Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | LDHA | P00338 | 7/20 | 0.37 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | LDHB | P07195 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32688263 | 0.89 | ACMSD (0.42) | MAPTHSD11B1KMT2AALDH1A1LMNA | |
| SCHEMBL32688362 | 0.88 | HSD11B1 (0.39) | MAPTHSD11B1KMT2AALDH1A1LMNA | |
| SCHEMBL32688127 | 0.88 | MAPT (0.45) | MAPTKMT2AALDH1A1LDHAHPGD | |
| SCHEMBL32688422 | 0.88 | MAPT (0.38) | MAPTHSD11B1KMT2AALDH1A1LMNA | |
| SCHEMBL32688022 | 0.86 | ALDH1A1 (0.52) | MAPTHSD11B1KMT2AALDH1A1LMNA | |
| SCHEMBL32688269 | 0.84 | HSD11B1 (0.45) | HSD11B1KMT2AALDH1A1LMNALDHA | |
| SCHEMBL32688001 | 0.83 | CUL4A (0.49) | MAPTHSD11B1KMT2AALDH1A1LMNA | |
| SCHEMBL32688235 | 0.83 | HSD11B1 (0.45) | HSD11B1KMT2AALDH1A1LMNALDHA | |
| SCHEMBL32688250 | 0.78 | HSD11B1 (0.41) | HSD11B1KMT2ALMNAACMSDPOLB | |
| SCHEMBL32688034 | 0.77 | PDE9A (0.43) | KMT2APOLBKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260078105-A1 | Novel Aminocarboxymuconate Semialdehyde Decarboxylase Inhibitors | ORSOBIO INC (US) | 2026-03-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260078105-A1 | Novel Aminocarboxymuconate Semialdehyde Decarboxylase Inhibitors | CPT1B, CBR1, MUSK | MAPT 4018/4885HSD11B1 61/4885KMT2A 3400/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.