SCHEMBL3277451

SCHEMBL3277451

Cc1ccc(NC(=O)c2cc3c(cc2C(=O)Nc2ccc(C)cc2)C(c2ccccc2)(c2ccccc2)c2cc(C(=O)O)c(C(=O)O)cc2O3)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 7/20 0.45
NPC1 O15118 6/20 0.45
SMN1; SMN2 Q16637 3/20 0.45
LMNA P02545 2/20 0.45
TP53 P04637 2/20 0.45
HTT P42858 2/20 0.45
NFKB1 P19838 1/20 0.45
NFKB2 Q00653 1/20 0.45
RELA Q04206 1/20 0.45
HSD17B10 Q99714 1/20 0.45
MAPT P10636 2/20 0.45
KMT2A Q03164 8/20 0.45
ATM Q13315 1/20 0.45
MEN1 O00255 5/20 0.44
POLB P06746 2/20 0.44
ALDH1A1 P00352 2/20 0.44
HPGD P15428 1/20 0.44
MAOB P27338 2/20 0.43
MAOA P21397 1/20 0.43
GAA P10253 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12804755 0.90 KMT2A (0.45) RAB9ANPC1SMN1; SMN2LMNATP53
SCHEMBL3274334 0.82 ALOX5 (0.41) SMN1; SMN2HSD17B10MAPTKMT2AMEN1
SCHEMBL10014681 0.76 RAB9A (0.58) RAB9ANPC1SMN1; SMN2LMNATP53
SCHEMBL3277040 0.76 TSHR (0.50) RAB9ANPC1SMN1; SMN2LMNAHTT
SCHEMBL10489953 0.72 ALDH1A1 (0.76) RAB9ANPC1SMN1; SMN2LMNATP53
SCHEMBL3276678 0.71 HPGD (0.47) RAB9ANPC1SMN1; SMN2LMNATP53
SCHEMBL9885133 0.71 RAB9A (0.51) RAB9ANPC1SMN1; SMN2LMNATP53
SCHEMBL3271333 0.71 ALOX5 (0.39) HSD17B10KMT2AMEN1POLBALDH1A1
SCHEMBL17122454 0.71 ALDH1A1 (0.58) RAB9ANPC1SMN1; SMN2LMNATP53
SCHEMBL5583049 0.70 ALDH1A1 (0.69) RAB9ANPC1SMN1; SMN2LMNATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11760738-B2 Anisotropic copoly(imide oxetane) coatings and articles of manufacture, copoly(imide oxetane)s containing pendant fluorocarbon moieties, oligomers and processes therefor United States of America as represented by the Adminstrator of NASA (US) 2023-09-19 US disclosed
US-20220017479-A1 ANISOTROPIC COPOLY(IMIDE OXETANE) COATINGS AND ARTICLES OF MANUFACTURE, COPOLY(IMIDE OXETANE)S CONTAINING PENDANT FLUOROCARBON MOIETIES, OLIGOMERS AND PROCESSES THEREFOR UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA 2022-01-20 US disclosed
US-11130742-B2 Anisotropic copoly(imide oxetane) coatings and articles of manufacture, copoly(imide oxetane)s containing pendant fluorocarbon moieties, oligomers and processes therefor UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (US) 2021-09-28 US disclosed
US-10808079-B2 Synthesis of copolyimides containing fluorine and silicon surface modifying agents UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (US) 2020-10-20 US disclosed
US-20200247770-A1 ANISOTROPIC COPOLY(IMIDE OXETANE) COATINGS AND ARTICLES OF MANUFACTURE, COPOLY(IMIDE OXETANE)S CONTAINING PENDANT FLUOROCARBON MOIETIES, OLIGOMERS AND PROCESSES THEREFOR UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA 2020-08-06 US disclosed
US-10626098-B2 Anisotropic copoly(imide oxetane) coatings and articles of manufacture, copoly (imide oxetane)s containing pendant fluorocarbon moieties, oligomers and processes therefor UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (US) 2020-04-21 US disclosed
US-20180118702-A1 ANISOTROPIC COPOLY(IMIDE OXETANE) COATINGS AND ARTICLES OF MANUFACTURE, COPOLY(IMIDE OXETANE)S CONTAINING PENDANT FLUOROCARBON MOIETIES, OLIGOMERS AND PROCESSES THEREFOR UNITES STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA 2018-05-03 US disclosed
US-9822088-B2 Anisotropic copoly(imide oxetane) coatings and articles of manufacture, copoly(imide oxetane)s containing pendant fluorocarbon moieties, oligomers and processes therefor THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (US) 2017-11-21 US disclosed
WO-2016160512-A1 SYNTHESIS OF COPOLYIMIDES CONTAINING FLUORINE AND SILICON SURFACE MODIFYING AGENTS USA, as represented by the Administrator of the National Aeronautics and Space Administration (US) 2016-10-06 WO disclosed
US-20160280858-A1 Synthesis of Copolyimides Containing Fluorine and Silicon Surface Modifying Agents NATIONAL INSTITUTE OF AEROSPACE 2016-09-29 US disclosed
US-7691471-B2 Polycyclic polyimides and compositions and methods relating thereto E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-04-06 US disclosed
US-20090263640-A1 POLYCYCLIC POLYIMIDES AND COMPOSITIONS AND METHODS RELATING THERETO E.I. DU PONT DE NEMOURS AND COMPANY (US) 2009-10-22 US disclosed
US-20090226642-A1 LOW COLOR POLYIMIDE COMPOSITIONS USEFUL IN OPTICAL TYPE APPLICATIONS AND METHODS AND COMPOSITIONS RELATING THERETO E. I. DU PONT DE NEMOURS AND COMPANY (US) 2009-09-10 US disclosed
US-7572878-B2 Showing improved thermal stability properties in conjunction with improved optical transparency making these polyimides useful in electronic device applications; replacement for quartz or glass in optical display devices or the like E. I. DU PONT DE NEMOURS AND COMPANY (US) 2009-08-11 US disclosed
US-7550194-B2 Low color polyimide compositions useful in optical type applications and methods and compositions relating thereto E. I. DU PONT DE NEMOURS AND COMPANY (US) 2009-06-23 US disclosed
EP-1764381-B1 Polycyclic polyimides and compositions and their corresponding polyamic acids DU PONT (US) 2008-06-18 EP disclosed
US-20080138537-A1 Low color polyimide compositions useful in optical type applications and methods and compositions relating thereto U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2008-06-12 US disclosed
US-20070066734-A1 Polycyclic polyimides and compositions and methods relating thereto U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2007-03-22 US disclosed
EP-1764381-A1 Polycyclic polyimides and compositions and their corresponding polyamic acids E.I.Du pont de nemours and company (US) 2007-03-21 EP disclosed
EP-1749850-A1 Low color polyimide compositions useful in optical type applications and methods and compositions related thereto E.I. DUPONT DE NEMOURS AND COMPANY (US) 2007-02-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180118702-A1 ANISOTROPIC COPOLY(IMIDE OXETANE) COATINGS AND ARTICLES OF MANUFACTURE, COPOLY(IMIDE OXETANE)S CONTAINING PENDANT FLUOROCARBON MOIETIES, OLIGOMERS AND PROCESSES THEREFOR MACF1, OR51E2, FOS RAB9A 911/4885NPC1 1472/4885SMN1; SMN2 3121/4885
US-11760738-B2 Anisotropic copoly(imide oxetane) coatings and articles of manufacture, copoly(imide oxetane)s containing pendant fluorocarbon moieties, oligomers and processes therefor MACF1, OR51E2, FOS RAB9A 911/4885NPC1 1472/4885SMN1; SMN2 3121/4885
US-20200247770-A1 ANISOTROPIC COPOLY(IMIDE OXETANE) COATINGS AND ARTICLES OF MANUFACTURE, COPOLY(IMIDE OXETANE)S CONTAINING PENDANT FLUOROCARBON MOIETIES, OLIGOMERS AND PROCESSES THEREFOR MACF1, OR51E2, FOS RAB9A 911/4885NPC1 1472/4885SMN1; SMN2 3121/4885
US-10626098-B2 Anisotropic copoly(imide oxetane) coatings and articles of manufacture, copoly (imide oxetane)s containing pendant fluorocarbon moieties, oligomers and processes therefor MACF1, OR51E2, FOS RAB9A 911/4885NPC1 1472/4885SMN1; SMN2 3121/4885
US-11130742-B2 Anisotropic copoly(imide oxetane) coatings and articles of manufacture, copoly(imide oxetane)s containing pendant fluorocarbon moieties, oligomers and processes therefor MACF1, OR51E2, FOS RAB9A 911/4885NPC1 1472/4885SMN1; SMN2 3121/4885
US-20220017479-A1 ANISOTROPIC COPOLY(IMIDE OXETANE) COATINGS AND ARTICLES OF MANUFACTURE, COPOLY(IMIDE OXETANE)S CONTAINING PENDANT FLUOROCARBON MOIETIES, OLIGOMERS AND PROCESSES THEREFOR MACF1, OR51E2, FOS RAB9A 911/4885NPC1 1472/4885SMN1; SMN2 3121/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.