Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT1 | P17948 | 5/20 | 0.73 |
| ▸ | FLT4 | P35916 | 5/20 | 0.73 |
| ▸ | KDR | P35968 | 5/20 | 0.73 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.73 |
| ▸ | MEN1 | O00255 | 1/20 | 0.69 |
| ▸ | LMNA | P02545 | 1/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.69 |
| ▸ | BCL2L1 | Q07817 | 4/20 | 0.58 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.58 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.55 |
| ▸ | P4HTM | Q9NXG6 | 3/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.54 |
| ▸ | EGFR | P00533 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8424044 | 0.86 | FLT1 (0.73) | FLT1FLT4KDRL3MBTL1MEN1 | |
| SCHEMBL174010 | 0.86 | FLT1 (0.77) | FLT1FLT4KDRL3MBTL1MEN1 | |
| SCHEMBL5931288 | 0.86 | FLT1 (0.71) | FLT1FLT4KDRL3MBTL1MEN1 | |
| SCHEMBL9176247 | 0.85 | FLT1 (1.00) | FLT1FLT4KDRL3MBTL1MEN1 | |
| Potassium SCHEMBL30358590 | 0.84 | FLT1 (0.74) | FLT1FLT4KDRL3MBTL1MEN1 | |
| SCHEMBL29011132 | 0.84 | FLT1 (0.74) | FLT1FLT4KDRL3MBTL1MEN1 | |
| SCHEMBL9967798 | 0.83 | FLT1 (0.69) | FLT1FLT4KDRL3MBTL1MEN1 | |
| SCHEMBL376340 | 0.83 | MEN1 (0.73) | FLT1FLT4KDRL3MBTL1MEN1 | |
| SCHEMBL3824815 | 0.82 | FLT1 (0.53) | FLT1FLT4KDRL3MBTL1MEN1 | |
| SCHEMBL3306626 | 0.81 | FLT1 (0.76) | FLT1FLT4KDRL3MBTL1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3055292-B1 | PROCESS FOR PREPARING 4-[[(BENZOYL)AMINO]SULPHONYL]BENZOYL CHLORIDES AND PREPARATION OF ACYLSULPHAMOYLBENZAMIDES | BAYER CROPSCIENCE AG (DE) | 2017-08-16 | — | — | EP | claimed |
| US-9725409-B2 | Process for preparing 4[[(benzoyl)amino]sulphonyl]benzoyl chlorides and preparation of acylsulphamoylbenzamides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-08-08 | — | — | US | claimed |
| EP-3055292-A1 | PROCESS FOR PREPARING 4-[[(BENZOYL)AMINO]SULPHONYL]BENZOYL CHLORIDES AND PREPARATION OF ACYLSULPHAMOYLBENZAMIDES | Bayer CropScience Aktiengesellschaft (DE) | 2016-08-17 | — | — | EP | claimed |
| US-20160214929-A1 | PROCESS FOR PREPARING 4[[(BENZOYL)AMINO]SULPHONYL]BENZOYL CHLORIDES AND PREPARATION OF ACYLSULPHAMOYLBENZAMIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2016-07-28 | — | — | US | claimed |
| CN-105636942-A | Process for preparing 4- [ [ (benzoyl) amino ] sulfonyl ] benzoyl chloride and preparation of acylsulfamoylbenzamides | BAYER CROPSCIENCE AG | 2016-06-01 | — | — | CN | claimed |
| WO-2015052156-A1 | PROCESS FOR PREPARING 4-[[(BENZOYL)AMINO]SULPHONYL]BENZOYL CHLORIDES AND PREPARATION OF ACYLSULPHAMOYLBENZAMIDES | BAYER CROPSCIENCE AG (DE) | 2015-04-16 | — | — | WO | claimed |
| CN-116606230-A | Preparation method of acyl sulfamoyl benzamide | 拜耳作物科学股份公司 | 2023-08-18 | — | — | CN | disclosed |
| US-10421713-B2 | Process for preparing 4[[(benzoyl)amino]sulphonyl]benzoyl chlorides and preparation of acylsulphamoylbenzamides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-09-24 | — | — | US | disclosed |
| US-10421713-B2 | Process for preparing 4[[(benzoyl)amino]sulphonyl]benzoyl chlorides and preparation of acylsulphamoylbenzamides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-09-24 | — | — | US | disclosed |
| EP-3280699-B1 | METHOD FOR PREPARING ACYLSULFAMOYLBENZAMIDES | BAYER CROPSCIENCE AG (DE) | 2019-07-10 | — | — | EP | disclosed |
| EP-3280699-A1 | METHOD FOR PRODUCING ACYLSULFAMOYLBENZAMIDES | Bayer CropScience Aktiengesellschaft (DE) | 2018-02-14 | — | — | EP | disclosed |
| US-20170305845-A1 | PROCESS FOR PREPARING 4[[(BENZOYL)AMINO]SULPHONYL]BENZOYL CHLORIDES AND PREPARATION OF ACYLSULPHAMOYLBENZAMIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-10-26 | — | — | US | disclosed |
| US-20170305845-A1 | PROCESS FOR PREPARING 4[[(BENZOYL)AMINO]SULPHONYL]BENZOYL CHLORIDES AND PREPARATION OF ACYLSULPHAMOYLBENZAMIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-10-26 | — | — | US | disclosed |
| US-20100094052-A1 | PROCESS FOR PREPARING ACYLSULFAMOYLBENZAMIDES | BAYER CROPSCIENCE GMBH (DE) | 2010-04-15 | — | — | US | disclosed |
| EP-2119699-A1 | Process for preparing acylsulfamoylbenzamides | Bayer CropScience AG (DE) | 2009-11-18 | — | — | EP | disclosed |
| US-7608736-B2 | Chlorination a a benzenesulfamoyl compound in presence of a base | BAYER CROPSCIENCE GMBH (DE) | 2009-10-27 | — | — | US | disclosed |
| EP-1644324-B1 | PROCESS FOR PREPARING ACYLSULFAMOYLBENZAMIDES | BAYER CROPSCIENCE AG (DE) | 2009-09-30 | — | — | EP | disclosed |
| EP-1644324-A1 | PROCESS FOR PREPARING ACYLSULFAMOYLBENZAMIDES | Bayer CropScience GmbH (DE) | 2006-04-12 | — | — | EP | disclosed |
| US-20050004372-A1 | Process for preparing acylsulfamoylbenzamides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2005-01-06 | — | — | US | disclosed |
| WO-2005000797-A1 | PROCESS FOR PREPARING ACYLSULFAMOYLBENZAMIDES | BAYER CROPSCIENCE GMBH (DE) | 2005-01-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10421713-B2 | Process for preparing 4[[(benzoyl)amino]sulphonyl]benzoyl chlorides and preparation of acylsulphamoylbenzamides | SPTSSB, ACSL3, ASNS | FLT1 4548/4885FLT4 4032/4885KDR 3827/4885 |
| US-20100094052-A1 | PROCESS FOR PREPARING ACYLSULFAMOYLBENZAMIDES | SULT2A1, STS, SULT1A1 | FLT1 3530/4885FLT4 3664/4885KDR 4150/4885 |
| US-20160214929-A1 | PROCESS FOR PREPARING 4[[(BENZOYL)AMINO]SULPHONYL]BENZOYL CHLORIDES AND PREPARATION OF ACYLSULPHAMOYLBENZAMIDES | SPTSSB, STS, ACSL4 | FLT1 4564/4885FLT4 3892/4885KDR 3717/4885 |
| US-20170305845-A1 | PROCESS FOR PREPARING 4[[(BENZOYL)AMINO]SULPHONYL]BENZOYL CHLORIDES AND PREPARATION OF ACYLSULPHAMOYLBENZAMIDES | SPTSSB, STS, ACSL3 | FLT1 4546/4885FLT4 3796/4885KDR 3492/4885 |
| US-20050004372-A1 | Process for preparing acylsulfamoylbenzamides | SULT2A1, STS, SULT1A1 | FLT1 3530/4885FLT4 3664/4885KDR 4150/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.