SCHEMBL3277040

SCHEMBL3277040

CCCCNC(=O)c1cc2c(cc1C(=O)NCCCC)C(c1ccccc1)(c1ccccc1)c1cc(C(=O)O)c(C(=O)O)cc1O2

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.50
HTT P42858 1/20 0.50
HPGD P15428 4/20 0.45
BCL2 P10415 1/20 0.44
MCL1 Q07820 1/20 0.44
ALOX15 P16050 3/20 0.43
SMN1; SMN2 Q16637 2/20 0.42
MAPT P10636 2/20 0.42
KMT2A Q03164 1/20 0.42
NAAA Q02083 2/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
RAB9A P51151 2/20 0.41
DRD2 P14416 1/20 0.41
DRD3 P35462 1/20 0.41
CYP2C9 P11712 1/20 0.41
LMNA P02545 1/20 0.41
ALDH1A1 P00352 1/20 0.40
CA12 O43570 1/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3272803 0.83 TSHR (0.39) TSHRHTTHPGDBCL2MCL1
SCHEMBL3274334 0.81 ALOX5 (0.41) TSHRHPGDALOX15SMN1; SMN2MAPT
SCHEMBL3273061 0.77 POLB (0.40) TSHRHTTHPGDSMN1; SMN2KMT2A
SCHEMBL3277451 0.76 RAB9A (0.45) HTTHPGDSMN1; SMN2MAPTKMT2A
SCHEMBL6273378 0.73 HTT (0.86) TSHRHTTHPGDBCL2MCL1
SCHEMBL3271333 0.70 ALOX5 (0.39) TSHRHPGDALOX15KMT2ACYP2C9
SCHEMBL2638660 0.70 NAAA (0.59) TSHRHTTHPGDALOX15SMN1; SMN2
SCHEMBL19210845 0.69 TSHR (1.00) TSHRHTTHPGDALOX15SMN1; SMN2
SCHEMBL8502651 0.69 TSHR (0.58) TSHRHTTHPGDBCL2MCL1
SCHEMBL14811748 0.69 TSHR (0.71) TSHRHTTHPGDBCL2MCL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11760738-B2 Anisotropic copoly(imide oxetane) coatings and articles of manufacture, copoly(imide oxetane)s containing pendant fluorocarbon moieties, oligomers and processes therefor United States of America as represented by the Adminstrator of NASA (US) 2023-09-19 US disclosed
US-20220017479-A1 ANISOTROPIC COPOLY(IMIDE OXETANE) COATINGS AND ARTICLES OF MANUFACTURE, COPOLY(IMIDE OXETANE)S CONTAINING PENDANT FLUOROCARBON MOIETIES, OLIGOMERS AND PROCESSES THEREFOR UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA 2022-01-20 US disclosed
US-11130742-B2 Anisotropic copoly(imide oxetane) coatings and articles of manufacture, copoly(imide oxetane)s containing pendant fluorocarbon moieties, oligomers and processes therefor UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (US) 2021-09-28 US disclosed
US-10808079-B2 Synthesis of copolyimides containing fluorine and silicon surface modifying agents UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (US) 2020-10-20 US disclosed
US-20200247770-A1 ANISOTROPIC COPOLY(IMIDE OXETANE) COATINGS AND ARTICLES OF MANUFACTURE, COPOLY(IMIDE OXETANE)S CONTAINING PENDANT FLUOROCARBON MOIETIES, OLIGOMERS AND PROCESSES THEREFOR UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA 2020-08-06 US disclosed
US-10626098-B2 Anisotropic copoly(imide oxetane) coatings and articles of manufacture, copoly (imide oxetane)s containing pendant fluorocarbon moieties, oligomers and processes therefor UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (US) 2020-04-21 US disclosed
US-20180118702-A1 ANISOTROPIC COPOLY(IMIDE OXETANE) COATINGS AND ARTICLES OF MANUFACTURE, COPOLY(IMIDE OXETANE)S CONTAINING PENDANT FLUOROCARBON MOIETIES, OLIGOMERS AND PROCESSES THEREFOR UNITES STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA 2018-05-03 US disclosed
US-9822088-B2 Anisotropic copoly(imide oxetane) coatings and articles of manufacture, copoly(imide oxetane)s containing pendant fluorocarbon moieties, oligomers and processes therefor THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (US) 2017-11-21 US disclosed
WO-2016160512-A1 SYNTHESIS OF COPOLYIMIDES CONTAINING FLUORINE AND SILICON SURFACE MODIFYING AGENTS USA, as represented by the Administrator of the National Aeronautics and Space Administration (US) 2016-10-06 WO disclosed
US-20160280858-A1 Synthesis of Copolyimides Containing Fluorine and Silicon Surface Modifying Agents NATIONAL INSTITUTE OF AEROSPACE 2016-09-29 US disclosed
US-7691471-B2 Polycyclic polyimides and compositions and methods relating thereto E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-04-06 US disclosed
US-20090263640-A1 POLYCYCLIC POLYIMIDES AND COMPOSITIONS AND METHODS RELATING THERETO E.I. DU PONT DE NEMOURS AND COMPANY (US) 2009-10-22 US disclosed
US-20090226642-A1 LOW COLOR POLYIMIDE COMPOSITIONS USEFUL IN OPTICAL TYPE APPLICATIONS AND METHODS AND COMPOSITIONS RELATING THERETO E. I. DU PONT DE NEMOURS AND COMPANY (US) 2009-09-10 US disclosed
US-7572878-B2 Showing improved thermal stability properties in conjunction with improved optical transparency making these polyimides useful in electronic device applications; replacement for quartz or glass in optical display devices or the like E. I. DU PONT DE NEMOURS AND COMPANY (US) 2009-08-11 US disclosed
US-7550194-B2 Low color polyimide compositions useful in optical type applications and methods and compositions relating thereto E. I. DU PONT DE NEMOURS AND COMPANY (US) 2009-06-23 US disclosed
EP-1764381-B1 Polycyclic polyimides and compositions and their corresponding polyamic acids DU PONT (US) 2008-06-18 EP disclosed
US-20080138537-A1 Low color polyimide compositions useful in optical type applications and methods and compositions relating thereto U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2008-06-12 US disclosed
US-20070066734-A1 Polycyclic polyimides and compositions and methods relating thereto U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2007-03-22 US disclosed
EP-1764381-A1 Polycyclic polyimides and compositions and their corresponding polyamic acids E.I.Du pont de nemours and company (US) 2007-03-21 EP disclosed
EP-1749850-A1 Low color polyimide compositions useful in optical type applications and methods and compositions related thereto E.I. DUPONT DE NEMOURS AND COMPANY (US) 2007-02-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180118702-A1 ANISOTROPIC COPOLY(IMIDE OXETANE) COATINGS AND ARTICLES OF MANUFACTURE, COPOLY(IMIDE OXETANE)S CONTAINING PENDANT FLUOROCARBON MOIETIES, OLIGOMERS AND PROCESSES THEREFOR MACF1, OR51E2, FOS TSHR 4605/4885HTT 2047/4885HPGD 2289/4885
US-11760738-B2 Anisotropic copoly(imide oxetane) coatings and articles of manufacture, copoly(imide oxetane)s containing pendant fluorocarbon moieties, oligomers and processes therefor MACF1, OR51E2, FOS TSHR 4605/4885HTT 2047/4885HPGD 2289/4885
US-20200247770-A1 ANISOTROPIC COPOLY(IMIDE OXETANE) COATINGS AND ARTICLES OF MANUFACTURE, COPOLY(IMIDE OXETANE)S CONTAINING PENDANT FLUOROCARBON MOIETIES, OLIGOMERS AND PROCESSES THEREFOR MACF1, OR51E2, FOS TSHR 4605/4885HTT 2047/4885HPGD 2289/4885
US-10626098-B2 Anisotropic copoly(imide oxetane) coatings and articles of manufacture, copoly (imide oxetane)s containing pendant fluorocarbon moieties, oligomers and processes therefor MACF1, OR51E2, FOS TSHR 4605/4885HTT 2047/4885HPGD 2289/4885
US-11130742-B2 Anisotropic copoly(imide oxetane) coatings and articles of manufacture, copoly(imide oxetane)s containing pendant fluorocarbon moieties, oligomers and processes therefor MACF1, OR51E2, FOS TSHR 4605/4885HTT 2047/4885HPGD 2289/4885
US-20220017479-A1 ANISOTROPIC COPOLY(IMIDE OXETANE) COATINGS AND ARTICLES OF MANUFACTURE, COPOLY(IMIDE OXETANE)S CONTAINING PENDANT FLUOROCARBON MOIETIES, OLIGOMERS AND PROCESSES THEREFOR MACF1, OR51E2, FOS TSHR 4605/4885HTT 2047/4885HPGD 2289/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.