Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PADI1 | Q9ULC6 | 5/20 | 0.55 |
| ▸ | PADI4 | Q9UM07 | 5/20 | 0.55 |
| ▸ | PADI2 | Q9Y2J8 | 4/20 | 0.55 |
| ▸ | PDE4A | P27815 | 3/20 | 0.55 |
| ▸ | PADI3 | Q9ULW8 | 3/20 | 0.55 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.55 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.55 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.55 |
| ▸ | PADI6 | Q6TGC4 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 3/20 | 0.54 |
| ▸ | CA1 | P00915 | 2/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | HPGDS | O60760 | 5/20 | 0.51 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.49 |
| ▸ | MMP12 | P39900 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5569820 | 1.00 | PADI1 (0.55) | PADI1PADI4PADI2PDE4APADI3 | |
| SCHEMBL18803701 | 0.87 | CA2 (0.51) | CA2CA1CA12CA9ALDH1A1 | |
| SCHEMBL2791574 | 0.85 | CA2 (0.66) | CA2CA1CA12CA9SLC1A2 | |
| SCHEMBL2792747 | 0.85 | CA2 (0.66) | CA2CA1CA12CA9SLC1A2 | |
| SCHEMBL9943491 | 0.85 | CA2 (0.66) | CA2CA1CA12CA9SLC1A2 | |
| SCHEMBL24945573 | 0.84 | CTRB1 (0.55) | PADI1PADI4PADI2PDE4APADI3 | |
| SCHEMBL24945572 | 0.84 | CTRB1 (0.55) | PADI1PADI4PADI2PDE4APADI3 | |
| SCHEMBL20277616 | 0.83 | HPGDS (0.71) | CA2CA1CA12CA9HPGDS | |
| SCHEMBL17244326 | 0.83 | HPGDS (0.71) | CA2CA1CA12CA9HPGDS | |
| SCHEMBL4194914 | 0.81 | HPGDS (0.65) | PADI1PADI4PADI2PDE4APADI3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100113756-A1 | LUMINESCENT METAL COMPLEXES FOR MONITORING RENAL FUNCTION | MALLINCKRODT INC. (US) | 2010-05-06 | — | — | US | disclosed |
| US-7674902-B2 | Luminescent metal complexes for monitoring renal function | MALLINCKRODT INC. (US) | 2010-03-09 | — | — | US | disclosed |
| US-20080299038-A1 | Luminescent Metal Complexes for Monitoring Renal Function | MALLINCKRODT INC. (US) | 2008-12-04 | — | — | US | disclosed |
| EP-1793866-A1 | LUMINESCENT METAL COMPLEXES FOR MONITORING RENAL FUNCTION | MALLINCKRODT, INC. (US) | 2007-06-13 | — | — | EP | disclosed |
| WO-2006026038-A1 | LUMINESCENT METAL COMPLEXES FOR MONITORING RENAL FUNCTION | MALLINCKRODT INC. (US) | 2006-03-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080299038-A1 | Luminescent Metal Complexes for Monitoring Renal Function | REN, GLS, ATP6V1B1 | PADI1 1070/4885PADI4 1701/4885PADI2 1663/4885 |
| US-20100113756-A1 | LUMINESCENT METAL COMPLEXES FOR MONITORING RENAL FUNCTION | REN, GLS, ATP6V1B1 | PADI1 1140/4885PADI4 1687/4885PADI2 1698/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.