SCHEMBL331040

SCHEMBL331040

Sc1ccc(CCc2ccc(S)cc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GFER P55789 1/20 0.47
ESR1 P03372 1/20 0.47
ESR2 Q92731 1/20 0.47
IDO1 P14902 1/20 0.42
MAOA P21397 2/20 0.39
MAOB P27338 2/20 0.39
LTA4H P09960 1/20 0.38
P2RY6 Q15077 1/20 0.36
CA2 P00918 1/20 0.35
FFAR1 O14842 1/20 0.35
TAAR1 Q96RJ0 6/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2A6 P11509 1/20 0.33
CYP19A1 P11511 1/20 0.33
KDM4E B2RXH2 1/20 0.33
ALDH1A1 P00352 1/20 0.33
HTR1A P08908 1/20 0.33
ADRA2A P08913 1/20 0.33
SLC6A2 P23975 1/20 0.33
CYP2C19 P33261 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9456420 0.88 MAOB (0.56) IDO1MAOAMAOBFFAR1TAAR1
SCHEMBL22164132 0.87 HTR2A (0.44) GFERESR1ESR2IDO1MAOA
SCHEMBL8852309 0.84 ESR1 (0.44) ESR1MAOAMAOBKDM4EALDH1A1
SCHEMBL11026456 0.84 IDO1 (0.36) GFERESR1ESR2IDO1CA2
SCHEMBL2643684 0.82 TAAR1 (0.56) MAOBCA2TAAR1CYP1A2CYP2A6
SCHEMBL9320415 0.82 IDO1 (0.41) GFERESR1ESR2IDO1TAAR1
SCHEMBL186074 0.82 LPL (0.50) ESR1CA2TAAR1KDM4EALDH1A1
SCHEMBL2212372 0.82 CA2 (0.59) GFERESR1ESR2IDO1CA2
SCHEMBL20172419 0.82 MAOB (0.50) IDO1MAOAMAOBFFAR1TAAR1
Methane SCHEMBL8000953 0.80 CA2 (0.56) ESR1ESR2IDO1CA2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 418 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017025244-A1 COSMETIC PROCESS FOR TREATING KERATIN MATERIALS L'OREAL (FR) 2017-02-16 WO claimed
US-6391433-B1 None US disclosed
US-12606692-B2 Spectacle lens HOYA LENS THAILAND LTD. (TH) 2026-04-21 US disclosed
US-20260062548-A1 RUBBER-BONDED CELLULOSE FIBERS AND MANUFACTURING METHOD THEREFOR, RESIN COMPOSITION AND MANUFACTURING METHOD THEREFOR, AND CURABLE RESIN COMPOSITION KUREHA CORPORATION (JP) 2026-03-05 US disclosed
US-20260062512-A1 CURABLE COMPOSITION, CURED PRODUCT, AND METHOD FOR PRODUCING CURED PRODUCT KUREHA CORPORATION (JP) 2026-03-05 US disclosed
EP-3778170-B1 METHOD FOR MANUFACTURING OPTICAL MEMBER HOYA LENS THAILAND LTD (TH) 2026-01-28 EP disclosed
US-20250376456-A1 MONOMER FOR OPTICAL COMPONENT, POLYMERIZABLE COMPOSITION FOR OPTICAL COMPONENT, CURED PRODUCT, AND SPECTACLE LENS HOYA LENS THAILAND LTD. (TH) 2025-12-11 US disclosed
EP-4640735-A1 CURABLE RESIN COMPOSITION AND PROCESSED PRODUCT OF SAME ThreeBond Co., Ltd. (JP) 2025-10-29 EP disclosed
EP-4613263-A1 PHOTOCURABLE COMPOSITION FOR NAILS OR ARTIFICIAL NAILS ThreeBond Co., Ltd. (JP) 2025-09-10 EP disclosed
EP-4613262-A1 PHOTOCURABLE COMPOSITION FOR NAILS OR ARTIFICIAL NAILS ThreeBond Co., Ltd. (JP) 2025-09-10 EP disclosed
US-5126388-A Sulfur-containing polyurethane or polythiourethane and internal mold release agent MITSUI TOATSU CHEMICALS, INC. (JP) 1992-06-30 US disclosed
US-5059673-A bis(isocyanatomethyl)-norbornane or -4,7methonohexahydroindan e high refractive index, lightweight, high impact MITSUI TOATSU CHEMICALS, INC. (JP) 1991-10-22 US disclosed
US-5021503-A Polythiourethanes from sulfur-containing aliphatic diisocyanates and polythiols or polyols; colorless MITSUI TOATSU CHEMICALS, INC. (JP) 1991-06-04 US disclosed
US-5013496-A Polyurethane or polythiourethane MITSUI TOATSU CHEMICALS, INC. (JP) 1991-05-07 US disclosed
EP-0422836-A2 Resin for urethane lenses, lenses comprising the resin, and a process for preparation of the resin and the lenses MITSUI TOATSU CHEMICALS, Inc. (JP) 1991-04-17 EP disclosed
EP-0394495-A1 4,4'-BIS(METHACRYLOYLTHIO)DIPHENYL SULFIDE AND CURABLE COMPOSITION CONTAINING SAME SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 1990-10-31 EP disclosed
EP-0374258-A1 HIGH REFRACTIVE INDEX LENS AND METHOD FOR ITS PRODUCTION MITSUI CHEMICALS, INC. (JP) 1990-06-27 EP disclosed
EP-0330363-A2 Highly-refractive plastic lens and process for making the lens MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-08-30 EP disclosed
EP-0329387-A2 Plastic lens, and method for its preparation MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-08-23 EP disclosed
US-3979369-A DIENE POLYMER MONSANTO COMPANY (US) 1976-09-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260062548-A1 RUBBER-BONDED CELLULOSE FIBERS AND MANUFACTURING METHOD THEREFOR, RESIN COMPOSITION AND MANUFACTURING METHOD THEREFOR, AND CURABLE RESIN COMPOSITION CROCC, WASF2, DCXR GFER 301/4885ESR1 2187/4885ESR2 2244/4885
US-20250376456-A1 MONOMER FOR OPTICAL COMPONENT, POLYMERIZABLE COMPOSITION FOR OPTICAL COMPONENT, CURED PRODUCT, AND SPECTACLE LENS CRYZ, CRYAA, UACA GFER 509/4885ESR1 3622/4885ESR2 4163/4885
US-12606692-B2 Spectacle lens POT1, TCOF1, CRY1 GFER 1788/4885ESR1 2642/4885ESR2 1925/4885
US-20260062512-A1 CURABLE COMPOSITION, CURED PRODUCT, AND METHOD FOR PRODUCING CURED PRODUCT EHMT1, EHMT2, ASH2L GFER 397/4885ESR1 546/4885ESR2 686/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.