Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.59 |
| ▸ | CA5A | P35218 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 3/20 | 0.39 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | CA7 | P43166 | 3/20 | 0.39 |
| ▸ | CA9 | Q16790 | 3/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28721957 | 0.79 | HSP90AB1 (0.58) | HSP90AB1CA5AACHELMNACYP3A4 | |
| SCHEMBL3192007 | 0.78 | SELP (0.42) | HSP90AB1CA5ALMNAHPGDPOLB | |
| SCHEMBL200141 | 0.78 | CTBP2 (0.56) | CA5ALMNACYP3A4KMT2ACA12 | |
| SCHEMBL477986 | 0.77 | CA2 (0.58) | HSP90AB1ACHELMNAMEN1KMT2A | |
| SCHEMBL8936329 | 0.76 | HSP90AB1 (0.55) | HSP90AB1CA5AACHELMNACYP3A4 | |
| SCHEMBL27896449 | 0.76 | POLB (0.42) | HSP90AB1CA5AHPGDPOLB | |
| Phloroglucinol SCHEMBL28617918 | 0.76 | ALDH1A1 (0.59) | HSP90AB1CA5AACHELMNACYP3A4 | |
| SCHEMBL12081769 | 0.75 | RXRA (0.44) | HSP90AB1CYP3A4PTGS2MEN1KMT2A | |
| SCHEMBL10865907 | 0.75 | TPMT (0.42) | CYP3A4MEN1KMT2APOLB | |
| SCHEMBL13438518 | 0.75 | AKR1B1 (0.48) | LMNAMEN1KMT2AHPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200205541-A1 | METHOD FOR STRAIGHTENING KERATINOUS FIBERS USING HEATING MEANS AND AN AROMATIC COMPOUND | L'OREAL (FR) | 2020-07-02 | — | — | US | claimed |
| US-20130298933-A1 | METHOD FOR STRAIGHTENING KERATINOUS FIBERS USING HEATING MEANS AND AN AROMATIC COMPOUND | L'OREAL (FR) | 2013-11-14 | — | — | US | claimed |
| US-20100300472-A1 | METHOD FOR STRAIGHTENING KERATINOUS FIBERS USING HEATING MEANS AND AN AROMATIC COMPOUND | L'OREAL S.A. (FR) | 2010-12-02 | — | — | US | claimed |
| EP-4554549-A1 | COMPOSITION COMPRISING SKIN CARE ACTIVE INGREDIENT OR CELLULOSE COMPOUND | L'OREAL (FR) | 2025-05-21 | — | — | EP | disclosed |
| CN-119677492-A | Composition comprising a skin care active or a cellulose compound | 莱雅公司 | 2025-03-21 | — | — | CN | disclosed |
| US-20250064703-A1 | COMPOSITION COMPRISING SOLUBILIZED POLYPHENOL | OREAL (FR) | 2025-02-27 | — | — | US | disclosed |
| EP-4452205-A1 | COMPOSITION COMPRISING SOLUBILIZED POLYPHENOL | L'OREAL (FR) | 2024-10-30 | — | — | EP | disclosed |
| CN-118542820-A | Topical delivery system for active ingredients | 莱雅公司 | 2024-08-27 | — | — | CN | disclosed |
| CN-118414140-A | Compositions comprising dissolved polyphenols | 莱雅公司 | 2024-07-30 | — | — | CN | disclosed |
| EP-4337159-A1 | COMPOSITION COMPRISING SKIN CARE ACTIVE INGREDIENT AND TWO POLYGLYCERYL FATTY ACID ESTERS | L'OREAL (FR) | 2024-03-20 | — | — | EP | disclosed |
| WO-2024014310-A1 | COMPOSITION COMPRISING SKIN CARE ACTIVE INGREDIENT OR CELLULOSE COMPOUND | L'OREAL (FR) | 2024-01-18 | — | — | WO | disclosed |
| EP-3171853-A1 | COMPOSITION IN THE FORM OF NANO OR MICRO EMULSION OR WITH LAMELLAR STRUCTURE | L'Oréal (FR) | 2017-05-31 | — | — | EP | disclosed |
| US-20170087064-A1 | COMPOSITION IN THE FORM OF NANO OR MICRO EMULSION OR WITH LAMELLAR STRUCTURE | L'OREAL (FR) | 2017-03-30 | — | — | US | disclosed |
| WO-2015198922-A1 | COMPOSITION IN THE FORM OF NANO OR MICRO EMULSION OR WITH LAMELLAR STRUCTURE | L'OREAL (FR) | 2015-12-30 | — | — | WO | disclosed |
| US-20140326268-A1 | PROCESS FOR STRAIGHTENING KERATIN FIBRES WITH A HEATING MEANS AND DENATURING AGENTS | L'OREAL (FR) | 2014-11-06 | — | — | US | disclosed |
| US-8765107-B2 | Process for straightening keratin fibres with a heating means and denaturing agents | L'OREAL (FR) | 2014-07-01 | — | — | US | disclosed |
| US-20130298933-A1 | METHOD FOR STRAIGHTENING KERATINOUS FIBERS USING HEATING MEANS AND AN AROMATIC COMPOUND | L'OREAL (FR) | 2013-11-14 | — | — | US | disclosed |
| US-20120192888-A1 | PROCESS FOR STRAIGHTENING KERATIN FIBRES WITH A HEATING MEANS AND DENATURING AGENTS | L 'Oréal S.A., (FR) | 2012-08-02 | — | — | US | disclosed |
| US-20100300472-A1 | METHOD FOR STRAIGHTENING KERATINOUS FIBERS USING HEATING MEANS AND AN AROMATIC COMPOUND | L'OREAL S.A. (FR) | 2010-12-02 | — | — | US | disclosed |
| US-20100028280-A1 | PROCESS FOR STRAIGHTENING KERATIN FIBRES WITH A HEATING MEANS AND DENATURING AGENTS | L'OREAL S.A. (FR) | 2010-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120192888-A1 | PROCESS FOR STRAIGHTENING KERATIN FIBRES WITH A HEATING MEANS AND DENATURING AGENTS | KRT18, KRTCAP2, TUBB4A | HSP90AB1 60/4885CA5A 1915/4885ACHE 2379/4885 |
| US-20200205541-A1 | METHOD FOR STRAIGHTENING KERATINOUS FIBERS USING HEATING MEANS AND AN AROMATIC COMPOUND | KRT18, TUBB4A, TUBB4B | HSP90AB1 405/4885CA5A 450/4885ACHE 4025/4885 |
| US-20100028280-A1 | PROCESS FOR STRAIGHTENING KERATIN FIBRES WITH A HEATING MEANS AND DENATURING AGENTS | KRT18, KRTCAP2, TUBB4A | HSP90AB1 60/4885CA5A 1915/4885ACHE 2379/4885 |
| US-20250064703-A1 | COMPOSITION COMPRISING SOLUBILIZED POLYPHENOL | PROC, GANC, LGALS1 | HSP90AB1 1012/4885CA5A 2011/4885ACHE 2711/4885 |
| US-20170087064-A1 | COMPOSITION IN THE FORM OF NANO OR MICRO EMULSION OR WITH LAMELLAR STRUCTURE | LRAT, LIPA, DAGLA | HSP90AB1 2699/4885CA5A 3443/4885ACHE 2486/4885 |
| US-20100300472-A1 | METHOD FOR STRAIGHTENING KERATINOUS FIBERS USING HEATING MEANS AND AN AROMATIC COMPOUND | KRT18, TUBB4A, TUBB4B | HSP90AB1 405/4885CA5A 450/4885ACHE 4025/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.