Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1655866 | 0.72 | FFAR3 (0.32) | — | |
| SCHEMBL28968497 | 0.63 | CA4 (0.33) | — | |
| SCHEMBL31220423 | 0.61 | CA4 (0.38) | — | |
| SCHEMBL5886409 | 0.61 | CA4 (0.38) | — | |
| SCHEMBL11485145 | 0.61 | CA4 (0.38) | — | |
| SCHEMBL5667256 | 0.61 | CYP2C19 (0.32) | — | |
| SCHEMBL624360 | 0.59 | — | — | |
| SCHEMBL9309197 | 0.59 | CA4 (0.35) | — | |
| SCHEMBL30932964 | 0.57 | CYP3A4 (0.39) | — | |
| SCHEMBL28968487 | 0.57 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7700802-B2 | by utilizing the difference in solubility between a neutralized salt of the endo isomer and a neutral salt of the exo isomer of a dicarboxylic acid having a norbornene or norbornane structure; mixing the above endo and exo mixture with NaOH and a solvent, filtering to separate liquid and solid phase | HITACHI CHEMICAL CO., LTD. (JP) | 2010-04-20 | — | — | US | disclosed |
| US-20070142668-A1 | Method of separating stereoisomers of dicarboxylic acid having norbornene or norbornane structure, or derivative thereof | HITACHI CHEMICAL CO., LTD. (JP) | 2007-06-21 | — | — | US | disclosed |
| EP-1669342-A1 | METHOD OF SEPARATING STEREOISOMERS OF NORBORNENE, DICARBOXYLIC ACID HAVING NORBORNANE STRUCTURE, OR DERIVATIVE THEREOF | Hitachi Chemical Co., Ltd. (JP) | 2006-06-14 | — | — | EP | disclosed |