Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3186534 | 0.97 | LMNA (0.34) | LMNA | |
| Iodide SCHEMBL20875135 | 0.94 | LMNA (0.33) | LMNA | |
| Bromide SCHEMBL20912803 | 0.94 | LMNA (0.33) | LMNA | |
| Water SCHEMBL26669930 | 0.81 | LMNA (0.44) | LMNA | |
| SCHEMBL10078318 | 0.78 | LMNA (0.46) | LMNA | |
| SCHEMBL6061606 | 0.76 | LMNA (0.32) | LMNA | |
| Ammonia Solution, Strong SCHEMBL28815192 | 0.76 | LMNA (0.44) | LMNA | |
| SCHEMBL8465991 | 0.76 | LMNA (0.36) | LMNA | |
| SCHEMBL30149933 | 0.75 | ALDH1A1 (0.31) | LMNA | |
| SCHEMBL10078986 | 0.74 | LMNA (0.42) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3470372-B1 | METAL-CONTAINING CHA-TYPE ZEOLITE AND METHOD FOR PRODUCING THE SAME | TOSOH CORP (JP) | 2021-06-30 | — | — | EP | disclosed |
| US-10953390-B2 | CHA-type zeolite and method for producing the same | TOSOH CORPORATION (JP) | 2021-03-23 | — | — | US | disclosed |
| US-10821426-B2 | Metal-containing cha-type zeolite and method for producing the same | TOSOH CORPORATION (JP) | 2020-11-03 | — | — | US | disclosed |
| US-20190143309-A1 | CHA-TYPE ZEOLITE AND METHOD FOR PRODUCING THE SAME | TOSOH CORPORATION (JP) | 2019-05-16 | — | — | US | disclosed |
| EP-3473598-A1 | CHA-TYPE ZEOLITE AND PRODUCTION METHOD THEREFOR | Tosoh Corporation (JP) | 2019-04-24 | — | — | EP | disclosed |
| EP-3470372-A1 | METAL-CONTAINING CHA-TYPE ZEOLITE AND METHOD FOR PRODUCING THE SAME | Tosoh Corporation (JP) | 2019-04-17 | — | — | EP | disclosed |
| US-20190105639-A1 | METAL-CONTAINING CHA-TYPE ZEOLITE AND METHOD FOR PRODUCING THE SAME | TOSOH CORPORATION (JP) | 2019-04-11 | — | — | US | disclosed |
| US-7754187-B2 | Synthesis of chabazite-containing molecular sieves and their use in the conversion of oxygenates to olefins | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2010-07-13 | — | — | US | disclosed |
| US-7670589-B2 | Synthesis of chabazite-containing molecular sieves and their use in the conversion of oxygenates to olefins | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2010-03-02 | — | — | US | disclosed |
| US-20080045767-A1 | Synthesis of chabazite-containing molecular sieves and their use in the conversion of oxygenates to olefins | EXXONMOBIL CHEMICAL PATENTS INC. | 2008-02-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080045767-A1 | Synthesis of chabazite-containing molecular sieves and their use in the conversion of oxygenates to olefins | POF1B, CHAF1B, HAO2 | LMNA 3844/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.