Sugi Predict

Sugi Predict / Compounds / SCHEMBL3279685

SCHEMBL3279685

SCHEMBL3279685

O=[N+]([O-])c1ccc2nnn(O)c2c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 3/20 0.52
▸ MAPK1 P28482 2/20 0.52
▸ ALDH1A1 P00352 4/20 0.50
▸ GAA P10253 3/20 0.47
▸ MGAM O43451 2/20 0.47
▸ AMY1A P0DUB6 2/20 0.47
▸ SI P14410 2/20 0.47
▸ MGAM2 Q2M2H8 2/20 0.47
▸ ATM Q13315 2/20 0.46
▸ POLB P06746 1/20 0.46
▸ FGFR1 P11362 1/20 0.46
▸ NSD2 O96028 1/20 0.45
▸ TXNRD1 Q16881 1/20 0.45
▸ TXNRD3 Q86VQ6 1/20 0.45
▸ TXNRD2 Q9NNW7 1/20 0.45
▸ KMT2A Q03164 3/20 0.44
▸ MEN1 O00255 2/20 0.44
▸ CYP3A4 P08684 1/20 0.42
▸ NAMPT P43490 1/20 0.42
▸ XDH P47989 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dinitrophenylene SCHEMBL27527572 0.81 ATM (0.62) MAPTMAPK1ALDH1A1GAAMGAM
SCHEMBL11458726 0.81 FGFR1 (0.47) MAPTALDH1A1GAAMGAMAMY1A
SCHEMBL19911559 0.80 ALDH1A1 (0.46) MAPTALDH1A1GAAMGAMAMY1A
SCHEMBL922709 0.80 NSD2 (0.61) MAPTALDH1A1GAAMGAMAMY1A
SCHEMBL19911578 0.78 MGAM (0.52) MAPK1ALDH1A1GAAMGAMAMY1A
SCHEMBL19911557 0.78 FGFR1 (0.43) MAPTALDH1A1GAAMGAMAMY1A
SCHEMBL31018277 0.77 MGAM (0.48) MAPTALDH1A1GAAMGAMAMY1A
P-Nitrophenol SCHEMBL22188691 0.77 ATM (0.60) MAPTMAPK1ALDH1A1GAAMGAM
SCHEMBL7621563 0.76 HTT (0.45) MAPTMAPK1ALDH1A1GAAPOLB
SCHEMBL19911576 0.76 ALDH1A1 (0.47) MAPTALDH1A1GAAMGAMAMY1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9475916-B2 Process for curing surface-coating compositions ALLNEX AUSTRIA GMBH (AT) 2016-10-25 — — US claimed
US-20140356540-A1 PROCESS FOR CURING SURFACE-COATING COMPOSITIONS CYTEC AUSTRIA GMBH (AT) 2014-12-04 — — US claimed
US-7807821-B1 Method for the synthesis of nucleic acid without protecting base moiety JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2010-10-05 — — US claimed
EP-1721908-A1 NOVEL METHOD OF SYNTHESIZING NUCLEIC ACID WITHOUT PROTECTING NUCLEOTIDE BASES Japan Science and Technology Agency (JP) 2006-11-15 — — EP claimed
EP-1092762-B1 Storage stable compositions comprising mediators, peroxide compounds and pH stabilizers, and their use in enzymatic bleaching systems BAYER CHEMICALS AG (DE) 2004-12-08 — — EP claimed
US-6380142-B1 FOR USE IN ENZYMATIC TWO-COMPONENT BLEACHING SYSTEMS BAYER AKTIENGESELLSCHAFT (DE) 2002-04-30 — — US claimed
EP-1092762-A1 Storage stable compositions comprising mediators, peroxide compounds and pH stabilizers, and their use in enzymatic bleaching systems Bayer Aktiengesellschaft (DE) 2001-04-18 — — EP claimed
US-4242507-A Sulfonic acid esters FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1980-12-30 — — US claimed
US-20260137765-A1 METHODS OF PRODUCING SHIGA TOXIN B-SUBUNIT (STXB) MONOMERS AND OLIGOMERS, AND USES THEREOF INSTITUT CURIE (FR) 2026-05-21 — — US disclosed
US-12527854-B2 Methods of producing Shiga toxin B-subunit (STxB) monomers and oligomers, and uses thereof INSTITUT CURIE (FR) 2026-01-20 — — US disclosed
EP-3604305-B1 NOVEL PYRIDONE CARBOXYLIC ACID DERIVATIVE OR SALT THEREOF WAKUNAGA PHARMA CO LTD (JP) 2024-08-28 — — EP disclosed
EP-3856164-B1 MORPHIC FORMS OF COMPLEMENT FACTOR D INHIBITORS ACHILLION PHARMACEUTICALS INC (US) 2024-08-07 — — EP disclosed
US-11807627-B2 Morphic forms of complement factor D inhibitors Achillon Pharmaceuticals, Inc. (US) 2023-11-07 — — US disclosed
US-20230331751-A1 STEREOSELECTIVE MANUFACTURE OF SELECTED PURINE PHOSPHORAMIDATES Atea Pharmaceuticals, Inc. (US) 2023-10-19 — — US disclosed
US-4240822-A HERBICIDES AMERICAN CYANAMID COMPANY (US) 1980-12-23 — — US disclosed
US-4212976-A ANTIARTHRITIC AGENTS MERCK & CO., INC. (US) 1980-07-15 — — US disclosed
EP-0002774-A1 Process for acylating 7aminocephem derivatives HOECHST AKTIENGESELLSCHAFT (DE) 1979-07-11 — — EP disclosed
US-4066636-A METHOD OF HARDENING GELATIN FUJI PHOTO FILM CO., LTD. (JA) 1978-01-03 — — US disclosed
US-4057637-A RHEUMATOID ARTHRITIS MERCK & CO., INC. (US) 1977-11-08 — — US disclosed
US-3971797-A ANTIARTHRITIC MERCK & CO., INC. (US) 1976-07-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12527854-B2 Methods of producing Shiga toxin B-subunit (STxB) monomers and oligomers, and uses thereof STXBP1, RNGTT, UPF1 MAPT 2925/4885MAPK1 4051/4885ALDH1A1 4838/4885
US-11807627-B2 Morphic forms of complement factor D inhibitors CFD, CFH, CFB MAPT 908/4885MAPK1 2284/4885ALDH1A1 4444/4885
US-20260137765-A1 METHODS OF PRODUCING SHIGA TOXIN B-SUBUNIT (STXB) MONOMERS AND OLIGOMERS, AND USES THEREOF STXBP1, HBB, UPF1 MAPT 3405/4885MAPK1 3827/4885ALDH1A1 4710/4885
US-20230331751-A1 STEREOSELECTIVE MANUFACTURE OF SELECTED PURINE PHOSPHORAMIDATES NUDT1, PNP, ATIC MAPT 3657/4885MAPK1 878/4885ALDH1A1 946/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.