SCHEMBL3285247

SCHEMBL3285247

Brc1cccc(-c2ccccc2Sc2ccccc2-c2cccc(Br)c2)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 6/20 0.42
NPC1 O15118 5/20 0.42
TSHR P16473 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
TP53 P04637 1/20 0.42
MAOB P27338 2/20 0.41
ALDH1A1 P00352 5/20 0.40
MAPT P10636 4/20 0.40
HPGD P15428 3/20 0.40
HK1 P19367 1/20 0.40
HKDC1 Q2TB90 1/20 0.40
MAOA P21397 1/20 0.40
GABRA1 P14867 1/20 0.39
GABRG2 P18507 1/20 0.39
GABRB3 P28472 1/20 0.39
GABRA5 P31644 1/20 0.39
GABRA3 P34903 1/20 0.39
BIRC5 O15392 1/20 0.39
MEN1 O00255 4/20 0.38
KMT2A Q03164 4/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5805651 0.83 RAB9A (0.50) RAB9ANPC1TSHRSMN1; SMN2TP53
SCHEMBL29398181 0.83 RAB9A (0.50) RAB9ANPC1TSHRSMN1; SMN2TP53
SCHEMBL16173656 0.81 RAB9A (0.48) RAB9ANPC1TSHRSMN1; SMN2TP53
SCHEMBL2278862 0.79 ALDH1A1 (0.52) RAB9ANPC1TSHRSMN1; SMN2TP53
SCHEMBL8588225 0.77 ALDH1A1 (0.48) RAB9ANPC1TSHRSMN1; SMN2TP53
SCHEMBL29671005 0.77 ALDH1A1 (0.62) RAB9ANPC1TSHRSMN1; SMN2TP53
SCHEMBL16383438 0.77 ALDH1A1 (0.62) RAB9ANPC1TSHRSMN1; SMN2TP53
SCHEMBL4142770 0.77 ALDH1A1 (0.50) RAB9ANPC1TSHRSMN1; SMN2TP53
SCHEMBL4121500 0.76 TAAR1 (0.42) SMN1; SMN2TP53MAOBMAPTHPGD
SCHEMBL3282075 0.76 TDO2 (0.42) RAB9ANPC1TSHRSMN1; SMN2TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9469604-B2 Method of manufacturing sulfonium salt TOYO GOSEI CO., LTD. (JP) 2016-10-18 US claimed
US-9469604-B2 Method of manufacturing sulfonium salt TOYO GOSEI CO., LTD. (JP) 2016-10-18 US disclosed
US-20160068477-A1 METHOD OF MANUFACTURING SULTONIUM SALT TOYO GOSEI CO., LTD. (JP) 2016-03-10 US disclosed
EP-2236488-A1 Materials, methods and uses for photochemical generation of acids and/or radical species The Arizona Board of Regents on behalf of the University of Arizona (US) 2010-10-06 EP disclosed
US-7709548-B2 Method for manufacturing monosulfonium salt, cationic polymerization initiator, curable composition, and cured product SAN-APRO LIMITED (JP) 2010-05-04 US disclosed
US-20090163723-A1 METHOD FOR PRODUCING SULFONIUM FLUORINATED ALKYLFLUOROPHOSPHATE SAN-APRO LIMITED (JP) 2009-06-25 US disclosed
US-7459106-B2 Materials, methods, and uses for photochemical generation of acids and/or radical species THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) 2008-12-02 US disclosed
US-20080249270-A1 Method for manufacturing monosulfonium salt, cationic polymerization initiator, curable composition, and cured product DATE MASASHI 2008-10-09 US disclosed
EP-1953139-A1 METHOD FOR PRODUCING FLUORINATED SULFONIUM ALKYLFLUOROPHOSPHATE San-Apro Ltd. (JP) 2008-08-06 EP disclosed
EP-1350789-B1 PROCESS FOR PRODUCING SULFONIUM SALT SAN APRO LTD (JP) 2008-06-25 EP disclosed
EP-1390664-A4 MATERIALS, METHODS, AND USES FOR PHOTOCHEMICAL GENERATION OF ACIDS AND/OR RADICAL SPECIES UNIV ARIZONA (US) 2008-01-02 EP disclosed
US-20060247401-A1 Process for production of monosulfonium salts, cationic polymerization initiators, curable compositions, and products of curing SAN-APRO LIMITED (JP) 2006-11-02 US disclosed
US-7060858-B2 Method for manufacturing sulfonium salts SAN-APRO LIMITED (JP) 2006-06-13 US disclosed
EP-1640363-A1 PROCESS FOR PRODUCTION OF MONOSULFONIUM SALTS, CATIONIC POLYMERIZATION INITIATORS, CURABLE COMPOSITIONS, AND PRODUCTS OF CURING San-Apro Limited (JP) 2006-03-29 EP disclosed
CN-1684944-A method for copper-catalyzed formation of carbon-heteroatom and carbon-carbon bonds MASSACHUSETTS INST TECHNOLOGY (US) 2005-10-19 CN disclosed
US-20050173683-A1 Materials, methods, and uses for photochemical generation of acids and/or radical species THE ARIZ BD OF REGENTS ON BEHALF OF THE UNIV OF AZ (US) 2005-08-11 US disclosed
EP-1390664-A1 MATERIALS, METHODS, AND USES FOR PHOTOCHEMICAL GENERATION OF ACIDS AND/OR RADICAL SPECIES The Arizona Board of Regents (US) 2004-02-25 EP disclosed
US-20040030158-A1 Method for manufacturing sulfonium salts SAN-APRO LIMITED (JP) 2004-02-12 US disclosed
EP-1350789-A1 PROCESS FOR PRODUCING SULFONIUM SALT San-Apro Limited (JP) 2003-10-08 EP disclosed
WO-2002079691-A1 MATERIALS, METHODS, AND USES FOR PHOTOCHEMICAL GENERATION OF ACIDS AND/OR RADICAL SPECIES THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) 2002-10-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060247401-A1 Process for production of monosulfonium salts, cationic polymerization initiators, curable compositions, and products of curing RPS6, SPIN4, SRM RAB9A 4357/4885NPC1 4800/4885TSHR 3341/4885
US-20040030158-A1 Method for manufacturing sulfonium salts MLX, STS, SULT1A1 RAB9A 3146/4885NPC1 2763/4885TSHR 3172/4885
US-20090163723-A1 METHOD FOR PRODUCING SULFONIUM FLUORINATED ALKYLFLUOROPHOSPHATE ARSA, SCO2, DOHH RAB9A 1097/4885NPC1 701/4885TSHR 158/4885
US-20080249270-A1 Method for manufacturing monosulfonium salt, cationic polymerization initiator, curable composition, and cured product SPIN4, RPS6, SRM RAB9A 4201/4885NPC1 4750/4885TSHR 3545/4885
US-20160068477-A1 METHOD OF MANUFACTURING SULTONIUM SALT STS, SULT1A1, ARSA RAB9A 1736/4885NPC1 3716/4885TSHR 1574/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.