SCHEMBL31720801

SCHEMBL31720801

O=C(O)c1cccc(Cc2nc3c(Cc4ccccc4)[nH]c(-c4ccccc4)cn-3c2=O)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ACMSD Q8TDX5 4/20 0.41
▸ CDC7 O00311 1/20 0.38
▸ MRGPRX4 Q96LA9 1/20 0.38
▸ PLA2G2A P14555 1/20 0.38
▸ ADORA2B P29275 1/20 0.37
▸ MAPT P10636 1/20 0.37
▸ KMT2A Q03164 1/20 0.37
▸ NPC1 O15118 1/20 0.36
▸ RAB9A P51151 1/20 0.36
▸ SMN1; SMN2 Q16637 1/20 0.36
▸ CA1 P00915 1/20 0.36
▸ CA2 P00918 1/20 0.36
▸ CA9 Q16790 1/20 0.36
▸ HTT P42858 1/20 0.36
▸ PARP1 P09874 1/20 0.36
▸ DHFR P00374 1/20 0.36
▸ CASP3 P42574 1/20 0.36
▸ SENP8 Q96LD8 1/20 0.36
▸ SENP7 Q9BQF6 1/20 0.36
▸ SENP6 Q9GZR1 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19206734 1.00 ACMSD (0.41) ACMSDCDC7MRGPRX4PLA2G2AADORA2B
SCHEMBL19206697 0.91 MAPT (0.39) ACMSDCDC7MAPTKMT2ANPC1
SCHEMBL19206672 0.89 CDC7 (0.38) CDC7MAPTHTT
SCHEMBL492636 0.88 LTB4R (0.41) CDC7MAPTRAB9ASMN1; SMN2CA1
SCHEMBL19206714 0.88 ALDH1A1 (0.38) CDC7MAPTKMT2APARP1
SCHEMBL20211740 0.87 KEAP1 (0.39) ACMSDPLA2G2AADORA2BMAPTKMT2A
SCHEMBL30800214 0.87 KEAP1 (0.39) ACMSDPLA2G2AADORA2BMAPTKMT2A
SCHEMBL19206676 0.87 LTB4R (0.38) CDC7MAPTCA1CA2CA9
SCHEMBL20543423 0.86 PDE3B (0.38) CDC7ADORA2BMAPTNPC1RAB9A
SCHEMBL20543611 0.86 THRB (0.42) CDC7MAPTKMT2ANPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250340923-A1 SUBSTITUTED IMIDAZO[1,2-a]PYRAZINES AS LUCIFERASE SUBSTRATES PROMEGA CORP (US) 2025-11-06 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250340923-A1 SUBSTITUTED IMIDAZO[1,2-a]PYRAZINES AS LUCIFERASE SUBSTRATES PGLS, AADAC, GLB1 ACMSD 665/4885CDC7 1805/4885MRGPRX4 3256/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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