Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 8/20 | 0.37 |
| ▸ | NPC1 | O15118 | 6/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | STAT1 | P42224 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | NAAA | Q02083 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30571590 | 0.81 | L3MBTL1 (0.36) | L3MBTL1SMN1; SMN2ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL31426390 | 0.71 | RAB9A (0.51) | L3MBTL1RAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL30571964 | 0.70 | KDM4E (0.39) | L3MBTL1ALDH1A1HSD17B10LMNAKDM4E | |
| SCHEMBL30097038 | 0.67 | L3MBTL1 (0.38) | L3MBTL1RAB9ANPC1SMN1; SMN2ACHE | |
| SCHEMBL7421172 | 0.65 | TP53 (0.49) | RAB9ANPC1SMN1; SMN2ALDH1A1CYP1A2 | |
| SCHEMBL30097053 | 0.65 | MAOA (0.36) | L3MBTL1RAB9AALDH1A1TSHRHSD17B10 | |
| SCHEMBL13387445 | 0.64 | FAAH (0.58) | RAB9ANPC1SMN1; SMN2TSHRLMNA | |
| SCHEMBL29970021 | 0.64 | SMN1; SMN2 (0.44) | L3MBTL1RAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL29523653 | 0.63 | PIM1 (0.39) | L3MBTL1ALDH1A1MAPTTSHRMAPK1 | |
| SCHEMBL9267385 | 0.63 | ACHE (0.47) | RAB9ANPC1SMN1; SMN2CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260062443-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ALEXION PHARMA INC (US) | 2026-03-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260062443-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | C9, SSB, C1S | L3MBTL1 904/4885RAB9A 317/4885NPC1 848/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.