Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 2/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | FAP | Q12884 | 1/20 | 0.37 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.37 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | CPT2 | P23786 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31649221 | 0.87 | HSD11B1 (0.40) | HSD11B1NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL31649206 | 0.85 | OPRM1 (0.39) | HSD11B1DPP4DPP9ALDH1A1SLC6A2 | |
| SCHEMBL31649462 | 0.85 | ACHE (0.43) | HSD11B1DPP4FAPDPP8DPP9 | |
| SCHEMBL31649151 | 0.85 | ACHE (0.43) | HSD11B1DPP4FAPDPP8DPP9 | |
| SCHEMBL31649158 | 0.83 | ALDH1A1 (0.46) | TACR1NPC1ALDH1A1MEN1KMT2A | |
| SCHEMBL31649185 | 0.83 | ALDH1A1 (0.46) | TACR1NPC1ALDH1A1MEN1KMT2A | |
| SCHEMBL31649409 | 0.83 | RORC (0.40) | HSD11B1NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL31649304 | 0.83 | NPC1 (0.39) | TACR1HSD11B1DPP4FAPDPP8 | |
| SCHEMBL31649296 | 0.83 | HTR2A (0.40) | HSD11B1ALDH1A1MEN1KMT2ASIGMAR1 | |
| SCHEMBL31649336 | 0.81 | TACR1 (0.47) | TACR1HSD11B1DPP4FAPDPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025132943-A1 | DECAHYDROQUINOLINES AS DNA POLYMERASE THETA INHIBITORS | BREAKPOINT THERAPEUTICS GMBH (DE) | 2025-06-26 | — | — | WO | disclosed |