Chlorsulfuron

Chlorsulfuron

SCHEMBL3226526

COc1ccccc1C(=O)NS(=O)(=O)c1ccc(C(=O)NC2CC2)cc1.COc1nc(C)nc(NC(=O)NS(=O)(=O)c2ccccc2Cl)n1

nearest known ligand 0.63

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.44
KDM4E B2RXH2 1/20 0.44
NPC1 O15118 1/20 0.44
CYSLTR2 Q9NS75 3/20 0.41
CYSLTR1 Q9Y271 3/20 0.41
THRB P10828 1/20 0.39
FLT1 P17948 1/20 0.38
FLT4 P35916 1/20 0.38
KDR P35968 1/20 0.38
ABCC8 Q09428 2/20 0.38
MEN1 O00255 1/20 0.38
ABCC3 O15438 1/20 0.38
ABCC4 O15439 1/20 0.38
ABCC9 O60706 1/20 0.38
ABCB11 O95342 1/20 0.38
LMNA P02545 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2D6 P10635 1/20 0.38
MAPT P10636 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Logran SCHEMBL3228284 0.90 THRB (0.38) ALDH1A1KDM4ENPC1THRBABCC8
SCHEMBL3232658 0.87 KCNA3 (0.37) ALDH1A1KDM4ETHRBMEN1MAPT
Prosulfuron SCHEMBL3230152 0.87 TTK (0.37) ALDH1A1CYSLTR1THRBABCC8MEN1
SCHEMBL3220255 0.82 KDM4E (0.38) KDM4ETHRBGAA
Sulfometuron SCHEMBL3226563 0.82 THRB (0.50) ALDH1A1CYSLTR1THRBABCC8MEN1
SCHEMBL3218635 0.81 GAA (0.45) ALDH1A1CYSLTR2CYSLTR1THRBFLT1
Chlorsulfuron SCHEMBL54874 0.79 ALDH1A1 (0.61) ALDH1A1KDM4ENPC1MEN1MAPT
Chlorsulfuron SCHEMBL29636275 0.79 ALDH1A1 (0.61) ALDH1A1KDM4ENPC1MEN1MAPT
Chlorsulfuron SCHEMBL7902297 0.79 ALDH1A1 (0.61) ALDH1A1KDM4ENPC1MEN1MAPT
Chlorsulfuron SCHEMBL11325389 0.79 ALDH1A1 (0.61) ALDH1A1KDM4ENPC1MEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100234227-A1 MICROEMULSION CONCENTRATES BAYER CROPSCIENCE AG (DE) 2010-09-16 US disclosed
US-20100048516-A1 PENETRATION ENHANCER FOR FUNGICIDES BAYER CROPSCIENCE AG (DE) 2010-02-25 US disclosed
US-20080176746-A1 avoids antagonistically reduced activity or overdosage otherwise requiring split applications; by employing an oil suspension concentrate BAYER CROPSCIENCE AG (DE) 2008-07-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100048516-A1 PENETRATION ENHANCER FOR FUNGICIDES DDT, DCPS, TYMP ALDH1A1 3150/4885KDM4E 869/4885NPC1 2281/4885
US-20080176746-A1 avoids antagonistically reduced activity or overdosage otherwise requiring split applications; by employing an oil suspension concentrate LIPA, MGLL, ABHD6 ALDH1A1 1862/4885KDM4E 3886/4885NPC1 1170/4885
US-20100234227-A1 MICROEMULSION CONCENTRATES ADH1C, MGLL, ADH1A ALDH1A1 869/4885KDM4E 3160/4885NPC1 1267/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.