SCHEMBL32688022

SCHEMBL32688022

CCOC(=O)c1c(-c2ccc(Cl)cc2)c(C#N)c(SCc2nnn[nH]2)[nH]c1=O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 8/20 0.52
▸ KMT2A Q03164 3/20 0.52
▸ LMNA P02545 2/20 0.52
▸ KDM4E B2RXH2 4/20 0.49
▸ HPGD P15428 3/20 0.49
▸ CSF1R P07333 1/20 0.42
▸ TP53 P04637 1/20 0.41
▸ MDM2 Q00987 1/20 0.41
▸ MEN1 O00255 2/20 0.41
▸ MAPT P10636 2/20 0.41
▸ RXFP1 Q9HBX9 2/20 0.41
▸ NPSR1 Q6W5P4 2/20 0.41
▸ HTT P42858 1/20 0.41
▸ RECQL P46063 1/20 0.40
▸ HIF1A Q16665 1/20 0.40
▸ L3MBTL1 Q9Y468 1/20 0.40
▸ FNTA P49354 1/20 0.40
▸ FNTB P49356 1/20 0.40
▸ PRKCZ Q05513 1/20 0.37
▸ ACMSD Q8TDX5 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL32688263 0.87 ACMSD (0.42) ALDH1A1KMT2ALMNAKDM4EHPGD
SCHEMBL32688365 0.87 ALDH1A1 (0.44) ALDH1A1KMT2ALMNAKDM4EHPGD
SCHEMBL32688362 0.87 HSD11B1 (0.39) ALDH1A1KMT2ALMNAKDM4EHPGD
SCHEMBL32688110 0.86 MAPT (0.38) ALDH1A1KMT2ALMNAKDM4EHPGD
SCHEMBL32688422 0.86 MAPT (0.38) ALDH1A1KMT2ALMNAKDM4EHPGD
SCHEMBL32688106 0.83 ALDH1A1 (0.38) ALDH1A1KMT2ALMNAKDM4EHPGD
SCHEMBL32688269 0.82 HSD11B1 (0.45) ALDH1A1KMT2ALMNAKDM4EHPGD
SCHEMBL32688001 0.82 CUL4A (0.49) ALDH1A1KMT2ALMNAKDM4EHPGD
SCHEMBL32688235 0.82 HSD11B1 (0.45) ALDH1A1KMT2ALMNAKDM4EMEN1
SCHEMBL32688127 0.81 MAPT (0.45) ALDH1A1KMT2AKDM4EHPGDTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260078105-A1 Novel Aminocarboxymuconate Semialdehyde Decarboxylase Inhibitors ORSOBIO INC (US) 2026-03-19 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260078105-A1 Novel Aminocarboxymuconate Semialdehyde Decarboxylase Inhibitors CPT1B, CBR1, MUSK ALDH1A1 290/4885KMT2A 3400/4885LMNA 2438/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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