Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | S100A4 | P26447 | 2/20 | 0.50 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MITF | O75030 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | PTPRC | P08575 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13046531 | 0.83 | S100A4 (0.47) | POLBS100A4KCNJ1KCNH2MAPT | |
| SCHEMBL7248426 | 0.79 | MAPT (0.50) | POLBS100A4MAPTRECQLKMT2A | |
| SCHEMBL27539899 | 0.79 | POLB (0.48) | POLBS100A4KCNJ1KCNH2MAPT | |
| SCHEMBL7248428 | 0.78 | S100A4 (0.46) | POLBS100A4MAPTRECQLKMT2A | |
| SCHEMBL6554331 | 0.78 | MAPT (0.40) | POLBS100A4KCNJ1KCNH2MAPT | |
| SCHEMBL16701465 | 0.76 | MAPT (0.50) | POLBS100A4MAPTRECQLKMT2A | |
| SCHEMBL2049186 | 0.75 | PGR (0.41) | POLBKCNJ1KCNH2MAPTKMT2A | |
| SCHEMBL2041366 | 0.75 | POLB (0.39) | POLBS100A4MAPTRECQLKMT2A | |
| SCHEMBL29947934 | 0.75 | PGR (0.41) | POLBKCNJ1KCNH2MAPTKMT2A | |
| SCHEMBL166701 | 0.74 | MAPT (0.56) | S100A4MAPTRECQLKMT2AMCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114076801-B | Detection method of related substances in lenalidomide | 上海博志研新药物研究有限公司 | 2024-04-02 | — | — | CN | claimed |
| CN-114076801-A | Method for detecting related substances in lenalidomide | 上海博志研新药物技术有限公司 | 2022-02-22 | — | — | CN | claimed |
| CN-1319944-C | Prepn process of N-methyl-4-(dimethyl phenoxy) phthalimide | SHANGHAI CITY INST OF SYNTHETI (CN) | 2007-06-06 | — | — | CN | claimed |
| CN-1706830-A | Prepn process of N-methyl-4-(dimethyl phenoxy) phthalimide | SHANGHAI CITY INST OF SYNTHETI (CN) | 2005-12-14 | — | — | CN | claimed |
| CN-114076801-B | Detection method of related substances in lenalidomide | 上海博志研新药物研究有限公司 | 2024-04-02 | — | — | CN | disclosed |
| WO-2022238500-A1 | RADIOSYNTHESIS OF [18F] TALAZOPARIB | EBERHARD KARLS UNIVERSITAET TUEBINGEN MEDIZINISCHE FAKULTAET (DE) | 2022-11-17 | — | — | WO | disclosed |
| EP-4088745-A1 | COMPOUND FOR THE DIAGNOSIS OF CANCER | Eberhard Karls Universität Tübingen Medizinische Fakultät (DE) | 2022-11-16 | — | — | EP | disclosed |
| EP-4089093-A1 | RADIOSYNTHESIS OF [18F] TALAZOPARIB | Eberhard Karls Universität Tübingen Medizinische Fakultät (DE) | 2022-11-16 | — | — | EP | disclosed |
| US-11364241-B2 | Dihydropyridophthalazinone inhibitors of poly(ADP-ribose)polymerase (PARP) | MEDIVATION TECHNOLOGIES LLC (US) | 2022-06-21 | — | — | US | disclosed |
| CN-114076801-A | Method for detecting related substances in lenalidomide | 上海博志研新药物技术有限公司 | 2022-02-22 | — | — | CN | disclosed |
| US-20210069191-A1 | DIHYDROPYRIDOPHTHALAZINONE INHIBITORS OF POLY(ADP-RIBOSE)POLYMERASE (PARP) | MEDIVATION TECHNOLOGIES LLC | 2021-03-11 | — | — | US | disclosed |
| US-10780088-B2 | Dihydropyridophthalazinone inhibitors of poly(ADP-ribose)polymerase (PARP) | MEDIVATION TECHNOLOGIES LLC (US) | 2020-09-22 | — | — | US | disclosed |
| US-20050171109-A1 | Tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2005-08-04 | — | — | US | disclosed |
| US-20050131226-A1 | Rearranged pentanols, a process for their production and their use as anti-inflammatory agents | SCHERING AG (DE) | 2005-06-16 | — | — | US | disclosed |
| WO-2005035518-A1 | REARRANGED PENTANOLS, A METHOD FOR THE PRODUCTION THEREOF, AND THEIR USE AS ANTIPHLOGISTICS | SCHERING AKTIENGESELLSCHAFT (DE) | 2005-04-21 | — | — | WO | disclosed |
| WO-2005034939-A1 | 1-AMINO-2-OXY-SUBSTITUTED TETRAHYDRONAPHTALENE DERIVATIVES, METHODS FOR THE PRODUCTION THEREOF, AND THEIR USE AS ANTIPHLOGISTICS | SCHERING AKTIENGESELLSCHAFT (DE) | 2005-04-21 | — | — | WO | disclosed |
| US-20030073850-A1 | 4-Imidazole derivatives of benzyl and restricted benzyl sulfonamides, sulfamides, ureas, carbamates, and amides and their use | ABBOTT LABORATORIES | 2003-04-17 | — | — | US | disclosed |
| US-4687508-A | Herbicidal benzenesulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-08-18 | — | — | US | disclosed |
| US-4578108-A | Herbicidal benzenesulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1986-03-25 | — | — | US | disclosed |
| US-4521241-A | PLANT GROWTH REGULATORS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-06-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10780088-B2 | Dihydropyridophthalazinone inhibitors of poly(ADP-ribose)polymerase (PARP) | PARP1, PARP2, PARP11 | POLB 19/4885S100A4 4760/4885KCNJ1 3516/4885 |
| US-20030073850-A1 | 4-Imidazole derivatives of benzyl and restricted benzyl sulfonamides, sulfamides, ureas, carbamates, and amides and their use | ADRA1D, ADRB1, ADRA1A | POLB 4410/4885S100A4 1602/4885KCNJ1 555/4885 |
| US-11364241-B2 | Dihydropyridophthalazinone inhibitors of poly(ADP-ribose)polymerase (PARP) | PARP1, PARP2, PARP11 | POLB 19/4885S100A4 4760/4885KCNJ1 3516/4885 |
| US-20050171109-A1 | Tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents | TNF, DHPS, PTGES | POLB 2124/4885S100A4 988/4885KCNJ1 3846/4885 |
| US-20050131226-A1 | Rearranged pentanols, a process for their production and their use as anti-inflammatory agents | TNF, PTGES, PTGES2 | POLB 1150/4885S100A4 1185/4885KCNJ1 4638/4885 |
| US-20210069191-A1 | DIHYDROPYRIDOPHTHALAZINONE INHIBITORS OF POLY(ADP-RIBOSE)POLYMERASE (PARP) | PARP1, PARP2, PARP11 | POLB 19/4885S100A4 4760/4885KCNJ1 3516/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.