SCHEMBL3167403

SCHEMBL3167403

N#CCCNC1CCCCC1

nearest known ligand 0.40

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 6/20 0.40
KDM4E B2RXH2 2/20 0.40
RAD52 P43351 1/20 0.40
CXCR4 P61073 5/20 0.39
CXCL12 P48061 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.38
DPP8 Q6V1X1 1/20 0.38
DPP9 Q86TI2 1/20 0.38
ALDH1A1 P00352 1/20 0.36
HSD17B10 Q99714 1/20 0.36
HRH3 Q9Y5N1 2/20 0.36
TAAR1 Q96RJ0 1/20 0.36
DPP7 Q9UHL4 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6160369 1.00 DPP4 (0.40) DPP4KDM4ERAD52CXCR4CXCL12
SCHEMBL2751529 0.98 SMN1; SMN2 (0.39) DPP4KDM4ERAD52CXCR4CXCL12
SCHEMBL6977767 0.93
Alcohol SCHEMBL29090208 0.90 DPP4 (0.39) DPP4KDM4ERAD52CXCR4CXCL12
SCHEMBL1190555 0.88
SCHEMBL5831087 0.88 JAK1 (0.39) DPP4SMN1; SMN2DPP8DPP9ALDH1A1
SCHEMBL21089261 0.82 JAK1 (0.36) DPP4ALDH1A1HSD17B10
SCHEMBL9452822 0.80 CXCR4 (0.34) DPP4KDM4ERAD52CXCR4CXCL12
SCHEMBL7522442 0.79 ALDH1A1 (0.32) ALDH1A1
SCHEMBL6050954 0.79 ALDH1A1 (0.32) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 122 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025119782-A1 METHOD FOR THE MANUFACTURE OF NEW AMINE EVONIK OPERATIONS GMBH (DE) 2025-06-12 WO claimed
US-20250075147-A1 FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING NEW FLAVOR AND FRAGRANCE INGREDIENTS OSMO LABS, PBC 2025-03-06 US claimed
CN-114591200-B Preparation method of dicyanoethyl tertiary amine 万华化学集团股份有限公司 2023-07-14 CN claimed
CN-114890913-B Method for preparing dicyanoethyl cyclohexylamine 万华化学集团股份有限公司 2023-05-26 CN claimed
CN-114890913-A Method for preparing dicyanoethyl cyclohexylamine 万华化学集团股份有限公司 2022-08-12 CN claimed
CN-114591200-A Preparation method of dicyanoethyl tertiary amine 万华化学集团股份有限公司 2022-06-07 CN claimed
US-20090264412-A1 Combination Therapy Using An 11beta-Hydroxysteroid Dehydrogenase Type 1 Inhibitor And A Glucocorticoid Receptor Agonist To Minimize The Side Effects Associated With Glucocorticoid Receptor Agonist Therapy HIGH POINT PHARMACEUTICALS, LLC (US) 2009-10-22 US claimed
US-20090137574-A1 Combination Therapy Using an 11Beta-Hydroxysteroid Dehydrogenase Type 1 Inhibitor and an Antihypertensive Agent for the Treatment of Metabolic Syndrome and Related Diseases and Disorders NOVO NORDISK A/S (DK) 2009-05-28 US claimed
US-20090048466-A1 PROCESS FOR PREPARING AMINES BY CONDITIONING THE CATALYST WITH AMMONIA EVONIK DEGUSSA GMBH (DE) 2009-02-19 US claimed
EP-1984319-A1 PROCESS FOR PREPARING AMINES BY CONDITIONING THE CATALYST WITH AMMONIA Evonik Degussa GmbH (DE) 2008-10-29 EP claimed
US-20060094699-A1 Combination therapy using an 11beta-hydroxysteroid dehydrogenase type 1 inhibitor and a glucocorticoid receptor agonist to minimize the side effects associated with glucocorticoid receptor agonist therapy HIGH POINT PHARMACEUTICALS, LLC 2006-05-04 US claimed
EP-1615666-A2 COMBINATION OF AN 11BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 INHIBITOR AND AN ANTIHYPERTENSIVE AGENT NOVO NORDISK A/S (DK) 2006-01-18 EP claimed
EP-1615667-A2 COMBINATIONS OF AN 11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 INHIBITOR AND A GLUCOCORTICOID RECEPTOR AGONIST NOVO NORDISK A/S (DK) 2006-01-18 EP claimed
EP-1615698-A2 NEW AMIDE DERIVATIVES AND PHARMACEUTICAL USE THEREOF NOVO NORDISK A/S (DK) 2006-01-18 EP claimed
WO-2004089416-A2 COMBINATION OF AN 11BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 INHIBITOR AND AN ANTIHYPERTENSIVE AGENT NOVO NORDISK A/S (DK) 2004-10-21 WO claimed
WO-2004089470-A2 NEW AMIDE DERIVATIVES AND PHARMACEUTICAL USE THEREOF NOVO NORDISK A/S (DK) 2004-10-21 WO claimed
WO-2004089415-A2 COMBINATIONS OF AN 11β-HYDROXYSTEROID DEHYDROGENASE TYPE 1 INHIBITOR AND A GLUCOCORTICOID RECEPTOR AGONIST NOVO NORDISK A/S (DK) 2004-10-21 WO claimed
US-4042642-A 1,3-BIS(MORPHOLINOTHIO)-IMIDAZOLIDINONE THE GOODYEAR TIRE & RUBBER COMPANY (US) 1977-08-16 US claimed
US-3996505-A Capacitor with liquid polybutene dielectric MCGRAW-EDISON COMPANY (US) 1976-12-07 US claimed
US-3960857-A Urea additives for sulfur vulcanizable polymers THE GOODYEAR TIRE & RUBBER COMPANY (US) 1976-06-01 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060094699-A1 Combination therapy using an 11beta-hydroxysteroid dehydrogenase type 1 inhibitor and a glucocorticoid receptor agonist to minimize the side effects associated with glucocorticoid receptor agonist therapy HSD11B1, HSD17B1, NR3C1 DPP4 2080/4885KDM4E 4690/4885RAD52 2288/4885
US-20090137574-A1 Combination Therapy Using an 11Beta-Hydroxysteroid Dehydrogenase Type 1 Inhibitor and an Antihypertensive Agent for the Treatment of Metabolic Syndrome and Related Diseases and Disorders HSD11B1, HSD11B2, HSD17B1 DPP4 454/4885KDM4E 4283/4885RAD52 3188/4885
US-20090048466-A1 PROCESS FOR PREPARING AMINES BY CONDITIONING THE CATALYST WITH AMMONIA PNMT, HNMT, NAAA DPP4 4381/4885KDM4E 1228/4885RAD52 2894/4885
US-20090264412-A1 Combination Therapy Using An 11beta-Hydroxysteroid Dehydrogenase Type 1 Inhibitor And A Glucocorticoid Receptor Agonist To Minimize The Side Effects Associated With Glucocorticoid Receptor Agonist Therapy HSD11B1, HSD17B1, NR3C1 DPP4 2080/4885KDM4E 4690/4885RAD52 2288/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.