Sulfometuron

Sulfometuron

SCHEMBL3226563

COc1ccccc1C(=O)NS(=O)(=O)c1ccc(C(=O)NC2CC2)cc1.Cc1cc(C)nc(NC(=O)NS(=O)(=O)c2ccccc2C(=O)O)n1

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.50
ALDH1A1 P00352 2/20 0.42
RXFP1 Q9HBX9 2/20 0.41
GAA P10253 1/20 0.40
TSHR P16473 2/20 0.40
HPGD P15428 2/20 0.40
KCNA3 P22001 1/20 0.39
PPARG P37231 2/20 0.38
EPHX2 P34913 1/20 0.38
CYSLTR1 Q9Y271 1/20 0.38
MEN1 O00255 1/20 0.38
ABCC3 O15438 1/20 0.38
ABCC4 O15439 1/20 0.38
ABCC9 O60706 1/20 0.38
ABCB11 O95342 1/20 0.38
LMNA P02545 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2D6 P10635 1/20 0.38
MAPT P10636 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3218635 0.90 GAA (0.45) THRBALDH1A1RXFP1GAATSHR
Chlorsulfuron SCHEMBL3226526 0.82 ALDH1A1 (0.44) THRBALDH1A1GAATSHRPPARG
SCHEMBL3228011 0.82 GAA (0.43) THRBALDH1A1GAATSHRHPGD
SCHEMBL3226253 0.81 GAA (0.46) THRBALDH1A1RXFP1GAATSHR
SCHEMBL3232658 0.81 KCNA3 (0.37) THRBALDH1A1RXFP1GAAHPGD
SCHEMBL120129 0.81 KCNA3 (0.52) GAAHPGDKCNA3MEN1LMNA
SCHEMBL29687002 0.81 KCNA3 (0.52) GAAHPGDKCNA3MEN1LMNA
SCHEMBL3655826 0.81 KCNA3 (0.52) GAAHPGDKCNA3MEN1LMNA
SCHEMBL3225612 0.81 GAA (0.46) THRBALDH1A1RXFP1GAATSHR
Flupyrsulfuron SCHEMBL3220772 0.81 GAA (0.47) THRBALDH1A1GAATSHRKCNA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100234227-A1 MICROEMULSION CONCENTRATES BAYER CROPSCIENCE AG (DE) 2010-09-16 US disclosed
US-20100048516-A1 PENETRATION ENHANCER FOR FUNGICIDES BAYER CROPSCIENCE AG (DE) 2010-02-25 US disclosed
US-20080176746-A1 avoids antagonistically reduced activity or overdosage otherwise requiring split applications; by employing an oil suspension concentrate BAYER CROPSCIENCE AG (DE) 2008-07-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100048516-A1 PENETRATION ENHANCER FOR FUNGICIDES DDT, DCPS, TYMP THRB 1179/4885ALDH1A1 3150/4885RXFP1 3849/4885
US-20080176746-A1 avoids antagonistically reduced activity or overdosage otherwise requiring split applications; by employing an oil suspension concentrate LIPA, MGLL, ABHD6 THRB 2225/4885ALDH1A1 1862/4885RXFP1 4093/4885
US-20100234227-A1 MICROEMULSION CONCENTRATES ADH1C, MGLL, ADH1A THRB 2372/4885ALDH1A1 869/4885RXFP1 4425/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.