SCHEMBL3283783

SCHEMBL3283783

Cc1cccc(Sc2ccccc2C)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR1A P08908 3/20 0.53
HTR3A P46098 3/20 0.53
AR P10275 2/20 0.45
IDO1 P14902 2/20 0.45
ACHE P22303 1/20 0.42
MAPT P10636 2/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
KDM4E B2RXH2 1/20 0.42
GRM5 P41594 1/20 0.41
HPGD P15428 3/20 0.40
HTT P42858 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
ICAM1 P05362 1/20 0.40
SELE P16581 1/20 0.40
HAO1 Q9UJM8 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.39
SLC6A2 P23975 1/20 0.38
SLC6A4 P31645 1/20 0.38
SLC6A3 Q01959 1/20 0.38
HTR2C P28335 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9488050 0.86 HTR1A (0.48) HTR1AHTR3AARIDO1ACHE
SCHEMBL9487673 0.84 HTR1A (0.45) HTR1AHTR3AIDO1ACHEMAPT
SCHEMBL14306498 0.83 AR (0.44) HTR1AHTR3AARIDO1ACHE
SCHEMBL9488631 0.83 AR (0.46) HTR1AHTR3AARIDO1ACHE
SCHEMBL25704500 0.81 SLC6A2 (0.58) ARIDO1L3MBTL1KDM4EGRM5
SCHEMBL20222309 0.81 HTR1A (0.50) HTR1AHTR3AIDO1ACHEMAPT
SCHEMBL20845202 0.81 AR (0.43) HTR1AHTR3AARIDO1L3MBTL1
SCHEMBL2876479 0.81 L3MBTL1 (0.50) HTR1AHTR3AARACHEMAPT
SCHEMBL29580858 0.81 L3MBTL1 (0.50) HTR1AHTR3AARACHEMAPT
SCHEMBL575896 0.80 ACHE (0.58) HTR1AHTR3AIDO1ACHEMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9469604-B2 Method of manufacturing sulfonium salt TOYO GOSEI CO., LTD. (JP) 2016-10-18 US claimed
US-9650456-B2 Process for producing polydienes BRIDGESTONE CORPORATION (JP) 2017-05-16 US disclosed
US-9469604-B2 Method of manufacturing sulfonium salt TOYO GOSEI CO., LTD. (JP) 2016-10-18 US disclosed
US-20160068477-A1 METHOD OF MANUFACTURING SULTONIUM SALT TOYO GOSEI CO., LTD. (JP) 2016-03-10 US disclosed
EP-2825574-B1 PROCESS FOR PRODUCING POLYDIENES BRIDGESTONE CORP (JP) 2016-02-24 EP disclosed
US-20150031845-A1 Process For Producing Polydienes BRIDGESTONE CORPORATION (JP) 2015-01-29 US disclosed
EP-2825574-A1 PROCESS FOR PRODUCING POLYDIENES Bridgestone Corporation (JP) 2015-01-21 EP disclosed
WO-2013138270-A1 PROCESS FOR PRODUCING POLYDIENES BRIDGESTSONE CORPORATION (JP) 2013-09-19 WO disclosed
US-7709548-B2 Method for manufacturing monosulfonium salt, cationic polymerization initiator, curable composition, and cured product SAN-APRO LIMITED (JP) 2010-05-04 US disclosed
US-20090163723-A1 METHOD FOR PRODUCING SULFONIUM FLUORINATED ALKYLFLUOROPHOSPHATE SAN-APRO LIMITED (JP) 2009-06-25 US disclosed
EP-1350789-B1 PROCESS FOR PRODUCING SULFONIUM SALT SAN APRO LTD (JP) 2008-06-25 EP disclosed
US-20080108720-A1 Method for manufacturing monosulfonium salt, cationic polymerization initiator, curable composition, and cured product DATE MASASHI 2008-05-08 US disclosed
EP-1640363-B1 PROCESS FOR PRODUCTION OF MONOSULFONIUM SALTS, CATIONIC POLYMERIZATION INITIATORS, CURABLE COMPOSITIONS, AND PRODUCTS OF CURING SAN APRO LTD (JP) 2008-01-16 EP disclosed
US-20060247401-A1 Process for production of monosulfonium salts, cationic polymerization initiators, curable compositions, and products of curing SAN-APRO LIMITED (JP) 2006-11-02 US disclosed
US-7060858-B2 Method for manufacturing sulfonium salts SAN-APRO LIMITED (JP) 2006-06-13 US disclosed
EP-1640363-A1 PROCESS FOR PRODUCTION OF MONOSULFONIUM SALTS, CATIONIC POLYMERIZATION INITIATORS, CURABLE COMPOSITIONS, AND PRODUCTS OF CURING San-Apro Limited (JP) 2006-03-29 EP disclosed
US-20040030158-A1 Method for manufacturing sulfonium salts SAN-APRO LIMITED (JP) 2004-02-12 US disclosed
EP-1350789-A1 PROCESS FOR PRODUCING SULFONIUM SALT San-Apro Limited (JP) 2003-10-08 EP disclosed
US-5250657-A Process for preparing polyarylene thioether SEISAN KAIHATSU KAGAKU KENKYUSHO (JP) 1993-10-05 US disclosed
EP-0440106-A2 Process for preparing polyarylene thioethers SEISAN KAIHATSU KAGAKU KENKYUSHO (JP) 1991-08-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060247401-A1 Process for production of monosulfonium salts, cationic polymerization initiators, curable compositions, and products of curing RPS6, SPIN4, SRM HTR1A 4183/4885HTR3A 4786/4885AR 3511/4885
US-20040030158-A1 Method for manufacturing sulfonium salts MLX, STS, SULT1A1 HTR1A 1713/4885HTR3A 3119/4885AR 1457/4885
US-20090163723-A1 METHOD FOR PRODUCING SULFONIUM FLUORINATED ALKYLFLUOROPHOSPHATE ARSA, SCO2, DOHH HTR1A 3175/4885HTR3A 2650/4885AR 12/4885
US-20080108720-A1 Method for manufacturing monosulfonium salt, cationic polymerization initiator, curable composition, and cured product SPIN4, RPS6, SRM HTR1A 4406/4885HTR3A 4796/4885AR 3539/4885
US-20160068477-A1 METHOD OF MANUFACTURING SULTONIUM SALT STS, SULT1A1, ARSA HTR1A 3074/4885HTR3A 2966/4885AR 2653/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.