SCHEMBL3279903

SCHEMBL3279903

Cc1ccc(S(=O)(=O)O/N=[C]\c2ccccc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 2/20 0.46
▸ KMT2A Q03164 2/20 0.46
▸ ALDH1A1 P00352 8/20 0.44
▸ VDR P11473 1/20 0.43
▸ HTT P42858 4/20 0.42
▸ SMN1; SMN2 Q16637 2/20 0.42
▸ LMNA P02545 6/20 0.42
▸ MAPT P10636 5/20 0.42
▸ XBP1 P17861 5/20 0.42
▸ MPI P34949 5/20 0.42
▸ NPSR1 Q6W5P4 5/20 0.42
▸ TDP1 Q9NUW8 4/20 0.42
▸ HSP90AA1 P07900 3/20 0.42
▸ MAPK1 P28482 3/20 0.42
▸ RAB9A P51151 3/20 0.42
▸ PKM P14618 3/20 0.42
▸ L3MBTL1 Q9Y468 1/20 0.42
▸ CA12 O43570 3/20 0.40
▸ CA9 Q16790 3/20 0.40
▸ CA1 P00915 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3279910 1.00 MEN1 (0.46) MEN1KMT2AALDH1A1VDRHTT
SCHEMBL10643770 0.84 ESR1 (0.40) MEN1KMT2AALDH1A1LMNAMAPT
SCHEMBL3281140 0.84 TDP1 (0.47) MEN1KMT2AALDH1A1SMN1; SMN2MAPT
SCHEMBL3281138 0.84 TDP1 (0.47) MEN1KMT2AALDH1A1SMN1; SMN2MAPT
SCHEMBL3278594 0.80 CA2 (0.44) MEN1KMT2AALDH1A1HTTSMN1; SMN2
SCHEMBL3278596 0.80 CA2 (0.44) MEN1KMT2AALDH1A1HTTSMN1; SMN2
SCHEMBL3280059 0.78 ALDH1A1 (0.43) ALDH1A1HTTSMN1; SMN2LMNAMAPT
SCHEMBL3280063 0.78 ALDH1A1 (0.43) ALDH1A1HTTSMN1; SMN2LMNAMAPT
SCHEMBL28706040 0.78 ALDH1A1 (0.47) MEN1KMT2AALDH1A1VDRHTT
SCHEMBL3279887 0.77 TDP1 (0.51) MEN1KMT2AALDH1A1HTTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7897319-B2 Positive resist composition and method of forming resist pattern TOKYO OHKA KOGYO CO., LTD. (JP) 2011-03-01 — — US disclosed
US-7700259-B2 Polymer compound, photoresist composition containing such polymer compound, and method for forming resist pattern TOKYO OHKA KOGYO CO., LTD. (JP) 2010-04-20 — — US disclosed
US-20070259273-A1 Positive Resist Composition and Method of Forming Resist Pattern TOKYO OHKA KOGYO CO., LTD. (JP) 2007-11-08 — — US disclosed
US-20070224520-A1 Polymer Compound, Photoresist Composition Containing Such Polymer Compound, and Method for Forming Resist Pattern TOKYO OHKA KOGYO CO., LTD. (JP) 2007-09-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070224520-A1 Polymer Compound, Photoresist Composition Containing Such Polymer Compound, and Method for Forming Resist Pattern ADH1A, ADH1C, POLR1A MEN1 3450/4885KMT2A 1048/4885ALDH1A1 56/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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