Linoleic Acid

Linoleic Acid

SCHEMBL320102

CCCCC/C=C\C/C=C\CCCCCCCC(=O)O.CCCCCC=CCC=CCCCCCCCC(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARG P37231 7/20 1.00
PPARD Q03181 6/20 1.00
PPARA Q07869 6/20 1.00
ALDH1A1 P00352 5/20 1.00
F7 P08709 5/20 1.00
F3 P13726 5/20 1.00
FABP4 P15090 4/20 1.00
HSD17B10 Q99714 4/20 1.00
FFAR1 O14842 3/20 1.00
PTGS1 P23219 3/20 1.00
LMNA P02545 3/20 1.00
CYP19A1 P11511 3/20 1.00
ALOX15 P16050 3/20 1.00
NR4A2 P43354 3/20 1.00
KDM4E B2RXH2 2/20 1.00
CYP3A4 P08684 2/20 1.00
HPGD P15428 2/20 1.00
AKR1C3 P42330 2/20 1.00
TDP1 Q9NUW8 2/20 1.00
DUSP3 P51452 2/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16685715 1.00 PPARG (1.00) PPARGPPARDPPARAALDH1A1F7
SCHEMBL15880317 1.00 PPARG (1.00) PPARGPPARDPPARAALDH1A1F7
Linoleic Acid SCHEMBL20856202 1.00 PPARG (1.00) PPARGPPARDPPARAALDH1A1F7
SCHEMBL22498259 1.00 PPARG (1.00) PPARGPPARDPPARAALDH1A1F7
SCHEMBL22498256 1.00 PPARG (1.00) PPARGPPARDPPARAALDH1A1F7
Arachidic Acid SCHEMBL20528087 1.00 PPARG (1.00) PPARGPPARDPPARAALDH1A1F7
Linoleic Acid SCHEMBL25294178 1.00 PPARG (1.00) PPARGPPARDPPARAALDH1A1F7
SCHEMBL22498258 1.00 PPARG (1.00) PPARGPPARDPPARAALDH1A1F7
Dihomo-Gamma-Linolenic Acid SCHEMBL20656585 1.00 PPARG (1.00) PPARGPPARDPPARAALDH1A1F7
SCHEMBL21411004 1.00 PPARG (1.00) PPARGPPARDPPARAALDH1A1F7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011080296-A1 CONTINUOUS PROCESS OF OXIDATIVE CLEAVAGE OF VEGETABLE OILS NOVAMONT S.P.A. (IT) 2011-07-07 WO claimed
WO-2011080297-A1 CONTINUOUS PROCESS FOR THE PRODUCTION OF DERIVATIVES OF SATURATED CARBOXYLIC ACIDS NOVAMONT S.P.A. (IT) 2011-07-07 WO claimed
CN-117357548-A Oligonucleotide composition and method for preparing same 美国杰龙生物医药公司 2024-01-09 CN disclosed
CN-111228288-B Oligonucleotide composition and method for preparing same 美国杰龙生物医药公司 2023-10-20 CN disclosed
US-20120034205-A1 PKC ACTIVATORS AND ANTICOAGULANT IN REGIMEN FOR TREATING STROKE WEST VIRGINIA UNIVERSITY 2012-02-09 US disclosed
US-20120027687-A1 FATTY ACID PROTEIN KINASE C ACTIVATORS AND ANTICOAGULANT FOR THE TREATMENT OF STROKE WEST VIRGINIA UNIVERSITY 2012-02-02 US disclosed
US-20120010303-A1 WAXES DERIVED FROM METATHESIZED NATURAL OILS AND AMINES AND METHODS OF MAKING WILMAR TRADING PTE LTD (SG) 2012-01-12 US disclosed
EP-2399885-A1 Device and method for solubilizing, separating, removing and reacting carboxylic acids in aqueous or organic solutions by means of micro- or nanoemulsification Dietz, Ulrich (DE) 2011-12-28 EP disclosed
US-8063101-B2 Carotenoid analogs and derivatives for the prevention of platelet aggregation CARDAX PHARMACEUTICALS, INC. (US) 2011-11-22 US disclosed
US-20110277661-A1 NATURAL OIL BASED MARKING COMPOSITIONS AND THEIR METHODS OF MAKING CARGILL, INCORPORATED 2011-11-17 US disclosed
US-20110280852-A1 NITRO FATTY ACIDS - NEUROPROTECTION AND/OR INHIBITION OF COGNITIVE DECLINE NITROMEGA CORP. (US) 2011-11-17 US disclosed
WO-2011041639-A2 HETEROATOM CONTAINING SUBSTITUTED FATTY ACIDS MILLER RAYMOND A (US) 2011-04-07 WO disclosed
US-20110082206-A1 HETEROATOM CONTAINING SUBSTITUTED FATTY ACIDS COMPLEXA, INC. 2011-04-07 US disclosed
EP-2280928-A2 VINYL SUBSTITUTED FATTY ACIDS Complexa Inc. (US) 2011-02-09 EP disclosed
WO-2011011265-A2 STABILIZED HERBICIDAL FORMULATIONS AND METHODS OF USE ARYSTA LIFESCIENCE NORTH AMERICA, LLC (US) 2011-01-27 WO disclosed
US-20110015074-A1 STABILIZED HERBICIDAL FORMULATIONS AND METHODS OF USE ARYSTA LIFESCIENCE NORTH AMERICA LLC 2011-01-20 US disclosed
CN-100393209-C Modified oligonucleotides for telomerase inhibition GERON CORP (US) 2008-06-11 CN disclosed
EP-1917007-A2 INHIBITORS OF ANOREXIC LIPID HYDROLYSIS FOR THE TREATMENT OF EATING DISORDERS Rheoscience A/S (DK) 2008-05-07 EP disclosed
WO-2007006319-A2 INHIBITORS OF ANOREXIC LIPID HYDROLYSIS FOR THE TREATMENT OF EATING DISORDERS RHEOSCIENCE A/S (DK) 2007-01-18 WO disclosed
CN-1849069-A Modified oligonucleotides for telomerase inhibition GERON CORP (US) 2006-10-18 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120034205-A1 PKC ACTIVATORS AND ANTICOAGULANT IN REGIMEN FOR TREATING STROKE PRKCZ, PRKCA, PRKCB PPARG 1826/4885PPARD 2309/4885PPARA 1542/4885
US-20110280852-A1 NITRO FATTY ACIDS - NEUROPROTECTION AND/OR INHIBITION OF COGNITIVE DECLINE NLN, SMN1; SMN2, CASP10 PPARG 88/4885PPARD 290/4885PPARA 142/4885
US-20110015074-A1 STABILIZED HERBICIDAL FORMULATIONS AND METHODS OF USE DDT, HPD, CBR3 PPARG 1577/4885PPARD 965/4885PPARA 1724/4885
US-20120010303-A1 WAXES DERIVED FROM METATHESIZED NATURAL OILS AND AMINES AND METHODS OF MAKING PNMT, SQLE, SRM PPARG 3205/4885PPARD 3751/4885PPARA 3010/4885
US-20120027687-A1 FATTY ACID PROTEIN KINASE C ACTIVATORS AND ANTICOAGULANT FOR THE TREATMENT OF STROKE PRKCA, FABP7, PRKCZ PPARG 366/4885PPARD 852/4885PPARA 225/4885
US-20110082206-A1 HETEROATOM CONTAINING SUBSTITUTED FATTY ACIDS FFAR2, FFAR1, FFAR4 PPARG 14/4885PPARD 39/4885PPARA 15/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.