4 (0.49) | TACR1HSD11B1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL31649391 | 0.75 | ACE (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025132943-A1 | DECAHYDROQUINOLINES AS DNA POLYMERASE THETA INHIBITORS | BREAKPOINT THERAPEUTICS GMBH (DE) | 2025-06-26 | — | — | WO | disclosed |