Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.49 |
| ▸ | TPSD1 | Q9BZJ3 | 2/20 | 0.49 |
| ▸ | TPSG1 | Q9NRR2 | 2/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 2/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | THPO | P40225 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3233223 | 0.79 | BCHE (0.65) | BCHECHRM3 | |
| SCHEMBL3228315 | 0.74 | CHRM3 (0.81) | CHRM3 | |
| SCHEMBL5709472 | 0.74 | HTR2A (0.50) | SIGMAR1HTR2ALMNACHRM3 | |
| SCHEMBL2408335 | 0.72 | SIGMAR1 (0.61) | OPRD1SIGMAR1HTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL10969939 | 0.70 | HTR2A (0.54) | OPRD1SIGMAR1HTR2ALMNATP53 | |
| SCHEMBL7276778 | 0.69 | SIGMAR1 (0.54) | OPRD1SIGMAR1HTR2ALMNAHDAC1 | |
| SCHEMBL23649597 | 0.67 | OPRM1 (0.85) | OPRD1SIGMAR1CHRM3TP53CYP1A2 | |
| SCHEMBL27633054 | 0.66 | ACHE (0.52) | OPRD1SIGMAR1HTR2ALMNA | |
| SCHEMBL7422609 | 0.66 | TPSAB1 (0.83) | TPSAB1TPSD1TPSG1 | |
| SCHEMBL7415237 | 0.66 | TPSAB1 (1.00) | TPSAB1TPSD1TPSG1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010007561-A1 | NOVEL COMPOUNDS ACTIVE AS MUSCARINIC RECEPTOR ANTAGONISTS | PFIZER LIMITED (GB) | 2010-01-21 | — | — | WO | disclosed |