SCHEMBL3272230

SCHEMBL3272230

O=C(Cl)c1cc(C(=O)Cl)ncn1

nearest known ligand 0.39

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KMO O15229 13/20 0.39
MMP13 P45452 3/20 0.38
LMNA P02545 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.34
P2RX7 Q99572 1/20 0.34
SIRT6 Q8N6T7 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL550087 0.85 KMO (0.39) KMOLMNASIRT6
SCHEMBL24713180 0.84 KMO (0.36) KMOMMP13L3MBTL1SIRT6
SCHEMBL22462518 0.83 MAPK1 (0.42) LMNAL3MBTL1
SCHEMBL18422608 0.79 CA2 (0.47) KMOP2RX7
SCHEMBL71141 0.74 KMO (0.59) KMO
SCHEMBL21173952 0.72 MMP13 (0.38) KMOMMP13L3MBTL1
SCHEMBL22832283 0.72 MMP13 (0.42) KMOMMP13LMNAL3MBTL1
Fluoride SCHEMBL21173953 0.72 KMO (0.57) KMO
SCHEMBL24027356 0.72 KMO (0.39) KMOMMP13LMNAL3MBTL1
SCHEMBL642254 0.72 LMNA (0.52) KMOMMP13LMNAL3MBTL1P2RX7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3512905-B1 METHOD FOR PRODUCING A POLYBENZAZOL POLYMER (P) BASF SE (DE) 2022-08-24 EP claimed
EP-3512905-A1 METHOD FOR PRODUCING A POLYBENZAZOL POLYMER (P) BASF SE (DE) 2019-07-24 EP claimed
CN-111836849-B Process for producing fibers, films and moldings of polybenzazole polymer (P) 巴斯夫欧洲公司 2023-04-07 CN disclosed
WO-2023287736-A1 NOVEL BIS-AMIDE CONTAINING COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) 2023-01-19 WO disclosed
WO-2023287736-A1 NOVEL BIS-AMIDE CONTAINING COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) 2023-01-19 WO disclosed
EP-3512905-B1 METHOD FOR PRODUCING A POLYBENZAZOL POLYMER (P) BASF SE (DE) 2022-08-24 EP disclosed
EP-3762447-A1 METHOD FOR PRODUCING FIBRES, FILMS AND MOULDED BODIES OF A POLYBENZAZOLE POLYMER (P) BASF SE (DE) 2021-01-13 EP disclosed
US-20200407508-A1 METHOD FOR PRODUCING FIBERS, FILMS AND MOLDINGS OF A POLYBENZAZOLE POLYMER (P) BASF SE (DE) 2020-12-31 US disclosed
CN-111836849-A Process for producing fibers, films and moldings of polybenzazole polymer (P) 巴斯夫欧洲公司 2020-10-27 CN disclosed
WO-2019170529-A1 METHOD FOR PRODUCING FIBRES, FILMS AND MOULDED BODIES OF A POLYBENZAZOLE POLYMER (P) BASF SE (DE) 2019-09-12 WO disclosed
EP-3512905-A1 METHOD FOR PRODUCING A POLYBENZAZOL POLYMER (P) BASF SE (DE) 2019-07-24 EP disclosed
EP-1368323-B1 PYRIMIDINE MATRIX METALLOPROTEINASE INHIBITORS WARNER LAMBERT CO (US) 2010-06-30 EP disclosed
US-6936616-B2 Pyrimidine matrix metalloproteinase inhibitors WARNER-LAMBERT COMPANY (US) 2005-08-30 US disclosed
EP-1368323-A1 PYRIMIDINE MATRIX METALLOPROTEINASE INHIBITORS Warner-Lambert Company LLC (US) 2003-12-10 EP disclosed
US-20020151555-A1 Pyrimidine matrix metalloproteinase inhibitors BARVIAN NICOLE CHANTEL (US) 2002-10-17 US disclosed
WO-2002064571-A1 PYRIMIDINE MATRIX METALLOPROTEINASE INHIBITORS WARNER-LAMBERT COMPANY LLC (US) 2002-08-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020151555-A1 Pyrimidine matrix metalloproteinase inhibitors MMP13, MMP3, MMP11 KMO 1752/4885MMP13 1/4885LMNA 2315/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.