Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.70 |
| ▸ | AURKA | O14965 | 1/20 | 0.70 |
| ▸ | DHFR | P00374 | 1/20 | 0.70 |
| ▸ | LMNA | P02545 | 1/20 | 0.70 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | IL1RN | P18510 | 1/20 | 0.57 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.57 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.57 |
| ▸ | G6PD | P11413 | 1/20 | 0.56 |
| ▸ | NFKBIA | P25963 | 1/20 | 0.56 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.56 |
| ▸ | METAP2 | P50579 | 1/20 | 0.56 |
| ▸ | METAP1 | P53582 | 1/20 | 0.56 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.56 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenyl(Phenylsulfonyl)Amine SCHEMBL4080552 | 0.93 | KEAP1 (0.71) | TSHRAURKADHFRLMNANPSR1 | |
| SCHEMBL31681365 | 0.89 | AURKA (0.67) | TSHRAURKADHFRLMNANPSR1 | |
| SCHEMBL2526996 | 0.84 | TSHR (0.54) | TSHRAURKADHFRLMNANPSR1 | |
| Sulfadiazine SCHEMBL30080807 | 0.82 | LMNA (1.00) | TSHRAURKADHFRLMNAALDH1A1 | |
| SCHEMBL9209077 | 0.82 | AURKA (0.69) | TSHRAURKADHFRLMNAALDH1A1 | |
| SCHEMBL6281604 | 0.82 | AURKA (0.69) | TSHRAURKADHFRLMNAALDH1A1 | |
| SCHEMBL922001 | 0.82 | AURKA (0.64) | TSHRAURKADHFRLMNANPSR1 | |
| Sulfadiazine SCHEMBL24176 | 0.82 | LMNA (1.00) | TSHRAURKADHFRLMNAALDH1A1 | |
| Sulfadiazine SCHEMBL10422849 | 0.82 | LMNA (1.00) | TSHRAURKADHFRLMNAALDH1A1 | |
| SCHEMBL12306892 | 0.82 | ALDH1A1 (0.87) | TSHRAURKADHFRLMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 119 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8354407-B2 | 2-anilino-4-(heterocyclic)amino-pyrimidines | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-01-15 | — | — | US | claimed |
| US-8097587-B2 | IGF-I protein variants for treating IGFBP-1-related disorders | GENENTECH, INC. (US) | 2012-01-17 | — | — | US | claimed |
| US-7858119-B1 | Extended release pharmaceuticals | ITELLIPHARMACEUTICS CORP. (CA) | 2010-12-28 | — | — | US | claimed |
| CN-101899010-A | Quinazol derivative, preparation method and application thereof | UNIV PLA 2ND MILITARY MEDICAL | 2010-12-01 | — | — | CN | claimed |
| US-20090227586-A1 | 2-ANILINO-4-(HETEROCYCLIC)AMINO-PYRIMIDINES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-09-10 | — | — | US | claimed |
| US-20070293494-A1 | 2-Anilino-4-(Heterocyclic) Amino-Pyrimidines | DJUNG JANE F | 2007-12-20 | — | — | US | claimed |
| US-7105167-B2 | Methods for treating clinical manifestations of GH/GF axis dysregulation by administration of an IGF-I variant | GENENTECH, INC. (US) | 2006-09-12 | — | — | US | claimed |
| EP-1599477-A1 | SULFONAMIDE SUBSTITUTED XANTHINE DERIVATIVES FOR USE AS PEPCK INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2005-11-30 | — | — | EP | claimed |
| WO-2004074288-A1 | SULFONAMIDE SUBSTITUTED XANTHINE DERIVATIVES FOR USE AS PEPCK INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2004-09-02 | — | — | WO | claimed |
| CN-1034719-A | A kind of method of producing sulfapyrimidine | KUNSHAN PHARMACEUTICAL FACTORY (CN) | 1989-08-16 | — | — | CN | claimed |
| WO-2026107076-A1 | CDK2 INHIBITOR COMPOUNDS | ALEKSIA THERAPEUTICS, INC. (US) | 2026-05-21 | — | — | WO | disclosed |
| EP-4713096-A1 | CDK INHIBITOR COMPOUNDS | Aleksia Therapeutics, Inc. (US) | 2026-03-25 | — | — | EP | disclosed |
| CN-120172926-A | Preparation method and application of active substance with disease resistance and plant growth regulation functions | 贵州工业职业技术学院 | 2025-06-20 | — | — | CN | disclosed |
| WO-2024238574-A1 | CDK INHIBITOR COMPOUNDS | ALEKSIA THERAPEUTICS, INC. (US) | 2024-11-21 | — | — | WO | disclosed |
| US-12016312-B2 | Animal models, screening methods, and treatment methods for intraocular diseases or disorders | Smilebiotek Zhuhai Limited (CN) | 2024-06-25 | — | — | US | disclosed |
| US-4730051-A | 4-(substituted-oxy)-3-pyridinecarboxamides useful as plant growth inhibitory agents | DAICEL CHEMICAL INDUSTRIES LTD. (JP) | 1988-03-08 | — | — | US | disclosed |
| EP-0255100-A2 | Use of trimetrexate and its salts for the preparation of pharmaceutical compositions for treating infections of the mycobacterium-avium-intracellulare complex | WARNER-LAMBERT COMPANY (US) | 1988-02-03 | — | — | EP | disclosed |
| US-3950524-A | Hypoglycemic benzenesulfonamido pyrimidines | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-04-13 | — | — | US | disclosed |
| US-3950524-A | Hypoglycemic benzenesulfonamido pyrimidines | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-04-13 | — | — | US | disclosed |
| US-3941786-A | Process for the production of 4-hydroxy-6-hydroxymethylpyrimidine | LONZA LTD. (CH) | 1976-03-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070293494-A1 | 2-Anilino-4-(Heterocyclic) Amino-Pyrimidines | PRKCA, PRKCG, PRKCH | TSHR 3737/4885AURKA 289/4885DHFR 1013/4885 |
| US-20090227586-A1 | 2-ANILINO-4-(HETEROCYCLIC)AMINO-PYRIMIDINES | PRKCA, PRKCG, PRKCH | TSHR 3737/4885AURKA 289/4885DHFR 1013/4885 |
| US-12016312-B2 | Animal models, screening methods, and treatment methods for intraocular diseases or disorders | MB, MYOC, PDE6A | TSHR 2326/4885AURKA 3118/4885DHFR 2503/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.