Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV6 | Q9H1D0 | 6/20 | 0.54 |
| ▸ | ORAI1 | Q96D31 | 5/20 | 0.54 |
| ▸ | ORAI2 | Q96SN7 | 5/20 | 0.54 |
| ▸ | ORAI3 | Q9BRQ5 | 5/20 | 0.54 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2403555 | 0.82 | KCNA3 (0.58) | TRPV6ORAI1ORAI2ORAI3PCSK9 | |
| SCHEMBL2412463 | 0.79 | LMNA (0.58) | TRPV6ORAI1ORAI2ORAI3PCSK9 | |
| SCHEMBL6664482 | 0.78 | LTA4H (0.59) | TRPV6ORAI1ORAI2ORAI3PCSK9 | |
| SCHEMBL6059706 | 0.77 | CYP1A2 (0.66) | LMNACYP1A2PTGS1SLC6A2CYP2C19 | |
| SCHEMBL3274847 | 0.76 | RAB9A (0.33) | ALDH1A1 | |
| SCHEMBL933 | 0.76 | — | — | |
| SCHEMBL2412647 | 0.76 | TRPV6 (0.93) | TRPV6ORAI1ORAI2ORAI3PCSK9 | |
| SCHEMBL10269840 | 0.75 | CA1 (0.72) | TRPV6ORAI1ORAI2ORAI3PCSK9 | |
| Hydrochloric Acid SCHEMBL27692384 | 0.74 | KCNA3 (0.55) | LMNACYP2C19HDAC6ALDH1A1RECQL | |
| SCHEMBL4707838 | 0.73 | NQO1 (0.47) | CA1CA2CA7LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1961756-B1 | NOVEL BISBORON COMPOUND | JAPAN SCIENCE & TECH AGENCY (JP) | 2016-04-27 | — | — | EP | claimed |
| US-20100087645-A1 | NOVEL BISBORON COMPOUND | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2010-04-08 | — | — | US | claimed |
| EP-1961756-A1 | NOVEL BISBORON COMPOUND | Japan Science and Technology Agency (JP) | 2008-08-27 | — | — | EP | claimed |
| EP-1961756-B1 | NOVEL BISBORON COMPOUND | JAPAN SCIENCE & TECH AGENCY (JP) | 2016-04-27 | — | — | EP | disclosed |
| US-20100087645-A1 | NOVEL BISBORON COMPOUND | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2010-04-08 | — | — | US | disclosed |
| EP-1961756-A1 | NOVEL BISBORON COMPOUND | Japan Science and Technology Agency (JP) | 2008-08-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100087645-A1 | NOVEL BISBORON COMPOUND | KCNMB4, CA2, NR0B2 | TRPV6 61/4885ORAI1 58/4885ORAI2 414/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.