Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.66 |
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.52 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | NSD2 | O96028 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27556866 | 0.80 | ALDH1A1 (0.54) | ALDH1A1MAPTL3MBTL1KMT2AMEN1 | |
| SCHEMBL6081531 | 0.80 | ALDH1A1 (0.77) | ALDH1A1MAPTL3MBTL1KMT2AMEN1 | |
| SCHEMBL2353093 | 0.80 | ALDH1A1 (0.62) | ALDH1A1MAPTL3MBTL1KMT2AMEN1 | |
| SCHEMBL15082846 | 0.70 | ALDH1A1 (0.85) | ALDH1A1MAPTL3MBTL1KMT2AMEN1 | |
| SCHEMBL10813242 | 0.70 | ALDH1A1 (0.51) | ALDH1A1MAPTL3MBTL1KMT2AMEN1 | |
| SCHEMBL10998010 | 0.70 | ALDH1A1 (0.85) | ALDH1A1MAPTL3MBTL1KMT2AMEN1 | |
| SCHEMBL10968040 | 0.70 | ALDH1A1 (0.51) | ALDH1A1MAPTL3MBTL1KMT2AMEN1 | |
| SCHEMBL17540297 | 0.70 | ALDH1A1 (0.64) | ALDH1A1MAPTL3MBTL1KMT2AMEN1 | |
| SCHEMBL2068814 | 0.69 | L3MBTL1 (0.60) | ALDH1A1MAPTL3MBTL1KMT2AMEN1 | |
| SCHEMBL12911265 | 0.69 | L3MBTL1 (0.60) | ALDH1A1MAPTL3MBTL1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100069684-A1 | ASSYMMETRIC HYDROGENERATION OF PROCHIRAL COMPOUNDS | DSM IP ASSETS B.V. (NL) | 2010-03-18 | — | — | US | disclosed |
| CN-100584460-C | Catalyst for asymmetric (transfer) hydrogenation | DSM IP ASSETS BV | 2010-01-27 | — | — | CN | disclosed |
| CN-1974010-A | Catalyst for asymmetric (transfer) hydrogenation | DSM IP ASSETS BV (NL) | 2007-06-06 | — | — | CN | disclosed |
| EP-1325013-B1 | CATALYST FOR ASYMMETRIC (TRANSFER) HYDROGENATION | DSM IP ASSETS BV (NL) | 2006-09-13 | — | — | EP | disclosed |
| CN-1827214-A | Catalyst for asymmetric (transfer) hydrogenation | DSM IP ASSETS BV (NL) | 2006-09-06 | — | — | CN | disclosed |
| EP-0901996-B1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE AMINES | MITSUI CHEMICALS INC (JP) | 2006-02-01 | — | — | EP | disclosed |
| US-6989461-B2 | Catalyst for asymmetric (transfer) hydrogenation | DSM IP ASSETS B.V. (NL) | 2006-01-24 | — | — | US | disclosed |
| US-20030199713-A1 | Catalyst for asymmetric (transfer) hydrogenation | JLL/DELTA DUTCH NEWCO B.V. (NL) | 2003-10-23 | — | — | US | disclosed |
| EP-1325013-A2 | CATALYST FOR ASYMMETRIC (TRANSFER) HYDROGENATION | DSM N.V. (NL) | 2003-07-09 | — | — | EP | disclosed |
| WO-2002004466-A2 | CATALYST FOR ASYMMETRIC (TRANSFER) HYDROGENATION | DSM N.V. (NL) | 2002-01-17 | — | — | WO | disclosed |
| US-6222072-B1 | RACTING IMINE WITH HYDRIDE REAGENT IN PRESENCE OF OPTICALLY ACTIVE METAL COMPOUND, WHEREIN HYDRIDE REAGENT IS A METAL HYDRIDE, REAGENT THAT UNDERGOES METAL EXCHANGE, METAL TRIALKOXY HYDRIDE COMPLEX OR METAL(TRICARBOXYLIC ACID)HYDRIDE | MITSUI CHEMICALS INC. (JP) | 2001-04-24 | — | — | US | disclosed |
| EP-0901996-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE AMINES | Mitsui Chemicals, Inc. (JP) | 1999-03-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100069684-A1 | ASSYMMETRIC HYDROGENERATION OF PROCHIRAL COMPOUNDS | PDHB, ME1, PDHA1 | ALDH1A1 102/4885MAPT 4861/4885L3MBTL1 2465/4885 |
| US-20030199713-A1 | Catalyst for asymmetric (transfer) hydrogenation | MLX, ACSL3, MSL1 | ALDH1A1 2008/4885MAPT 4501/4885L3MBTL1 295/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.