Sugi Predict

Sugi Predict / Compounds / SCHEMBL3264604

SCHEMBL3264604

SCHEMBL3264604

Clc1ccc(-c2nsc(-c3ccco3)n2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CASP3 P42574 1/20 0.56
▸ MAPT P10636 5/20 0.48
▸ HSD17B10 Q99714 4/20 0.48
▸ NPC1 O15118 4/20 0.48
▸ ALDH1A1 P00352 3/20 0.48
▸ RAB9A P51151 3/20 0.48
▸ HPGD P15428 2/20 0.48
▸ SMN1; SMN2 Q16637 2/20 0.48
▸ KDM4E B2RXH2 2/20 0.48
▸ TP53 P04637 2/20 0.48
▸ CYP1A2 P05177 2/20 0.48
▸ CYP2C19 P33261 2/20 0.48
▸ PTGDR2 Q9Y5Y4 1/20 0.47
▸ USP2 O75604 2/20 0.43
▸ TSHR P16473 2/20 0.43
▸ ALOX15 P16050 1/20 0.43
▸ CYP19A1 P11511 2/20 0.42
▸ LMNA P02545 3/20 0.41
▸ ADORA2A P29274 3/20 0.41
▸ ADORA1 P30542 3/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15364087 0.88 CASP3 (0.52) CASP3MAPTHSD17B10NPC1ALDH1A1
SCHEMBL3266165 0.83 CYP19A1 (0.39) CASP3MAPTHSD17B10NPC1ALDH1A1
SCHEMBL3261757 0.80 ALOX15 (0.54) CASP3MAPTNPC1ALDH1A1RAB9A
SCHEMBL31120321 0.78 CYP19A1 (0.66) MAPTNPC1ALDH1A1RAB9ASMN1; SMN2
SCHEMBL4255751 0.78 ALOX15 (0.43) CASP3MAPTHSD17B10NPC1ALDH1A1
SCHEMBL3262950 0.78 ALOX15 (0.43) CASP3MAPTHSD17B10NPC1ALDH1A1
SCHEMBL3266862 0.77 ALDH1A1 (0.36) CASP3MAPTHSD17B10NPC1ALDH1A1
SCHEMBL1219378 0.75 SIRT1 (0.44) CASP3MAPTHSD17B10NPC1ALDH1A1
SCHEMBL15364410 0.74 ALOX15 (0.54) CASP3MAPTNPC1ALDH1A1RAB9A
SCHEMBL27984401 0.74 ACHE (0.50) CASP3MAPTHSD17B10NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190327967-A1 COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES MONSANTO TECHNOLOGY LLC (US) 2019-10-31 — — US claimed
EP-2786994-B1 COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES MONSANTO TECHNOLOGY LLC (US) 2017-11-22 — — EP claimed
US-20170152247-A1 COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES MONSANTO TECHNOLOGY LLC (US) 2017-06-01 — — US claimed
US-9125410-B2 Compositions and methods for controlling nematodes MONSANTO TECHNOLOGY LLC (US) 2015-09-08 — — US claimed
EP-2786994-A1 Compositions and methods for controlling nematodes Monsanto Technology LLC (US) 2014-10-08 — — EP claimed
US-10827753-B2 Compositions and methods for controlling nematodes MONSANTO TECHNOLOGY LLC (US) 2020-11-10 — — US disclosed
US-10827753-B2 Compositions and methods for controlling nematodes MONSANTO TECHNOLOGY LLC (US) 2020-11-10 — — US disclosed
US-20190343120-A1 COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES MONSANTO TECHNOLOGY LLC (US) 2019-11-14 — — US disclosed
US-20190343120-A1 COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES MONSANTO TECHNOLOGY LLC (US) 2019-11-14 — — US disclosed
US-20190327967-A1 COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES MONSANTO TECHNOLOGY LLC (US) 2019-10-31 — — US disclosed
US-20190327967-A1 COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES MONSANTO TECHNOLOGY LLC (US) 2019-10-31 — — US disclosed
US-10375958-B2 Compositions and methods for controlling nematodes MONSANTO TECHNOLOGY LLC (US) 2019-08-13 — — US disclosed
US-8435999-B2 Compositions and methods for controlling nematodes MONSANTO TECHNOLOGY LLC (US) 2013-05-07 — — US disclosed
US-8435999-B2 Compositions and methods for controlling nematodes MONSANTO TECHNOLOGY LLC (US) 2013-05-07 — — US disclosed
CN-101820761-A Compositions and methods for controlling nematodes DIVERGENCE INC 2010-09-01 — — CN disclosed
EP-2184989-A1 COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES Divergence, Inc. (US) 2010-05-19 — — EP disclosed
WO-2009023721-A1 COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES DIVERGENCE, INC. (US) 2009-02-19 — — WO disclosed
US-20090048311-A1 Compostions and Methods for Controlling Nematodes MONSANTO TECHNOLOGY LLC 2009-02-19 — — US disclosed
US-20090048311-A1 Compostions and Methods for Controlling Nematodes MONSANTO TECHNOLOGY LLC 2009-02-19 — — US disclosed
US-20090048311-A1 Compostions and Methods for Controlling Nematodes MONSANTO TECHNOLOGY LLC 2009-02-19 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170152247-A1 COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES NOP2, ATL3, CYCS CASP3 477/4885MAPT 2961/4885HSD17B10 2408/4885
US-10827753-B2 Compositions and methods for controlling nematodes NOP2, ATL3, CYCS CASP3 477/4885MAPT 2961/4885HSD17B10 2408/4885
US-20190343120-A1 COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES NOP2, ATL3, CYCS CASP3 477/4885MAPT 2961/4885HSD17B10 2408/4885
US-20090048311-A1 Compostions and Methods for Controlling Nematodes NOP2, MT-CO3, CLPX CASP3 634/4885MAPT 1040/4885HSD17B10 2509/4885
US-10375958-B2 Compositions and methods for controlling nematodes NOP2, ATL3, CYCS CASP3 477/4885MAPT 2961/4885HSD17B10 2408/4885
US-20190327967-A1 COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES NOP2, ATL3, CYCS CASP3 477/4885MAPT 2961/4885HSD17B10 2408/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.