Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV6 | Q9H1D0 | 5/20 | 0.76 |
| ▸ | ORAI1 | Q96D31 | 4/20 | 0.76 |
| ▸ | ORAI2 | Q96SN7 | 4/20 | 0.76 |
| ▸ | ORAI3 | Q9BRQ5 | 4/20 | 0.76 |
| ▸ | MGLL | Q99685 | 2/20 | 0.57 |
| ▸ | KIF11 | P52732 | 5/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.34 |
| ▸ | HTR3B | O95264 | 1/20 | 0.34 |
| ▸ | PLAU | P00749 | 1/20 | 0.34 |
| ▸ | HTR3A | P46098 | 1/20 | 0.34 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.34 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2406706 | 0.87 | TRPV6 (1.00) | TRPV6ORAI1ORAI2ORAI3MGLL | |
| SCHEMBL3275158 | 0.79 | TRPV6 (1.00) | TRPV6ORAI1ORAI2ORAI3MGLL | |
| SCHEMBL12270441 | 0.78 | TRPV6 (0.79) | TRPV6ORAI1ORAI2ORAI3MGLL | |
| SCHEMBL2406670 | 0.76 | TRPV6 (0.76) | TRPV6ORAI1ORAI2ORAI3MGLL | |
| SCHEMBL4124 | 0.75 | ALDH1A1 (0.50) | TRPV6ORAI1ORAI2ORAI3MGLL | |
| SCHEMBL4179 | 0.73 | MGLL (1.00) | TRPV6ORAI1ORAI2ORAI3MGLL | |
| SCHEMBL3274509 | 0.73 | TRPV6 (0.61) | TRPV6ORAI1ORAI2ORAI3MGLL | |
| SCHEMBL28818315 | 0.73 | ALDH1A1 (0.48) | TRPV6ORAI1ORAI2ORAI3MGLL | |
| SCHEMBL21777186 | 0.73 | ALDH1A1 (0.48) | TRPV6ORAI1ORAI2ORAI3MGLL | |
| SCHEMBL20774399 | 0.73 | ALDH1A1 (0.48) | TRPV6ORAI1ORAI2ORAI3MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1961756-B1 | NOVEL BISBORON COMPOUND | JAPAN SCIENCE & TECH AGENCY (JP) | 2016-04-27 | — | — | EP | claimed |
| US-20100087645-A1 | NOVEL BISBORON COMPOUND | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2010-04-08 | — | — | US | claimed |
| EP-1961756-A1 | NOVEL BISBORON COMPOUND | Japan Science and Technology Agency (JP) | 2008-08-27 | — | — | EP | claimed |
| EP-1961756-B1 | NOVEL BISBORON COMPOUND | JAPAN SCIENCE & TECH AGENCY (JP) | 2016-04-27 | — | — | EP | disclosed |
| US-20100087645-A1 | NOVEL BISBORON COMPOUND | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2010-04-08 | — | — | US | disclosed |
| EP-1961756-A1 | NOVEL BISBORON COMPOUND | Japan Science and Technology Agency (JP) | 2008-08-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100087645-A1 | NOVEL BISBORON COMPOUND | KCNMB4, CA2, NR0B2 | TRPV6 61/4885ORAI1 58/4885ORAI2 414/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.