Sugi Predict

Sugi Predict / Compounds / SCHEMBL323522

SCHEMBL323522

SCHEMBL323522

CCS(=O)(=O)N1CCNCC1

nearest known ligand 0.50

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 4/20 0.50
▸ KMT2A Q03164 2/20 0.49
▸ POLB P06746 2/20 0.39
▸ MAPT P10636 2/20 0.39
▸ NPSR1 Q6W5P4 1/20 0.39
▸ L3MBTL1 Q9Y468 1/20 0.39
▸ ALDH1A1 P00352 4/20 0.39
▸ HSD17B10 Q99714 1/20 0.36
▸ USP2 O75604 1/20 0.36
▸ TSHR P16473 1/20 0.35
▸ MAPK1 P28482 1/20 0.35
▸ ALOX15 P16050 1/20 0.35
▸ PKM P14618 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL894516 1.00 KDM4E (0.50) KDM4EKMT2APOLBMAPTNPSR1
Hydrochloric Acid SCHEMBL999646 0.97 KDM4E (0.48) KDM4EKMT2APOLBMAPTNPSR1
Hydrochloric Acid SCHEMBL2590541 0.89 KDM4E (0.52) KDM4EKMT2APOLBMAPTNPSR1
SCHEMBL190917 0.86 L3MBTL1 (0.45) KDM4EKMT2AMAPTL3MBTL1ALDH1A1
SCHEMBL31711454 0.84 L3MBTL1 (0.44) KDM4EKMT2AMAPTL3MBTL1ALDH1A1
Hydrochloric Acid SCHEMBL999877 0.84 L3MBTL1 (0.44) KDM4EKMT2AMAPTL3MBTL1ALDH1A1
SCHEMBL4073047 0.83 KMT2A (0.41) KDM4EKMT2AMAPTL3MBTL1ALDH1A1
Pyridine SCHEMBL28140811 0.82 KMT2A (0.49) KDM4EKMT2AMAPTNPSR1ALDH1A1
SCHEMBL962030 0.81 KMT2A (0.44) KDM4EKMT2APOLBMAPTALDH1A1
SCHEMBL3107942 0.81 GNAI3 (0.41) KDM4EKMT2AMAPTL3MBTL1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 462 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104046246-B The chemical-mechanical planarization of tungsten-containing substrate 气体产品与化学公司 2016-06-15 — — CN claimed
US-20140273458-A1 Chemical Mechanical Planarization for Tungsten-Containing Substrates AIR PRODUCTS AND CHEMICALS, INC. (US) 2014-09-18 — — US claimed
EP-2779217-A2 Chemical mechanical planarization for tungsten-containing substrates AIR PRODUCTS AND CHEMICALS, INC. (US) 2014-09-17 — — EP claimed
CN-104046246-A Chemical Mechanical Planarization for Tungsten-Containing Substrates AIR PROD & CHEM 2014-09-17 — — CN claimed
EP-1220856-B1 PYRAZOLO[4,3-D]PYRIMIDINE DERIVATIVES PFIZER LTD (GB) 2004-12-08 — — EP claimed
US-20040152712-A1 Pharmaceutically active compounds PFIZER INC. 2004-08-05 — — US claimed
US-20260132111-A1 Host-Targeted Pan-Respiratory Antiviral Small Molecule Therapeutics PROSETTA BIOSCIENCES INC (US) 2026-05-14 — — US disclosed
US-12459901-B2 Host-targeted pan-respiratory antiviral small molecule therapeutics PROSETTA BIOSCIENCES, INC. (US) 2025-11-04 — — US disclosed
WO-2025215579-A1 NOVEL NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS PFIZER INC. (US) 2025-10-16 — — WO disclosed
US-20250320213-A1 Nitrogen-Containing Heterocyclic Compounds PFIZER INC. (US) 2025-10-16 — — US disclosed
US-20250195488-A1 MEDICINE CONTAINING VITAMIN D DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT OR SOLVATE THEREOF, USED IN COMBINATION WITH IMMUNOMODULATORY SUBSTANCE TEIJIN PHARMA LIMITED (JP) 2025-06-19 — — US disclosed
CN-113164495-B Covalent targeting of E3 ligases 加利福尼亚大学董事会 2025-04-22 — — CN disclosed
US-20250120982-A1 COVALENT TARGETING OF E3 LIGASES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2025-04-17 — — US disclosed
EP-1421074-A1 NOVEL COMPOUNDS AstraZeneca AB (SE) 2004-05-26 — — EP disclosed
US-20040029898-A1 Substituted quinolines as antitumor agents ASTRAZENECA AB (SE) 2004-02-12 — — US disclosed
EP-1337524-A1 SUBSTITUTED QUINOLINES AS ANTITUMOR AGENTS AstraZeneca AB (SE) 2003-08-27 — — EP disclosed
WO-2003010158-A1 NOVEL COMPOUNDS ASTRAZENECA AB (SE) 2003-02-06 — — WO disclosed
WO-2002044166-A1 SUBSTITUTED QUINOLINES AS ANTITUMOR AGENTS ASTRAZENECA AB (SE) 2002-06-06 — — WO disclosed
EP-0439556-A4 HETEROCYCLIC PEPTIDE RENIN INHIBITORS — 1991-10-30 — — EP disclosed
US-4659708-A Anti-leishmanial lepidine derivatives THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) 1987-04-21 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040029898-A1 Substituted quinolines as antitumor agents NQO2, NQO1, TP53 KDM4E 1556/4885KMT2A 1585/4885POLB 2116/4885
US-20250195488-A1 MEDICINE CONTAINING VITAMIN D DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT OR SOLVATE THEREOF, USED IN COMBINATION WITH IMMUNOMODULATORY SUBSTANCE VDR, CYP24A1, AQP4 KDM4E 1262/4885KMT2A 3063/4885POLB 4341/4885
US-20260132111-A1 Host-Targeted Pan-Respiratory Antiviral Small Molecule Therapeutics NCOR1, HAVCR2, NR3C1 KDM4E 4577/4885KMT2A 4124/4885POLB 473/4885
US-20040152712-A1 Pharmaceutically active compounds PDE5A, PDE3A, PDE2A KDM4E 1524/4885KMT2A 4526/4885POLB 931/4885
US-20250320213-A1 Nitrogen-Containing Heterocyclic Compounds HRH4, HNMT, NNT KDM4E 2169/4885KMT2A 989/4885POLB 3980/4885
US-12459901-B2 Host-targeted pan-respiratory antiviral small molecule therapeutics MAVS, SARS1, ZC3HAV1 KDM4E 4045/4885KMT2A 4108/4885POLB 324/4885
US-20250120982-A1 COVALENT TARGETING OF E3 LIGASES STUB1, XIAP, RBX1 KDM4E 1093/4885KMT2A 869/4885POLB 2389/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.