SCHEMBL3256590

SCHEMBL3256590

CCCCCC(N)CC(N)C(=O)O

nearest known ligand 0.70

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
GRIK1 P39086 5/20 0.70
GRIK2 Q13002 4/20 0.70
SLC1A2 P43004 4/20 0.70
SLC1A1 P43005 4/20 0.70
SLC1A3 P43003 3/20 0.61
GPR84 Q9NQS5 3/20 0.48
FFAR1 O14842 1/20 0.48
SLC7A5 Q01650 1/20 0.48
ALDH1A1 P00352 1/20 0.47
MAPT P10636 1/20 0.47
LCK P06239 1/20 0.47
PPARD Q03181 1/20 0.47
ZDHHC20 Q5W0Z9 1/20 0.47
ZDHHC2 Q9UIJ5 1/20 0.47
S1PR2 O95136 4/20 0.46
S1PR1 P21453 4/20 0.46
S1PR3 Q99500 4/20 0.46
S1PR4 O95977 3/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26134019 0.98 GRIK1 (0.71) GRIK1GRIK2SLC1A2SLC1A1SLC1A3
SCHEMBL28762252 0.98 GRIK1 (0.71) GRIK1GRIK2SLC1A2SLC1A1SLC1A3
SCHEMBL5286582 0.85 SLC1A2 (0.67) GRIK1GRIK2SLC1A2SLC1A1SLC1A3
SCHEMBL9490505 0.84 GRIK1 (0.59) GRIK1GRIK2SLC1A2SLC1A1SLC1A3
SCHEMBL2730539 0.83 GRIK1 (0.68) GRIK1GRIK2SLC1A2SLC1A1SLC1A3
SCHEMBL5967305 0.83 GRIK1 (0.68) GRIK1GRIK2SLC1A2SLC1A1SLC1A3
SCHEMBL38735 0.83 GRIK1 (0.68) GRIK1GRIK2SLC1A2SLC1A1SLC1A3
SCHEMBL28900378 0.82 SLC1A2 (0.68) GRIK1GRIK2SLC1A2SLC1A1SLC1A3
SCHEMBL29924037 0.82 SLC1A2 (0.68) GRIK1GRIK2SLC1A2SLC1A1SLC1A3
SCHEMBL20838575 0.82 SLC1A2 (1.00) GRIK1GRIK2SLC1A2SLC1A1SLC1A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3238697-B1 CLEANING AGENT COMPOSITION CONTAINING ACYL BASIC AMINO ACID DERIVATIVE AJINOMOTO KK (JP) 2021-02-24 EP disclosed
EP-3238698-B1 COSMETIC COMPOSITION CONTAINING WATER-SOLUBLE MOISTURIZING COMPONENT AND ACYL BASIC AMINO ACID DERIVATIVE AJINOMOTO KK (JP) 2020-08-05 EP disclosed
EP-3176150-B1 MEDIUM-CHAIN ACYL BASIC AMINO ACID DERIVATIVE AJINOMOTO KK (JP) 2020-06-03 EP disclosed
US-10603262-B2 Cosmetic composition for use on hair and containing an acyl basic amino acid derivative AJINOMOTO CO., INC. (JP) 2020-03-31 US disclosed
EP-3238699-B1 COSMETIC COMPOSITION CONTAINING ACYL BASIC AMINO ACID DERIVATIVE AND ANIONIC WATER-SOLUBLE POLYMER AJINOMOTO KK (JP) 2020-03-25 EP disclosed
EP-3238701-B1 COSMETIC COMPOSITION FOR USE ON HAIR AND CONTAINING AN ACYL BASIC AMINO ACID DERIVATIVE AJINOMOTO KK (JP) 2020-02-19 EP disclosed
EP-3238700-B1 COSMETIC COMPOSITION CONTAINING ACYL BASIC AMINO ACID DERIVATIVE AND INORGANIC POWDER AJINOMOTO KK (JP) 2020-02-19 EP disclosed
US-10441520-B2 Cleaning agent composition containing acyl basic amino acid derivative AJINOMOTO CO., INC. (JP) 2019-10-15 US disclosed
EP-3238700-A1 COSMETIC COMPOSITION CONTAINING ACYL BASIC AMINO ACID DERIVATIVE AND INORGANIC POWDER AJINOMOTO CO., INC. (JP) 2017-11-01 EP disclosed
EP-3238699-A1 COSMETIC COMPOSITION CONTAINING ACYL BASIC AMINO ACID DERIVATIVE AND ANIONIC WATER-SOLUBLE POLYMER AJINOMOTO CO., INC. (JP) 2017-11-01 EP disclosed
US-20170281510-A1 COSMETIC COMPOSITION CONTAINING WATER-SOLUBLE MOISTURIZING COMPONENT AND ACYL BASIC AMINO ACID DERIVATIVE AJINOMOTO CO., INC. (JP) 2017-10-05 US disclosed
US-20170281495-A1 COSMETIC COMPOSITION CONTAINING ACYL BASIC AMINO ACID DERIVATIVE AND INORGANIC POWDER AJINOMOTO CO., INC. (JP) 2017-10-05 US disclosed
EP-3176150-A1 MEDIUM-CHAIN ACYL BASIC AMINO ACID DERIVATIVE Ajinomoto Co., Inc. (JP) 2017-06-07 EP disclosed
US-20170137372-A1 MEDIUM-CHAIN ACYL BASIC AMINO ACID DERIVATIVE AJINOMOTO CO., INC. (JP) 2017-05-18 US disclosed
US-8603504-B2 Cosmetic powder AJINOMOTO CO., INC. (JP) 2013-12-10 US disclosed
EP-1473027-B1 Basic amino acid derivatives as gelling agents AJINOMOTO KK (JP) 2010-03-31 EP disclosed
US-20060233728-A1 Cosmetic powder AJINOMOTO CO. INC. (JP) 2006-10-19 US disclosed
US-6921747-B2 Basic amino acid derivatives AJINOMOTO CO., INC. (JP) 2005-07-26 US disclosed
US-20040248812-A1 Basic amino acid derivatives AJINOMOTO CO. INC (JP) 2004-12-09 US disclosed
EP-1473027-A1 Basic amino acid derivatives as gelation agents Ajinomoto Co., Inc. (JP) 2004-11-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170281510-A1 COSMETIC COMPOSITION CONTAINING WATER-SOLUBLE MOISTURIZING COMPONENT AND ACYL BASIC AMINO ACID DERIVATIVE CUTA, AADAT, ASS1 GRIK1 1980/4885GRIK2 2656/4885SLC1A2 71/4885
US-10441520-B2 Cleaning agent composition containing acyl basic amino acid derivative PHOSPHO1, ACMSD, ABHD16A GRIK1 361/4885GRIK2 624/4885SLC1A2 112/4885
US-20170281495-A1 COSMETIC COMPOSITION CONTAINING ACYL BASIC AMINO ACID DERIVATIVE AND INORGANIC POWDER AADAT, SLC7A1, CUTA GRIK1 612/4885GRIK2 1127/4885SLC1A2 8/4885
US-20060233728-A1 Cosmetic powder CUTA, AADAT, AAAS GRIK1 3228/4885GRIK2 3378/4885SLC1A2 59/4885
US-20170137372-A1 MEDIUM-CHAIN ACYL BASIC AMINO ACID DERIVATIVE BCAT2, BCAT1, CUTA GRIK1 1222/4885GRIK2 1652/4885SLC1A2 112/4885
US-20040248812-A1 Basic amino acid derivatives BCAT1, BCAT2, SLC7A1 GRIK1 215/4885GRIK2 572/4885SLC1A2 40/4885
US-10603262-B2 Cosmetic composition for use on hair and containing an acyl basic amino acid derivative CUTA, TRPA1, NACA GRIK1 662/4885GRIK2 704/4885SLC1A2 95/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.