Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 10/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ACE | P12821 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | FAP | Q12884 | 1/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31649442 | 0.86 | PRSS1 (0.41) | TACR1NPC1RAB9ASMN1; SMN2HSD11B1 | |
| SCHEMBL31649444 | 0.85 | BCHE (0.41) | TACR1NPC1RAB9ASMN1; SMN2HSD11B1 | |
| SCHEMBL31649309 | 0.84 | ACHE (0.43) | TACR1MEN1KMT2A | |
| SCHEMBL31649427 | 0.83 | ALDH1A1 (0.46) | TACR1NPC1KDM4EMEN1LMNA | |
| SCHEMBL31649113 | 0.83 | TACR1 (0.39) | TACR1KDM4EMEN1KMT2AEPHX2 | |
| SCHEMBL31649407 | 0.82 | ALDH1A1 (0.41) | TACR1NPC1RAB9ASMN1; SMN2HSD11B1 | |
| SCHEMBL31649065 | 0.81 | TACR1 (0.39) | TACR1NPC1RAB9ASMN1; SMN2HSD11B1 | |
| SCHEMBL31649269 | 0.78 | DPP4 (0.49) | TACR1NPC1RAB9ASMN1; SMN2HSD11B1 | |
| SCHEMBL31649413 | 0.78 | DPP4 (0.49) | TACR1NPC1RAB9ASMN1; SMN2HSD11B1 | |
| SCHEMBL31649391 | 0.78 | ACE (0.50) | ACEKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025132943-A1 | DECAHYDROQUINOLINES AS DNA POLYMERASE THETA INHIBITORS | BREAKPOINT THERAPEUTICS GMBH (DE) | 2025-06-26 | — | — | WO | disclosed |