Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.56 |
| ▸ | GPR183 | P32249 | 1/20 | 0.56 |
| ▸ | HCRTR2 | O43614 | 6/20 | 0.51 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13950149 | 0.90 | KMT2A (0.57) | KMT2ANPC1CHRNA7GPR183HCRTR2 | |
| SCHEMBL3322456 | 0.88 | ALDH1A1 (0.58) | KMT2ANPC1ALDH1A1MEN1ALOX12 | |
| SCHEMBL3320913 | 0.87 | CHRNA7 (0.58) | KMT2ANPC1CHRNA7GPR183HCRTR2 | |
| SCHEMBL13361620 | 0.83 | CHRNA7 (0.55) | KMT2ANPC1CHRNA7GPR183HCRTR2 | |
| SCHEMBL3322835 | 0.82 | ALDH1A1 (0.52) | KMT2ANPC1ALDH1A1MEN1ALOX12 | |
| SCHEMBL9667825 | 0.81 | CHRNA7 (0.69) | KMT2ANPC1CHRNA7GPR183HCRTR2 | |
| SCHEMBL9668362 | 0.81 | CHRNA7 (0.69) | KMT2ANPC1CHRNA7GPR183HCRTR2 | |
| SCHEMBL9416631 | 0.80 | KMT2A (0.76) | KMT2ANPC1CHRNA7GPR183HCRTR2 | |
| SCHEMBL3056571 | 0.77 | KDM4E (0.69) | KMT2ANPC1CHRNA7GPR183HCRTR2 | |
| SCHEMBL9416605 | 0.77 | LMNA (0.75) | KMT2ANPC1CHRNA7GPR183HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100120789-A1 | Compound | STERIX LIMITED (GB) | 2010-05-13 | — | — | US | disclosed |
| US-20100120789-A1 | Compound | STERIX LIMITED (GB) | 2010-05-13 | — | — | US | disclosed |
| US-20090042929-A1 | 11-Beta-Hydroxysteroid Dehydrogenase Inhibitors | STERIX LIMITED (GB) | 2009-02-12 | — | — | US | disclosed |
| US-20090042929-A1 | 11-Beta-Hydroxysteroid Dehydrogenase Inhibitors | STERIX LIMITED (GB) | 2009-02-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090042929-A1 | 11-Beta-Hydroxysteroid Dehydrogenase Inhibitors | HSD3B1, HSD3B2, HSD11B1 | KMT2A 3083/4885NPC1 1106/4885CHRNA7 243/4885 |
| US-20100120789-A1 | Compound | NR0B2, NR0B1, NR4A1 | KMT2A 2533/4885NPC1 2474/4885CHRNA7 95/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.