Known targets — ChEMBL curated mechanism
ABL1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB2AGTR1BCL2BCL2A1BCL2L1BCL2L10BCL2L2BCRBRAFCHRM1CHRNA10CHRNA9DRD1DRD2DRD3DRD4DRD5EGFRF2FLT1FLT4GCKGHSRGNRHRGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHTR1AHTR1BHTR1DHTR2AHTR2CHTR3AIDH2KDRKITMAOBMCL1MTTPPP4HBPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PIKFYVEROCK1ROCK2SLC18A2SLC6A2SLC6A3SLC6A4TACR1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8gyrAgyrBparCparEpol
The experimentally established mechanism targets of Tetrabuthylammonium. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A1 | O15245 | 3/20 | 0.63 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | DNM1 | Q05193 | 5/20 | 0.46 |
| ▸ | RECQL | P46063 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | LSS | P48449 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetrabuthylammonium SCHEMBL31303421 | 0.97 | SLC22A1 (0.60) | SLC22A1SLC22A2TSHRALDH1A1TP53 | |
| SCHEMBL330915 | 0.95 | SLC22A1 (0.62) | SLC22A1SLC22A2TSHRALDH1A1TP53 | |
| Tetrapentylammonium SCHEMBL306115 | 0.95 | SLC22A1 (0.63) | SLC22A1SLC22A2TSHRALDH1A1TP53 | |
| SCHEMBL331290 | 0.92 | SLC22A1 (0.65) | SLC22A1SLC22A2TSHRALDH1A1TP53 | |
| Tetrahexylammonium SCHEMBL330698 | 0.92 | SLC22A1 (0.65) | SLC22A1SLC22A2TSHRALDH1A1TP53 | |
| SCHEMBL330618 | 0.92 | SLC22A1 (0.65) | SLC22A1SLC22A2TSHRALDH1A1TP53 | |
| Tetrabuthylammonium SCHEMBL243898 | 0.92 | SLC22A1 (0.67) | SLC22A1SLC22A2TSHRALDH1A1TP53 | |
| SCHEMBL27863447 | 0.90 | SLC22A1 (0.50) | SLC22A1SLC22A2TSHRALDH1A1TP53 | |
| Tetrabuthylammonium SCHEMBL331003 | 0.90 | SLC22A1 (0.63) | SLC22A1SLC22A2TSHRALDH1A1TP53 | |
| Tetrabuthylammonium SCHEMBL9795123 | 0.90 | SLC22A1 (0.63) | SLC22A1SLC22A2TSHRALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 420 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122079810-A | Aromatic diamine and polyimide containing amido, preparation method and application thereof | — | 2026-05-26 | — | — | CN | claimed |
| US-20260045538-A1 | Catalyst for Lithium-Sulfur Batteries | UNIV NORTHEASTERN (US) | 2026-02-12 | — | — | US | claimed |
| US-20260015560-A1 | COMPOSITIONS FOR POST-CMP CLEANING OF MICROELECTRONIC DEVICES | ENTEGRIS INC (US) | 2026-01-15 | — | — | US | claimed |
| CN-119977847-A | Alkyl carboxylic acid-based18Synthesis method of F-labeled alkylsulfonyl fluoride molecule | 华中科技大学同济医学院附属同济医院 | 2025-05-13 | — | — | CN | claimed |
| CN-119841745-A | High-valence iodine (III) carboxylate18Synthesis method of F-labeled alkylsulfonyl fluoride molecule | 华中科技大学同济医学院附属同济医院 | 2025-04-18 | — | — | CN | claimed |
| CN-119823109-A | An electrochromic material electrochromic composition and electrochromic device | 吉林大学 | 2025-04-15 | — | — | CN | claimed |
| CN-118771310-A | No-drying18F-Solution, preparation method and application thereof | 四川大学华西医院 | 2024-10-15 | — | — | CN | claimed |
| CN-115807348-B | Reactive digital printing paste composition for knitted fabric and preparation method thereof | 太仓宝霓实业有限公司 | 2024-07-02 | — | — | CN | claimed |
| WO-2024081696-A2 | COMPOSITIONS CONTAINING PHASE CHANGE MATERIALS, METHODS FOR FORMING OBJECTS USING THE SAME, AND METHOD FOR USING THE SAME | PHASE CHANGE ENERGY SOLUTIONS, INC. (US) | 2024-04-18 | — | — | WO | claimed |
| CN-111117594-B | Electrochromic material and electrochromic device based on dynamic metal-ligand complexation | 吉林大学 | 2024-03-26 | — | — | CN | claimed |
| US-20100016517-A1 | POLYMERIZATION CATALYST FOR POLYTHIOURETHANE-BASED OPTICAL MATERIAL, POLYMERIZABLE COMPOSITION CONTAINING THE CATALYST, OPTICAL MATERIAL OBTAINED FROM THE COMPOSITION, AND METHOD FOR PREPARING THE OPTICAL MATERIAL | MITSUI CHEMICALS, INC (JP) | 2010-01-21 | — | — | US | claimed |
| WO-2010003548-A1 | PROCESS FOR PRODUCTION OF RADIOPHARMACEUTICALS | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-01-14 | — | — | WO | claimed |
| EP-2116558-A1 | POLYMERIZATION CATALYST FOR POLYTHIOURETHANE OPTICAL MATERIAL, POLYMERIZABLE COMPOSITION CONTAINING THE CATALYST, OPTICAL MATERIAL OBTAINED FROM THE COMPOSITION, AND METHOD FOR PRODUCING THE OPTICAL MATERIAL | Mitsui Chemicals, Inc. (JP) | 2009-11-11 | — | — | EP | claimed |
| WO-2003051894-A1 | PREPARATION OF IONIC LIQUIDS | CYTEC CANADA INC. (CA) | 2003-06-26 | — | — | WO | claimed |
| EP-0585113-B1 | Detecting an analyte in the gaseous or vapour phase by bioelectrochemical reactions and media therefor | UNIV CRANFIELD (GB) | 1999-12-15 | — | — | EP | claimed |
| EP-0600659-B1 | Toner and developer compositions with pyridinium compounds and tetrasubstituted ammonium salts as charge enhancing additives | XEROX CORP (US) | 1997-07-30 | — | — | EP | claimed |
| EP-0600659-A1 | Toner and developer compositions with pyridinium compounds and tetrasubstituted ammonium salts as charge enhancing additives | XEROX CORPORATION (US) | 1994-06-08 | — | — | EP | claimed |
| US-5304449-A | Toner and developer compositions with pyridinium compounds and tetrasubstituted ammonium salts as charge enhancing additives | XEROX CORPORATION (US) | 1994-04-19 | — | — | US | claimed |
| US-4849531-A | Process for the preparation of 2,3-epoxyamides | BAYER AKTIENGESELLSCHAFT (DE) | 1989-07-18 | — | — | US | claimed |
| EP-0244717-A2 | Process for the preparation of 2,3-epoxyamides | BAYER AG (DE) | 1987-11-11 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260015560-A1 | COMPOSITIONS FOR POST-CMP CLEANING OF MICROELECTRONIC DEVICES | TET2, ASIC1, PIEZO1 | SLC22A1 2747/4885SLC22A2 2992/4885TSHR 2647/4885 |
| US-20260045538-A1 | Catalyst for Lithium-Sulfur Batteries | KCNA4, CACNA2D4, KCNA1 | SLC22A1 799/4885SLC22A2 835/4885TSHR 339/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.