SCHEMBL9967798

SCHEMBL9967798

CNC(=O)c1ccc(S(=O)(=O)NC(=O)c2ccccc2)cc1

nearest known ligand 0.69

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
FLT1 P17948 3/20 0.69
FLT4 P35916 3/20 0.69
KDR P35968 3/20 0.69
MEN1 O00255 1/20 0.69
LMNA P02545 1/20 0.69
KMT2A Q03164 1/20 0.69
L3MBTL1 Q9Y468 1/20 0.69
BCL2L1 Q07817 3/20 0.58
MCL1 Q07820 3/20 0.58
CA2 P00918 1/20 0.57
HTT P42858 1/20 0.56
PTGS2 P35354 3/20 0.55
P4HTM Q9NXG6 3/20 0.55
PTGS1 P23219 1/20 0.54
HDAC2 Q92769 1/20 0.52
HDAC8 Q9BY41 1/20 0.52
HDAC6 Q9UBN7 1/20 0.52
KAT6A Q92794 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15679406 0.95 FLT1 (0.61) FLT1FLT4KDRMEN1LMNA
SCHEMBL8424044 0.86 FLT1 (0.73) FLT1FLT4KDRMEN1LMNA
SCHEMBL5931288 0.86 FLT1 (0.71) FLT1FLT4KDRMEN1LMNA
SCHEMBL174010 0.86 FLT1 (0.77) FLT1FLT4KDRMEN1LMNA
SCHEMBL14585676 0.85 FLT1 (0.67) FLT1FLT4KDRMEN1LMNA
SCHEMBL5931087 0.85 PTGS2 (0.71) FLT1FLT4KDRMEN1LMNA
SCHEMBL29011132 0.84 FLT1 (0.74) FLT1FLT4KDRMEN1LMNA
Potassium SCHEMBL30358590 0.84 FLT1 (0.74) FLT1FLT4KDRMEN1LMNA
SCHEMBL3300299 0.83 FLT1 (0.73) FLT1FLT4KDRMEN1LMNA
SCHEMBL3292237 0.83 PTGS2 (0.69) FLT1FLT4KDRMEN1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 125 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230180757-A1 SUBSTITUTED ISOPHTHALIC ACID DIAMIDES AND THEIR USE AS HERBICIDES BAYER AKTIENGESELLSCHAFT (DE) 2023-06-15 US disclosed
US-20230180758-A1 SUBSTITUTED PYRROLINE-2-ONES AND THEIR USE AS HERBICIDES BAYER AKTIENGESELLSCHAFT (DE) 2023-06-15 US disclosed
US-20230167088-A1 1-PYRAZINYLPYRAZOLYL-3-OXYALKYL ACIDS AND THEIR DERIVATIVES, AND THEIR USE FOR CONTROL OF UNDESIRED PLANT GROWTH BAYER AKTIENGESELLSCHAFT (DE) 2023-06-01 US disclosed
US-20230159472-A1 SUBSTITUTED ISOPHTHALIC ACID DIAMIDES BAYER AKTIENGESELLSCHAFT (DE) 2023-05-25 US disclosed
US-20230150953-A1 SUBSTITUTED ISOPHTHALIC ACID DIAMIDES BAYER AKTIENGESELLSCHAFT (DE) 2023-05-18 US disclosed
US-10021877-B2 Substituted 5-hydroxy-2,3-diphenylpentanonitrile derivatives, processes for their preparation and their use as herbicides and/or plant growth regulators BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2018-07-17 US disclosed
US-9963431-B2 Use of quinoline derivatives for improving plant yield BAYER CROPSCIENCE AG (DE) 2018-05-08 US disclosed
US-9949485-B2 Use of acylsulfonamides for improving plant yield BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2018-04-24 US disclosed
US-20170332640-A1 USE OF 5-PHENYL- OR 5-BENZYL-2 ISOXAZOLINE-3 CARBOXYLATES FOR IMPROVING PLANT YIELD BAYER INTELLECTUAL PROPERTY GMBH (DE) 2017-11-23 US disclosed
US-9809542-B2 Spiroheterocyclically substituted tetramic acid derivatives BAYER INTELLECTUAL PROPERTY GMBH (DE) 2017-11-07 US disclosed
US-20100285964-A1 SALTS OF 2-IODO-N-[(4-METHOXY-6-METHYL-1,3, 5-TRIAZINE-2-YL) CARBAMOYL] BENZENESULFONAMIDE, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF AS HERBICIDES AND PLANT GROWTH REGULATORS BAYERCROPSCIENCE AG (DE) 2010-11-11 US disclosed
US-20100279863-A1 HERBICIDAL COMPOUNDS BASED ON N-AZINYL-N'-PYRIDYLSULFONYLUREAS BAYER CROPSCIENCE AG (DE) 2010-11-04 US disclosed
US-20100261608-A1 Geminal alkoxy/alkylspirocyclic substituted tetramate derivatives BAYER CROPSCIENCE AG (DE) 2010-10-14 US disclosed
US-20100255995-A1 HERBICIDE/AZOLE COMBINATION BAYER CROPSCIENCE AG (DE) 2010-10-07 US disclosed
US-20100248965-A1 HERBICIDAL COMBINATION BAYER CROPSCIENCE AG 2010-09-30 US disclosed
US-20100197501-A1 SUBSTITUTED 1-(THIAZOLYL)-AND 1-(ISOTHIAZOLYL)PYRAZOL-4-YLACETIC ACIDS, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES AND PLANT GROWTH REGULATORS BAYER CROPSCIENCE AG (DE) 2010-08-05 US disclosed
US-20100167935-A1 Pyrimidine derivatives and their use for controlling undesired plant growth BAYER CROPSCIENCE AG (DE) 2010-07-01 US disclosed
US-20100167934-A1 PYRIMIDINE DERIVATIVES AND THEIR USE FOR CONTROLLING UNDESIRED PLANT GROWTH BAYER CROPSCIENCE AG (DE) 2010-07-01 US disclosed
US-20100160164-A1 SUBSTITUTED 1-(DIAZINYL)PYRAZOL-4-YLACETIC ACIDS, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES AND PLANT GROWTH REGULATORS BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2010-06-24 US disclosed
US-20100062939-A1 Herbicide/Safener Combination Comprising Dimethoxytriazinyl-Substituted Difluoromethanesulfonylanilides BAYER CROPSCIENCE AG (DE) 2010-03-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (17 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230150953-A1 SUBSTITUTED ISOPHTHALIC ACID DIAMIDES DDT, ZDHHC2, DDAH1 FLT1 4039/4885FLT4 4448/4885KDR 4002/4885
US-20100255995-A1 HERBICIDE/AZOLE COMBINATION HTT, SOD1, ABAT FLT1 2877/4885FLT4 2703/4885KDR 4183/4885
US-20100167935-A1 Pyrimidine derivatives and their use for controlling undesired plant growth TYMS, TYMP, UMPS FLT1 1914/4885FLT4 2036/4885KDR 2685/4885
US-20100279863-A1 HERBICIDAL COMPOUNDS BASED ON N-AZINYL-N'-PYRIDYLSULFONYLUREAS DDT, AZI2, PDXK FLT1 1283/4885FLT4 2025/4885KDR 2243/4885
US-20230167088-A1 1-PYRAZINYLPYRAZOLYL-3-OXYALKYL ACIDS AND THEIR DERIVATIVES, AND THEIR USE FOR CONTROL OF UNDESIRED PLANT GROWTH AGPS, CBR3, HPD FLT1 1219/4885FLT4 2202/4885KDR 3422/4885
US-20100160164-A1 SUBSTITUTED 1-(DIAZINYL)PYRAZOL-4-YLACETIC ACIDS, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES AND PLANT GROWTH REGULATORS DDT, DDC, HPD FLT1 181/4885FLT4 536/4885KDR 184/4885
US-20100285964-A1 SALTS OF 2-IODO-N-[(4-METHOXY-6-METHYL-1,3, 5-TRIAZINE-2-YL) CARBAMOYL] BENZENESULFONAMIDE, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF AS HERBICIDES AND PLANT GROWTH REGULATORS MYB, INMT, AS3MT FLT1 1617/4885FLT4 1531/4885KDR 1534/4885
US-20230180757-A1 SUBSTITUTED ISOPHTHALIC ACID DIAMIDES AND THEIR USE AS HERBICIDES DDT, DAO, IDH2 FLT1 3479/4885FLT4 3943/4885KDR 3661/4885
US-10021877-B2 Substituted 5-hydroxy-2,3-diphenylpentanonitrile derivatives, processes for their preparation and their use as herbicides and/or plant growth regulators HPD, DDT, HDHD5 FLT1 837/4885FLT4 694/4885KDR 997/4885
US-20170332640-A1 USE OF 5-PHENYL- OR 5-BENZYL-2 ISOXAZOLINE-3 CARBOXYLATES FOR IMPROVING PLANT YIELD PAOX, BROX, CYP4Z1 FLT1 2994/4885FLT4 1238/4885KDR 2843/4885
US-20100197501-A1 SUBSTITUTED 1-(THIAZOLYL)-AND 1-(ISOTHIAZOLYL)PYRAZOL-4-YLACETIC ACIDS, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES AND PLANT GROWTH REGULATORS THRA, TSHR, DDT FLT1 297/4885FLT4 1006/4885KDR 742/4885
US-20230180758-A1 SUBSTITUTED PYRROLINE-2-ONES AND THEIR USE AS HERBICIDES DDT, HPD, ALDH18A1 FLT1 1667/4885FLT4 1913/4885KDR 2709/4885
US-20100248965-A1 HERBICIDAL COMBINATION DDT, AADAC, AS3MT FLT1 4211/4885FLT4 4018/4885KDR 4265/4885
US-20230159472-A1 SUBSTITUTED ISOPHTHALIC ACID DIAMIDES DDT, IDH2, DAO FLT1 4159/4885FLT4 4155/4885KDR 4135/4885
US-20100062939-A1 Herbicide/Safener Combination Comprising Dimethoxytriazinyl-Substituted Difluoromethanesulfonylanilides DDT, CYP2W1, AS3MT FLT1 2882/4885FLT4 2979/4885KDR 1537/4885
US-20100261608-A1 Geminal alkoxy/alkylspirocyclic substituted tetramate derivatives GMNN, AGXT, GEMIN5 FLT1 3026/4885FLT4 3864/4885KDR 3943/4885
US-20100167934-A1 PYRIMIDINE DERIVATIVES AND THEIR USE FOR CONTROLLING UNDESIRED PLANT GROWTH TYMS, TYMP, UMPS FLT1 2117/4885FLT4 2353/4885KDR 3073/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.